EC 1.2.1.79: succinate-semialdehyde dehydrogenase (NADP+)
OxidoreductasesOpen in Browse
CatLog read 49 records for EC 1.2.1.79 from 4 papers, for 4 organisms. Names in these papers: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1), succinic semialdehyde dehydrogenase (cce4228 protein), ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase, succinic semialdehyde dehydrogenase (cce4228) and 2 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 32 records for EC 1.2.1.79 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.2.1.79 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Kinetic and structural insights into enzymatic mechanism of succinic semialdehyde dehydrogenase from Cyanothece sp. ATCC51142 | Cyanothece sp. ATCC51142 | 20 |
| Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants | Arabidopsis thaliana | 16 |
| The ALDH21 gene found in lower plants and some vascular plants codes for a NADP+ -dependent succinic semialdehyde dehydrogenase | Physcomitrella patens | 11 |
| Kinetic and structural characterization for cofactor preference of succinic semialdehyde dehydrogenase from Streptococcus pyogenes | Streptococcus pyogenes | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase | Physcomitrella patens | glutaric semialdehyde | 0.27 | 0.551 | 0.5 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase, glutaric semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase | Physcomitrella patens | NAD+ | 3.3 | 5.37 | 0.62 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase, NAD+ |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase | Physcomitrella patens | NADP+ | 15.2 | 0.024 | 630 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase, NADP+ |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase | Physcomitrella patens | succinic semialdehyde | 15.8 | 0.181 | 87 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase, succinic semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant N175A | Physcomitrella patens | succinic semialdehyde | 12.5 | 1.49 | 8.4 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant N175A, succinic semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant R121A | Physcomitrella patens | succinic semialdehyde | 0.02 | 0.268 | 0.088 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant R121A, succinic semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant R228A | Physcomitrella patens | NAD+ | 1.2 | 8.44 | 0.14 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant R228A, NAD+ |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant R228A | Physcomitrella patens | NADP+ | 6.4 | 0.375 | 17 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant R228A, NADP+ |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant R228A | Physcomitrella patens | succinic semialdehyde | 5.7 | 0.127 | 45 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant R228A, succinic semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant R457A | Physcomitrella patens | succinic semialdehyde | 0.02 | 0.135 | 0.18 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant R457A, succinic semialdehyde |
| ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenasevariant Y296A | Physcomitrella patens | succinic semialdehyde | 7.1 | 0.127 | 56 | pH 8.2, 30 °C | PMID 28749584 | Open record: ALDH21 (PpALDH21), NADP+-dependent succinic semialdehyde dehydrogenase variant Y296A, succinic semialdehyde |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) | Arabidopsis thaliana | 3-hydroxypyruvate (lithium beta-hydroxypyruvate) | — | 6.1 | 0.232 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1), 3-hydroxypyruvate (lithium beta-hydroxypyruvate) |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) | Arabidopsis thaliana | glyoxylate | 54.6 | 0.018 | 3407 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1), glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) | Arabidopsis thaliana | NADPH | 84.1 | 0.00344 | 2.43 × 10⁴ | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1), NADPH |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant D239A | Arabidopsis thaliana | glyoxylate | 22 | 3 | 7.45 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant D239A, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant D239A | Arabidopsis thaliana | NADPH | 25.4 | 0.00273 | 1.04 × 10⁴ | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant D239A, NADPH |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant F231A | Arabidopsis thaliana | glyoxylate | 11 | 12.4 | 0.87 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant F231A, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant F231A | Arabidopsis thaliana | NADPH | 9.56 | 0.00204 | 4.34 × 10³ | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant F231A, NADPH |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant K170E | Arabidopsis thaliana | glyoxylate | 0.0052 | 0.033 | 0.19 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant K170E, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant K170R | Arabidopsis thaliana | glyoxylate | 0.051 | 0.061 | 0.86 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant K170R, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant N174A | Arabidopsis thaliana | glyoxylate | 6.06 | 0.088 | 72.8 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant N174A, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant N174A | Arabidopsis thaliana | NADPH | 9.09 | 9.02 × 10⁻⁴ | 1.09 × 10⁴ | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant N174A, NADPH |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant S121A | Arabidopsis thaliana | glyoxylate | 86.4 | 0.181 | 480 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant S121A, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant S121A | Arabidopsis thaliana | NADPH | 93.7 | 0.0018 | 5.17 × 10⁴ | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant S121A, NADPH |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant T95A | Arabidopsis thaliana | glyoxylate | 67.8 | 4.6 | 14.6 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant T95A, glyoxylate |
| AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1)variant T95A | Arabidopsis thaliana | NADPH | 51.1 | 0.0648 | 779 | pH 7.8 | PMID 24076009 | Open record: AtGLYR1 (cytosolic NADPH-dependent glyoxylate reductase 1) variant T95A, NADPH |
| AtGLYR2 (plastidial NADPH-dependent glyoxylate reductase 2) | Arabidopsis thaliana | glyoxylate | — | 0.016 | — | pH 7.8 | PMID 24076009 | Open record: AtGLYR2 (plastidial NADPH-dependent glyoxylate reductase 2), glyoxylate |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant E360A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.139 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant E360A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant E360A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 2.8 | 0.01 | 280 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant E360A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant R139A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.023 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant R139A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant R139A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 0.54 | 0.112 | 4.8 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant R139A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant S207A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.008 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant S207A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant S207A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 0.17 | 0.006 | 28.3 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant S207A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant S420A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.025 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant S420A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant S420A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 9.3 | 0.07 | 133 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant S420A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant W130A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.024 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant W130A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant W130A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 2.4 | 0.02 | 120 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant W130A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant W135A | Cyanothece sp. ATCC51142 | NADP+ | — | 0.018 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant W135A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228 protein)variant W135A | Cyanothece sp. ATCC51142 | succinic semialdehyde | 2 | 0.0195 | 102 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228 protein) variant W135A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228)variant K154A | Cyanothece sp. ATCC51142 | NAD+ | — | 1.5 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant K154A, NAD+ |
| succinic semialdehyde dehydrogenase (cce4228)variant K154A | Cyanothece sp. ATCC51142 | NADP+ | — | 6.1 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant K154A, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228)variant K154A | Cyanothece sp. ATCC51142 | succinic semialdehydeNADP+ fixed at 8 mM; cosubstrate NADP+ | 0.1 | 0.02 | 5 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant K154A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228)variant K154A | Cyanothece sp. ATCC51142 | succinic semialdehydeNAD+ fixed at 5 mM; cosubstrate NAD+ | 0.13 | 0.02 | 6.5 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant K154A, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228)variant S157E | Cyanothece sp. ATCC51142 | NAD+ | — | 0.51 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant S157E, NAD+ |
| succinic semialdehyde dehydrogenase (cce4228)variant S157E | Cyanothece sp. ATCC51142 | NADP+ | — | 1.1 | — | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant S157E, NADP+ |
| succinic semialdehyde dehydrogenase (cce4228)variant S157E | Cyanothece sp. ATCC51142 | succinic semialdehydeNADP+ fixed at 10 mM; cosubstrate NADP+ | 1.5 | 0.0028 | 535 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant S157E, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (cce4228)variant S157E | Cyanothece sp. ATCC51142 | succinic semialdehydeNAD+ fixed at 6 mM; cosubstrate NAD+ | 0.58 | 0.003 | 193 | pH 9, 25 °C | PMID 32966327 | Open record: succinic semialdehyde dehydrogenase (cce4228) variant S157E, succinic semialdehyde |
| succinic semialdehyde dehydrogenase (SpSSADH) | Streptococcus pyogenes | NAD+ | 1.94 | 0.23 | 9.7 | pH 7, 30 °C | PMID 25256219 | Open record: succinic semialdehyde dehydrogenase (SpSSADH), NAD+ |
| succinic semialdehyde dehydrogenase (SpSSADH) | Streptococcus pyogenes | NADP+ | 7.2 | 0.1 | 72 | pH 7, 30 °C | PMID 25256219 | Open record: succinic semialdehyde dehydrogenase (SpSSADH), NADP+ |