EC 2.1.1.20: glycine N-methyltransferase

TransferasesOpen in Browse

CatLog read 26 records for EC 2.1.1.20 from 2 papers, for 1 organism. Names in these papers: glycine N-methyltransferase (GNMT).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 19 records for EC 2.1.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.20 in Browse.

Papers

Papers with records for EC 2.1.1.20
Paper	Organisms	Records
Convergent Mechanistic Features between the Structurally Diverse N- and O-Methyltransferases: Glycine N-Methyltransferase and Catechol O-Methyltransferase	Rattus norvegicus	14
Catalytic mechanism of glycine N-methyltransferase	Rattus norvegicus	12

Records

Records for EC 2.1.1.20 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
glycine N-methyltransferase (GNMT)	Rattus norvegicus	glycine	—	0.43	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT), glycine
glycine N-methyltransferase (GNMT)	Rattus norvegicus	glycine	2.908	1.1	2.616	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT), glycine
glycine N-methyltransferase (GNMT)	Rattus norvegicus	S-adenosyl-L-methionine	0.45	0.036	12 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT), S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)	Rattus norvegicus	S-adenosyl-L-methionine	—	0.108	26.93	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT), S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y194F	Rattus norvegicus	glycine	—	2.8	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y194F, glycine
glycine N-methyltransferase (GNMT)variant Y194F	Rattus norvegicus	S-adenosyl-L-methionine	0.178	0.035	5.1 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y194F, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21A	Rattus norvegicus	glycine	0.0098	26.6	3.7 × 10⁻⁴	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21A, glycine
glycine N-methyltransferase (GNMT)variant Y21A	Rattus norvegicus	S-adenosyl-L-methionine	—	0.539	0.0183	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21A, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21F	Rattus norvegicus	glycine	—	0.24	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y21F, glycine
glycine N-methyltransferase (GNMT)variant Y21F	Rattus norvegicus	glycine	0.42	1.7	0.248	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21F, glycine
glycine N-methyltransferase (GNMT)variant Y21F	Rattus norvegicus	S-adenosyl-L-methionine	0.105	0.042	2.5 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y21F, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21F	Rattus norvegicus	S-adenosyl-L-methionine	—	0.174	2.409	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21F, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21G	Rattus norvegicus	glycine	0.0155	33.6	4.6 × 10⁻⁴	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21G, glycine
glycine N-methyltransferase (GNMT)variant Y21G	Rattus norvegicus	S-adenosyl-L-methionine	—	0.696	0.0223	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21G, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21S	Rattus norvegicus	glycine	0.0108	23.4	4.6 × 10⁻⁴	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21S, glycine
glycine N-methyltransferase (GNMT)variant Y21S	Rattus norvegicus	S-adenosyl-L-methionine	—	0.803	0.0136	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21S, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21T	Rattus norvegicus	glycine	0.0135	22.9	5.9 × 10⁻⁴	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21T, glycine
glycine N-methyltransferase (GNMT)variant Y21T	Rattus norvegicus	S-adenosyl-L-methionine	—	1.136	0.0119	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21T, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y21V	Rattus norvegicus	glycine	0.0097	38.8	2.5 × 10⁻⁴	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21V, glycine
glycine N-methyltransferase (GNMT)variant Y21V	Rattus norvegicus	S-adenosyl-L-methionine	—	0.582	0.0167	pH 7.4, 37 °C	PMID 27355841	Open record: glycine N-methyltransferase (GNMT) variant Y21V, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y220F	Rattus norvegicus	glycine	—	30	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y220F, glycine
glycine N-methyltransferase (GNMT)variant Y220F	Rattus norvegicus	S-adenosyl-L-methionine	0.178	0.014	13 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y220F, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y242F	Rattus norvegicus	glycine	—	0.44	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y242F, glycine
glycine N-methyltransferase (GNMT)variant Y242F	Rattus norvegicus	S-adenosyl-L-methionine	0.47	0.032	15 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y242F, S-adenosyl-L-methionine
glycine N-methyltransferase (GNMT)variant Y33F	Rattus norvegicus	glycine	—	25	—	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y33F, glycine
glycine N-methyltransferase (GNMT)variant Y33F	Rattus norvegicus	S-adenosyl-L-methionine	0.212	0.017	12 calc.	pH 7.2, 30 °C	PMID 12859184	Open record: glycine N-methyltransferase (GNMT) variant Y33F, S-adenosyl-L-methionine