CatLogenzyme kinetics catalog

EC 1.3.3.4: protoporphyrinogen oxidase

OxidoreductasesOpen in Browse

CatLog read 35 records for EC 1.3.3.4 from 4 papers, for 4 organisms. Names in these papers: PPO2 (mitochondrial protoporphyrinogen IX oxidase), protoporphyrinogen oxidase (hPPO), protoporphyrinogen oxidase (MxPPOX), protoporphyrinogen oxidase (PPO).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 63 records for EC 1.3.3.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.3.3.4 in Browse.

Papers

PaperOrganismsRecords
Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding siteNicotiana tabacum13
Computational and experimental insights into the mechanism of substrate recognition and feedback inhibition of protoporphyrinogen oxidaseHomo sapiens11
Characterisation of the flavin adenine dinucleotide binding region of Myxococcus xanthus protoporphyrinogen oxidaseMyxococcus xanthus8
Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilisBacillus subtilis3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
PPO2 (mitochondrial protoporphyrinogen IX oxidase)Nicotiana tabacumprotoporphyrinogen IX60.001175.1 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant F392ENicotiana tabacumprotoporphyrinogen IX110.01121 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant L356NNicotiana tabacumprotoporphyrinogen IX380.0113.4 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant L356VNicotiana tabacumprotoporphyrinogen IX3000.00734.11 × 10⁴pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant L372NNicotiana tabacumprotoporphyrinogen IX70.0164400pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant L372VNicotiana tabacumprotoporphyrinogen IX5970.1035.8 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant N67RNicotiana tabacumprotoporphyrinogen IX970.0971 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant N67R/S374DNicotiana tabacumprotoporphyrinogen IX1110.00147.94 × 10⁴pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant N67W/S374DNicotiana tabacumprotoporphyrinogen IX120.021570pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant R98ANicotiana tabacumprotoporphyrinogen IX3650.00834.4 × 10⁴pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant R98ENicotiana tabacumprotoporphyrinogen IX340.01252.7 × 10³pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant R98KNicotiana tabacumprotoporphyrinogen IX370.00261.44 × 10⁴pH 6, 20 °CPMID 17134376Open
PPO2 (mitochondrial protoporphyrinogen IX oxidase)variant S374DNicotiana tabacumprotoporphyrinogen IX2080.01091.85 × 10⁴pH 6, 20 °CPMID 17134376Open
protoporphyrinogen oxidase (hPPO)Homo sapiensprotoporphyrinogen IX0.04950.0020823.8pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant F331AHomo sapiensprotoporphyrinogen IX0.07270.006611pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant F331THomo sapiensprotoporphyrinogen IX0.15130.0030250.2pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant G169AHomo sapiensprotoporphyrinogen IX0.00620.002162.8pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant L166NHomo sapiensprotoporphyrinogen IX0.03030.005135.8pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant L334VHomo sapiensprotoporphyrinogen IX0.85320.00708120.5pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant M368KHomo sapiensprotoporphyrinogen IX0.23620.0056342pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant M368QHomo sapiensprotoporphyrinogen IX0.15480.0138911.2pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant R168SHomo sapiensprotoporphyrinogen IX0.05530.011334.8pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant R97GHomo sapiensprotoporphyrinogen IX1.2730.0196464.8pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (hPPO)variant V170THomo sapiensprotoporphyrinogen IX0.12830.0029743.2pH 7.4PMID 23935953Open
protoporphyrinogen oxidase (MxPPOX)Myxococcus xanthusprotoporphyrinogen IX0.723.8 × 10⁻⁴1.88 × 10³pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant E39DMyxococcus xanthusprotoporphyrinogen IX1.525.9 × 10⁻⁴2.58 × 10³pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant N441IMyxococcus xanthusprotoporphyrinogen IX0.085.1 × 10⁻⁴160pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant N441QMyxococcus xanthusprotoporphyrinogen IX0.327.5 × 10⁻⁴430pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant S20AMyxococcus xanthusprotoporphyrinogen IX0.419.2 × 10⁻⁴450pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant S20TMyxococcus xanthusprotoporphyrinogen IX0.780.00117670pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant W408LMyxococcus xanthusprotoporphyrinogen IX0.145.1 × 10⁻⁴280pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (MxPPOX)variant W408YMyxococcus xanthusprotoporphyrinogen IX0.230.00149150pH 8.1, 37 °CPMID 29124218Open
protoporphyrinogen oxidase (PPO)Bacillus subtiliscoproporphyrinogen-III8.3 × 10⁻⁴0.005290.16 calc.pH 8.7PMID 9784236Open
protoporphyrinogen oxidase (PPO)Bacillus subtilismesoporphyrinogen-IX0.04480.004929.11 calc.pH 8.7PMID 9784236Open
protoporphyrinogen oxidase (PPO)Bacillus subtilisprotoporphyrinogen-IX0.00320.0013.2 calc.pH 8.7PMID 9784236Open