EC 1.8.4.12: peptide-methionine (R)-S-oxide reductase

OxidoreductasesOpen in Browse

CatLog read 37 records for EC 1.8.4.12 from 4 papers, for 4 organisms. Names in these papers: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB), methionine sulfoxide reductase B (TcMSRB), methionine sulfoxide reductase B (LinMsrB), MsrB2 and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 17 records for EC 1.8.4.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.4.12 in Browse.

Papers

Papers with records for EC 1.8.4.12
Paper	Organisms	Records
On the functionality of a methionine sulfoxide reductase B from Trypanosoma cruzi	Trypanosoma cruzi	14
Structural Insights into a Bifunctional Peptide Methionine Sulfoxide Reductase MsrA/B Fusion Protein from Helicobacter pylori	Helicobacter pylori	14
The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and…	Arabidopsis thaliana	5
Functional characterization of methionine sulfoxide reductases from Leptospira interrogans	Leptospira interrogans	4

Records

Records for EC 1.8.4.12 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.157	0.05	3.13	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB), dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.17	0.17	1	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB), dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)MsrA domain only (MsrA_D)	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.037	0.25	0.147	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) MsrA domain only (MsrA_D), dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)MsrB domain only (MsrB_D)	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.08	1.7	0.047	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) MsrB domain only (MsrB_D), dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant D197A	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.073	0.06	1.22	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant D197A, dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant D197A	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.102	0.15	0.68	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant D197A, dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E193A	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.078	0.06	1.3	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E193A, dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E193A	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.108	0.14	0.77	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E193A, dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E193A/D197A	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.05	0.05	1	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E193A/D197A, dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E193A/D197A	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.095	0.12	0.78	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E193A/D197A, dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E339A	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.045	0.02	2.25	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E339A, dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant E339A	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.058	0.04	1.47	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant E339A, dabsyl-L-methionine S-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant Y343F	Helicobacter pylori	dabsyl-L-methionine R-sulfoxide	0.087	0.03	2.88	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant Y343F, dabsyl-L-methionine R-sulfoxide
bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB)variant Y343F	Helicobacter pylori	dabsyl-L-methionine S-sulfoxide	0.097	0.12	0.8	pH 7.5, 37 °C	PMID 33807684	Open record: bifunctional peptide methionine sulfoxide reductase MsrA/MsrB fusion protein (HpMsrAB) variant Y343F, dabsyl-L-methionine S-sulfoxide
methionine sulfoxide reductase B (LinMsrB)	Leptospira interrogans	Homo sapiens glutaredoxin 1	0.0145	0.0028	5.2	pH 7, 30 °C	PMID 33242654	Open record: methionine sulfoxide reductase B (LinMsrB), Homo sapiens glutaredoxin 1
methionine sulfoxide reductase B (LinMsrB)	Leptospira interrogans	L-methionine (R)-sulfoxide	0.0077	1	0.008	pH 7, 30 °C	PMID 33242654	Open record: methionine sulfoxide reductase B (LinMsrB), L-methionine (R)-sulfoxide
