EC 1.3.99.3: acyl-CoA dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 39 records for EC 1.3.99.3 from 3 papers, for 2 organisms. Names in these papers: medium-chain acyl-CoA dehydrogenase (MCADH), medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, medium-chain acyl-CoA dehydrogenase.
EC 1.3.99.3 is no longer current; BRENDA: “transferred to EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase, EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase”.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Medium-long-chain chimeric human Acyl-CoA dehydrogenase: medium-chain enzyme with the active center base arrangement of long-chain Acyl-CoA dehydrogenase | Homo sapiens | 18 |
| Intrinsic isomerase activity of medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | 13 |
| Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the… | Rattus norvegicus | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Butyryl-CoA | 3.8 | 0.135 | 28 | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Butyryl-CoA |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Decanoyl-CoA | 25.2 | 0.0054 | 4.67 × 10³ | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Decanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | electron-transfer flavoprotein | 16.8 | 0.0045 | 3.73 × 10³ | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, electron-transfer flavoprotein |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Hexanoyl-CoA | 31.2 | 0.0094 | 3.32 × 10³ | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Hexanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Lauroyl-CoA | 11.7 | 0.0057 | 2.05 × 10³ | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Lauroyl-CoA |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Octanoyl-CoA | 27.2 | 0.004 | 6.8 × 10³ | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | phenazine methosulfate | 27 | 1.2 | 20 | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, phenazine methosulfate |
| medium-chain acyl-CoA dehydrogenase | Rattus norvegicus | Valeryl-CoA | 25.4 | 0.0396 | 640 | pH 8, 32 °C | PMID 3968063 | Open record: medium-chain acyl-CoA dehydrogenase, Valeryl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | cis-3-decenoyl-CoA | 0.01 | 0.062 | 0.16 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, cis-3-decenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | cis-3-hexenoyl-CoA | 0.11 | 0.02 | 5.5 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, cis-3-hexenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | cis-3-octenoyl-CoA | 0.016 | 0.03 | 0.53 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, cis-3-octenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | octanoyl-CoA | 3.2 | 0.0023 | 1.4 × 10³ | pH 7.4 | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | trans-3-decenoyl-CoA | 0.0044 | 0.053 | 0.083 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, trans-3-decenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | trans-3-hexenoyl-CoA | 0.032 | 0.015 | 2.1 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, trans-3-hexenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial | Rattus norvegicus | trans-3-octenoyl-CoA | 0.0086 | 0.022 | 0.39 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial, trans-3-octenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | cis-3-decenoyl-CoA | 0.09 | 0.023 | 3.9 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, cis-3-decenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | cis-3-hexenoyl-CoA | 0.47 | 0.014 | 34 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, cis-3-hexenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | cis-3-octenoyl-CoA | 0.1 | 0.018 | 5.6 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, cis-3-octenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | octanoyl-CoA | 0.79 | 0.0056 | 140 | pH 7.4 | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | trans-3-hexenoyl-CoA | 0.013 | 0.023 | 0.57 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, trans-3-hexenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrialvariant E376D | Rattus norvegicus | trans-3-octenoyl-CoA | 0.0079 | 0.031 | 0.25 | pH 7.5, 25 °C | PMID 15850406 | Open record: medium-chain acyl-CoA dehydrogenase (MCAD), mitochondrial variant E376D, trans-3-octenoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | butanoyl-CoA | 8.3 | 0.175 | 50 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), butanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | decanoyl-CoA | 9.7 | 0.0025 | 3.87 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), decanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | dodecanoyl-CoA | 9.2 | 0.0025 | 3.7 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), dodecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | hexadecanoyl-CoA | 2.3 | 0.0016 | 1.47 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), hexadecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | hexanoyl-CoA | 16.8 | 0.015 | 1.12 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), hexanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | octanoyl-CoA | 16.3 | 0.0034 | 4.8 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH) | Homo sapiens | tetradecanoyl-CoA | 4.7 | 0.0023 | 2.03 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH), tetradecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E | Homo sapiens | butanoyl-CoA | 8.3 | 0.07 | 120 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E, butanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E | Homo sapiens | decanoyl-CoA | 11.3 | 0.01 | 1.13 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E, decanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E | Homo sapiens | hexanoyl-CoA | 2.8 | 0.0014 | 2.02 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E, hexanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E | Homo sapiens | octanoyl-CoA | 13.2 | 0.008 | 1.65 × 10³ | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E, octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376G | Homo sapiens | decanoyl-CoA | 0.33 | 0.0042 | 83 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376G, decanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376G | Homo sapiens | dodecanoyl-CoA | 3.3 | 0.0066 | 500 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376G, dodecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376G | Homo sapiens | hexadecanoyl-CoA | 0.62 | 0.0013 | 470 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376G, hexadecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376G | Homo sapiens | octanoyl-CoA | 0.17 | 0.001 | 170 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376G, octanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376G | Homo sapiens | tetradecanoyl-CoA | 2.7 | 0.0055 | 480 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376G, tetradecanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376T | Homo sapiens | decanoyl-CoA | 0.23 | 0.05 | 5 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376T, decanoyl-CoA |
| medium-chain acyl-CoA dehydrogenase (MCADH)variant T255E/E376T | Homo sapiens | dodecanoyl-CoA | 0.1 | 0.05 | 1.7 | pH 7.6, 25 °C | PMID 8823175 | Open record: medium-chain acyl-CoA dehydrogenase (MCADH) variant T255E/E376T, dodecanoyl-CoA |