CatLogenzyme kinetics catalog

EC 1.2.4.2: oxoglutarate dehydrogenase (succinyl-transferring)

OxidoreductasesOpen in Browse

CatLog read 11 records for EC 1.2.4.2 from 3 papers, for 3 organisms. Names in these papers: 2-oxoglutarate dehydrogenase (E1o), 2-oxoglutarate dehydrogenase complex (ODH), alpha-ketoglutarate decarboxylase (Kgd; Rv1248c protein, annotated SucA), OdhA (E1 domain, 2-oxoglutarate dehydrogenase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 47 records for EC 1.2.4.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.2.4.2 in Browse.

Papers

PaperOrganismsRecords
doi:10.1002/aic.16769Escherichia coli6
The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceFCorynebacterium glutamicum4
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylaseMycobacterium tuberculosis1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
2-oxoglutarate dehydrogenase (E1o)Escherichia coli2-oxo-5-hexenoic acid0.05958.010.0074doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase (E1o)Escherichia coli2-oxoglutaric acid2.70.006456.6doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase (E1o)Escherichia coli2-oxovaleric acid0.1528.180.0165doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase (E1o)variant H298DEscherichia coli2-oxo-5-hexenoic acid0.14811.10.0134doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase (E1o)variant H298DEscherichia coli2-oxoglutaric acid0.731.870.39doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase (E1o)variant H298DEscherichia coli2-oxovaleric acid0.486.620.0725doi:10.1002/aic.16769Open
2-oxoglutarate dehydrogenase complex (ODH)Corynebacterium glutamicum2-oxoglutarate—0.13—pH 7.7PMID 20675489Open
2-oxoglutarate dehydrogenase complex (ODH)variant AceF K162Q/K278QCorynebacterium glutamicum2-oxoglutarate—0.32—pH 7.7PMID 20675489Open
2-oxoglutarate dehydrogenase complex (ODH)variant AceF K43Q/K162QCorynebacterium glutamicum2-oxoglutarate—0.17—pH 7.7PMID 20675489Open
alpha-ketoglutarate decarboxylase (Kgd; Rv1248c protein, annotated SucA)Mycobacterium tuberculosis2-oxoglutarate—0.48—PMID 16027371Open
OdhA (E1 domain, 2-oxoglutarate dehydrogenase)Corynebacterium glutamicum2-oxoglutarate—0.014—pH 7.5PMID 20675489Open