methionine sulfoxide reductase B (LinMsrB)	Leptospira interrogans	Leptospira interrogans thioredoxin	0.0043	0.026	0.17	pH 7, 30 °C	PMID 33242654	Open record: methionine sulfoxide reductase B (LinMsrB), Leptospira interrogans thioredoxin
methionine sulfoxide reductase B (LinMsrB)	Leptospira interrogans	N-acetyl methionine (R)-sulfoxide	0.0142	0.21	0.067	pH 7, 30 °C	PMID 33242654	Open record: methionine sulfoxide reductase B (LinMsrB), N-acetyl methionine (R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	dihydrotrypanothione (reduced trypanothione, N1,N8-bis(glutathionyl)spermidine)	—	—	0.0024	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), dihydrotrypanothione (reduced trypanothione, N1,N8-bis(glutathionyl)spermidine)
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	L-methionine-(R)-sulfoxide	0.002	1	0.002	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), L-methionine-(R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	MetSO-containing proteins (protein extract of HClO-treated epimastigotes)	0.00122	—	—	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), MetSO-containing proteins (protein extract of HClO-treated epimastigotes)
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	N-acetyl-L-methionine-(R)-sulfoxide	0.0048	0.2	0.024	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), N-acetyl-L-methionine-(R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	Trypanosoma cruzi thioredoxin	0.0057	0.0055	1.03	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), Trypanosoma cruzi thioredoxin
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	Trypanosoma cruzi tryparedoxin I	0.0058	0.0021	2.778	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), Trypanosoma cruzi tryparedoxin I
methionine sulfoxide reductase B (TcMSRB)	Trypanosoma cruzi	Trypanosoma cruzi tryparedoxin II lacking 22 C-terminal residues	0.005	0.003	1.67	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB), Trypanosoma cruzi tryparedoxin II lacking 22 C-terminal residues
methionine sulfoxide reductase B (TcMSRB)variant C72S	Trypanosoma cruzi	N-acetyl-L-methionine-(R)-sulfoxide	5.2 × 10⁻⁴	0.045	0.011	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C72S, N-acetyl-L-methionine-(R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)variant C72S	Trypanosoma cruzi	Trypanosoma cruzi tryparedoxin I	6.7 × 10⁻⁴	0.0016	0.417	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C72S, Trypanosoma cruzi tryparedoxin I
methionine sulfoxide reductase B (TcMSRB)variant C72S/C74S	Trypanosoma cruzi	dihydrotrypanothione (reduced trypanothione, N1,N8-bis(glutathionyl)spermidine)	0.00483	0.204	0.024	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C72S/C74S, dihydrotrypanothione (reduced trypanothione, N1,N8-bis(glutathionyl)spermidine)
methionine sulfoxide reductase B (TcMSRB)variant C72S/C74S	Trypanosoma cruzi	glutathione (reduced)	—	—	1 × 10⁻⁴	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C72S/C74S, glutathione (reduced)
methionine sulfoxide reductase B (TcMSRB)variant C72S/C74S	Trypanosoma cruzi	N-acetyl-L-methionine-(R)-sulfoxide	0.00232	0.043	0.054	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C72S/C74S, N-acetyl-L-methionine-(R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)variant C74S	Trypanosoma cruzi	N-acetyl-L-methionine-(R)-sulfoxide	0.00162	0.047	0.034	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C74S, N-acetyl-L-methionine-(R)-sulfoxide
methionine sulfoxide reductase B (TcMSRB)variant C74S	Trypanosoma cruzi	Trypanosoma cruzi tryparedoxin I	0.00248	0.0019	1.307	pH 7.5, 30 °C	PMID 32682073	Open record: methionine sulfoxide reductase B (TcMSRB) variant C74S, Trypanosoma cruzi tryparedoxin I
MsrB1	Arabidopsis thaliana	dabsyl-MetSO	0.07	0.07853	0.891	pH 8, 37 °C	PMID 15923321	Open record: MsrB1, dabsyl-MetSO
MsrB2	Arabidopsis thaliana	dabsyl-MetSO	0.02	0.05406	0.37	pH 8, 37 °C	PMID 15923321	Open record: MsrB2, dabsyl-MetSO
MsrB2	Arabidopsis thaliana	methionine sulfoxide	1.37	28.98	0.047	pH 8, 30 °C	PMID 15923321	Open record: MsrB2, methionine sulfoxide
MsrB2	Arabidopsis thaliana	N-acetyl-methionine sulfoxide	2.94	2.16	1.361	pH 8, 30 °C	PMID 15923321	Open record: MsrB2, N-acetyl-methionine sulfoxide
MsrB2	Arabidopsis thaliana	poplar thioredoxin h1	—	0.00832	—	pH 8, 30 °C	PMID 15923321	Open record: MsrB2, poplar thioredoxin h1