EC 1.6.5.9: NADH:quinone reductase (non-electrogenic)
OxidoreductasesOpen in Browse
CatLog read 66 records for EC 1.6.5.9 from 4 papers, for 4 organisms. Names in these papers: type II NADH:ubiquinone oxidoreductase (PfNDH2), Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase), NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), NADH:quinone oxidoreductase (NQO).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 32 records for EC 1.6.5.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.6.5.9 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Reactions of Plasmodium falciparum Type II NADH: Ubiquinone Oxidoreductase with Nonphysiological Quinoidal and Nitroaromatic Oxidants | Plasmodium falciparum | 33 |
| Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors | Saccharomyces cerevisiae | 23 |
| Purification of the 45 kDa, membrane bound NADH dehydrogenase of Escherichia coli (NDH-2) and analysis of its interaction with ubiquinone analogues | Escherichia coli | 6 |
| Mechanistic and Molecular Dynamics Studies Reveal that Increased Loop 3 Mobility Alters Substrate Capture in an NADH:Quinone Oxidoreductase | Pseudomonas aeruginosa | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| NADH:quinone oxidoreductase (NQO) | Pseudomonas aeruginosa | coenzyme Q0 | 11 | 0.035 | 320 | pH 6, 25 °C | PMID 41388968 | Open record: NADH:quinone oxidoreductase (NQO), coenzyme Q0 |
| NADH:quinone oxidoreductase (NQO) | Pseudomonas aeruginosa | NADH | — | 4 × 10⁻⁴ | 2.8 × 10⁴ | pH 6, 25 °C | PMID 41388968 | Open record: NADH:quinone oxidoreductase (NQO), NADH |
| NADH:quinone oxidoreductase (NQO)variant P78G | Pseudomonas aeruginosa | coenzyme Q0 | 5.4 | 0.01 | 560 | pH 6, 25 °C | PMID 41388968 | Open record: NADH:quinone oxidoreductase (NQO) variant P78G, coenzyme Q0 |
| NADH:quinone oxidoreductase (NQO)variant P78G | Pseudomonas aeruginosa | NADH | — | 0.13 | 43 | pH 6, 25 °C | PMID 41388968 | Open record: NADH:quinone oxidoreductase (NQO) variant P78G, NADH |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | decylubiquinone (decylbenzoquinone) | — | 0.0187 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), decylubiquinone (decylbenzoquinone) |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | dichlorophenolindophenol | — | 0.02 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), dichlorophenolindophenol |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | idebenone (hydroxidecyl benzoquinone) | — | 0.0018 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), idebenone (hydroxidecyl benzoquinone) |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | NADH | — | 0.034 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), NADH |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | ubiquinone-1 | — | 0.0059 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), ubiquinone-1 |
| NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase) | Escherichia coli | ubiquinone-2 | — | 0.0023 | — | pH 7.5, 30 °C | PMID 10664466 | Open record: NADH:ubiquinone reductase NDH-2 (type II NADH dehydrogenase), ubiquinone-2 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0227 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase), ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant A393G | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0325 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant A393G, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant H397A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.035 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant H397A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant I459A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0402 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant I459A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant I459N | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0303 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant I459N, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant I459W | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0756 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant I459W, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant L444D | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0376 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant L444D, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant L444N | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0239 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant L444N, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant L447N | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0179 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant L447N, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant L487A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0164 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant L487A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant M485A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0186 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant M485A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant M485E | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0635 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant M485E, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant P92A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0256 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant P92A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant Q394A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0245 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant Q394A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant Q394G | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0308 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant Q394G, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant R479A | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0115 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant R479A, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant R479H | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0235 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant R479H, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant R479I | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0277 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant R479I, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant R479K | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.00937 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant R479K, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant S484F | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0245 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant S484F, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant S484I | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.025 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant S484I, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant W63F | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0531 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant W63F, ubiquinone-1 |
| Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase)variant Y482F | Saccharomyces cerevisiae | ubiquinone-1 | — | 0.0233 | — | pH 6 | PMID 29402945 | Open record: Ndi1 (type II NADH dehydrogenase, NADH-ubiquinone oxidoreductase) variant Y482F, ubiquinone-1 |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,2-dinitrobenzene | 1.1 | — | 3.54 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,2-dinitrobenzene |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,3-dinitrobenzene | 0.6 | — | 3.37 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,3-dinitrobenzene |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,4-Benzoquinone | 14 | — | 330 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,4-Benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinone | — | — | 2.02 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,4-Dihydroxy-9,10-anthraquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,4-dinitrobenzene | 7.35 | — | 60.9 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,4-dinitrobenzene |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,4-Naphthoquinone | 17.5 | — | 545 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,4-Naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 1,8-Dihydroxy-9,10-anthraquinone | — | — | 4.41 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 1,8-Dihydroxy-9,10-anthraquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2,4,6-trinitrophenyl-N-methylnitramine | 7.4 | — | 150 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2,4,6-trinitrophenyl-N-methylnitramine |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2,4,6-Trinitrotoluene | 2.4 | — | 32 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2,4,6-Trinitrotoluene |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2,5-diaziridinyl-1,4-benzoquinone | 9 | — | 372 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2,5-diaziridinyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone | 1.6 | — | 57.2 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2,6-Dimethyl-1,4-benzoquinone | 10.8 | — | 285 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2,6-Dimethyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2-Hydroxy-1,4-naphthoquinone | 0.42 | — | 17.5 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2-Hydroxy-1,4-naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2-Methyl-1,4-benzoquinone | 8.5 | — | 210 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2-Methyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 2-methyl-1,4-naphthoquinone | 7.05 | — | 925 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 2-methyl-1,4-naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 4-nitroacetophenone | — | — | 0.27 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 4-nitroacetophenone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 4-nitrobenzaldehyde | 1.5 | — | 0.995 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 4-nitrobenzaldehyde |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 4-nitrobenzoic acid | 0.2 | — | 1.79 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 4-nitrobenzoic acid |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 5,8-dihydroxy-1,4-naphthoquinonefixed [NADH] = 100 µM; NADH oxidation followed at 340 nm | 14.3 | — | 695 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 5,8-dihydroxy-1,4-naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 5,8-dihydroxy-1,4-naphthoquinoneping-pong analysis | 16.2 | — | — | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 5,8-dihydroxy-1,4-naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 5-hydroxy-1,4-naphthoquinone | 5.85 | — | 811 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 5-hydroxy-1,4-naphthoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | 9,10-Phenanthrene quinone | 15.55 | — | 755 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), 9,10-Phenanthrene quinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Benzylviologen | 0.5 | — | 3 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Benzylviologen |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Decylubiquinone | 32.1 | — | 2.75 × 10³ | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Decylubiquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Ferricyanide | 6.8 | — | 51 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Ferricyanide |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Idebenone | 41 | — | 2.4 × 10³ | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Idebenone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | NADH | — | — | 1 × 10³ | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), NADH |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Nifuroxime | 1.3 | — | 14 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Nifuroxime |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Nitrobenzene | 0.8 | — | 0.249 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Nitrobenzene |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Nitrofurantoin | 0.6 | — | 2.25 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Nitrofurantoin |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | tetramethyl-1,4-benzoquinone | 13 | — | 412 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), tetramethyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | Trimethyl-aziridinyl-1,4-benzoquinone | 20.9 | — | 144 | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), Trimethyl-aziridinyl-1,4-benzoquinone |
| type II NADH:ubiquinone oxidoreductase (PfNDH2) | Plasmodium falciparum | ubiquinone-1 | 36.7 | — | 1.78 × 10³ | pH 7, 25 °C | PMID 40141152 | Open record: type II NADH:ubiquinone oxidoreductase (PfNDH2), ubiquinone-1 |