EC 1.5.3.13: N1-acetylpolyamine oxidase
OxidoreductasesOpen in Browse
CatLog read 25 records for EC 1.5.3.13 from 3 papers, for 2 organisms. Names in these papers: N1-acetylspermine oxidase (APAO), polyamine oxidase (PAO), acetylpolyamine oxidase (APAO).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 5 records for EC 1.5.3.13 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.5.3.13 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The Structure of Murine N1-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism | Mus musculus | 10 |
| Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines | Homo sapiens | 8 |
| Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators | Homo sapiens | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-acetylspermidine | 2.7 | 0.0082 | 330 | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-acetylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-benzoyl-(R)-1-methylspermidine | 4.6 | 0.0012 | 3.8 × 10³ | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-benzoyl-(R)-1-methylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-benzoyl-(S)-1-methylspermidine | 0.03 | 2 × 10⁻⁴ | 150 | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-benzoyl-(S)-1-methylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-benzyl-(R)-1-methylspermidine | 0.14 | 0.002 | 71 | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-benzyl-(R)-1-methylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-benzyl-(S)-1-methylspermidine | 0.03 | 0.0016 | 18 | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-benzyl-(S)-1-methylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-isonicotinoyl-(R)-1-methylspermidine | 5.2 | 0.0036 | 1.4 × 10³ | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-isonicotinoyl-(R)-1-methylspermidine |
| acetylpolyamine oxidase (APAO) | Homo sapiens | N1-isonicotinoyl-(S)-1-methylspermidine | 0.01 | 8 × 10⁻⁴ | 18 | pH 9.5 | PMID 30006473 | Open record: acetylpolyamine oxidase (APAO), N1-isonicotinoyl-(S)-1-methylspermidine |
| N1-acetylspermine oxidase (APAO) | Mus musculus | N1-acetylspermine | 27 | 0.003 | 9.6 × 10³ | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO), N1-acetylspermine |
| N1-acetylspermine oxidase (APAO) | Mus musculus | spermine | 8 | 8 | 1 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO), spermine |
| N1-acetylspermine oxidase (APAO)variant N313A | Mus musculus | N1-acetylspermine | 25 | 0.1 | 277 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313A, N1-acetylspermine |
| N1-acetylspermine oxidase (APAO)variant N313A | Mus musculus | spermine | 8.8 | 9 | 1 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313A, spermine |
| N1-acetylspermine oxidase (APAO)variant N313D | Mus musculus | N1-acetylspermine | 27 | 0.2 | 137 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313D, N1-acetylspermine |
| N1-acetylspermine oxidase (APAO)variant N313D | Mus musculus | spermine | 5.2 | 6 | 0.9 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313D, spermine |
| N1-acetylspermine oxidase (APAO)variant N313L | Mus musculus | N1-acetylspermine | 25 | 0.2 | 144 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313L, N1-acetylspermine |
| N1-acetylspermine oxidase (APAO)variant N313L | Mus musculus | spermine | 7.5 | 7 | 1.1 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313L, spermine |
| N1-acetylspermine oxidase (APAO)variant N313T | Mus musculus | N1-acetylspermine | 22 | 0.12 | 175 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313T, N1-acetylspermine |
| N1-acetylspermine oxidase (APAO)variant N313T | Mus musculus | spermine | 8.7 | 11 | 0.8 | pH 9, 30 °C | PMID 28029774 | Open record: N1-acetylspermine oxidase (APAO) variant N313T, spermine |
| polyamine oxidase (PAO) | Homo sapiens | bis-α-methylspermine (1,12-dimethylspermine) | — | 0.047 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), bis-α-methylspermine (1,12-dimethylspermine) |
| polyamine oxidase (PAO) | Homo sapiens | spermidine | — | 0.015 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), spermidine |
| polyamine oxidase (PAO) | Homo sapiens | spermine | — | 0.047 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), spermine |
| polyamine oxidase (PAO) | Homo sapiens | sperminewith 5 mM benzaldehyde | — | 0.0093 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), spermine |
| polyamine oxidase (PAO) | Homo sapiens | α-methylspermine | — | 0.019 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), α-methylspermine |
| polyamine oxidase (PAO) | Homo sapiens | α-methylsperminewith 5 mM benzaldehyde | — | 0.012 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), α-methylspermine |
| polyamine oxidase (PAO) | Homo sapiens | α-methylspermine | — | 0.017 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), α-methylspermine |
| polyamine oxidase (PAO) | Homo sapiens | α-methylsperminewith 5 mM benzaldehyde | — | 0.011 | — | pH 9.5, 37 °C | PMID 15611107 | Open record: polyamine oxidase (PAO), α-methylspermine |