CatLogenzyme kinetics catalog

EC 1.21.1.1: iodotyrosine deiodinase

OxidoreductasesOpen in Browse

CatLog read 23 records for EC 1.21.1.1 from 4 papers, for 7 organisms. Names in these papers: iodotyrosine deiodinase (HsIYD), iodotyrosine deiodinase (TnIYD), iodotyrosine deiodinase (hhIYD), iodotyrosine deiodinase (IYD) and 4 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 17 records for EC 1.21.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.21.1.1 in Browse.

Papers

PaperOrganismsRecords
Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine DeiodinaseHaliscomenobacter hydrossis, Homo sapiens6
The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitanaThermotoga neapolitana6
doi:10.1021/acscatal.8b03587Homo sapiens6
Iodotyrosine deiodinase: a unique flavoprotein present in organisms of diverse phylaHaliscomenobacter hydrossis, daphnia and 3 more5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
iodotyrosine deiodinase (dpIYD)daphniadiiodotyrosine0.2930.00742PMID 24153409Open
iodotyrosine deiodinase (drIYD)zebrafishdiiodotyrosine0.0680.0088.5PMID 24153409Open
iodotyrosine deiodinase (hhIYD)Haliscomenobacter hydrossis2-iodophenol0.00294.17 × 10⁻⁴pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (hhIYD)Haliscomenobacter hydrossis3-iodo-L-tyrosine0.270.0012230pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (hhIYD)Haliscomenobacter hydrossis4-amino-2-iodophenol——0.0041pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (hhIYD)Haliscomenobacter hydrossis4-hydroxy-3-iodobenzoic acid0.00317.14.4 × 10⁻⁴pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (hhIYD)Haliscomenobacter hydrossisdiiodotyrosine0.090.006613PMID 24153409Open
iodotyrosine deiodinase (hmIYD)hydradiiodotyrosine0.230.00458PMID 24153409Open
iodotyrosine deiodinase (HsIYD)variant E157D/E158Y/M162A (TM01)Homo sapiens2-iodophenol0.0162.90.0055pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (HsIYD)variant E157D/E158Y/M162A (TM01)Homo sapiensmonoiodotyrosine0.530.134.2pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (HsIYD)variant E158Y/M162A (DM01)Homo sapiens2-iodophenol0.017250.0035pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (HsIYD)variant E158Y/M162A (DM01)Homo sapiensmonoiodotyrosine0.0730.001452pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (HsIYD)variant UD08Homo sapiens2-iodophenol0.01533.40.0045pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (HsIYD)variant UD08Homo sapiensmonoiodotyrosine0.095150.0065pH 7.4, 25 °Cdoi:10.1021/acscatal.8b03587Open
iodotyrosine deiodinase (IYD)Homo sapiens2-iodophenol0.0044.10.001pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (IYD)Homo sapiens3-iodo-L-tyrosine0.1020.007314pH 7.4, 25 °CPMID 28157283Open
iodotyrosine deiodinase (nvIYD)sea anemonediiodotyrosine0.530.1055PMID 24153409Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitana2-iodophenol0.0144.20.0033pH 7.4, 25 °CPMID 34748729Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitana2-iodophenol0.1086.60.0165pH 7.4, 60 °CPMID 34748729Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitanaBr-Tyr0.0851.4 × 10⁻⁴600pH 7.4, 60 °CPMID 34748729Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitanaCl-Tyr0.0480.00510pH 7.4, 60 °CPMID 34748729Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitanaI-Tyr0.0272.2 × 10⁻⁴120pH 7.4, 25 °CPMID 34748729Open
iodotyrosine deiodinase (TnIYD)Thermotoga neapolitanaI-Tyr0.450.0035170pH 7.4, 60 °CPMID 34748729Open