CatLogenzyme kinetics catalog

EC 2.1.1.135: [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)

TransferasesOpen in Browse

CatLog read 13 records for EC 2.1.1.135 from 1 paper, for 1 organism. Names in these papers: methionine synthase reductase (MSR) variant I22/S175, methionine synthase reductase (MSR) variant M22/S175.

EC 2.1.1.135 is no longer current; BRENDA: “transferred to EC 1.16.1.8”.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

PaperOrganismsRecords
Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductaseHomo sapiens13

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
methionine synthase reductase (MSR) variant I22/S175Homo sapiens2,6-dichloroindophenolTable 20.43——pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiens2,6-dichloroindophenolTable 3—0.0038—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiens3-acetylpyridine adenine dinucleotide phosphate0.86——pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiensdoxorubicinTable 21.61——pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiensdoxorubicinTable 3—0.0286—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiensmenadioneTable 21.61——pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapiensmenadioneTable 3—0.018—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapienspotassium ferricyanideTable 28.24——pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant I22/S175Homo sapienspotassium ferricyanideTable 3—0.774—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant M22/S175Homo sapiens2,6-dichloroindophenol—0.0023—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant M22/S175Homo sapiensdoxorubicin—0.0366—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant M22/S175Homo sapiensmenadione—0.0177—pH 7.5, 37 °CPMID 12416982Open
methionine synthase reductase (MSR) variant M22/S175Homo sapienspotassium ferricyanide—0.663—pH 7.5, 37 °CPMID 12416982Open