CatLogenzyme kinetics catalog

EC 2.1.1.355: [histone H3]-lysine9 N-trimethyltransferase

TransferasesOpen in Browse

CatLog read 14 records for EC 2.1.1.355 from 1 paper, for 1 organism. Names in these papers: PRDM9 (PR domain-containing protein 9, histone methyltransferase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 2.1.1.355 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.355 in Browse.

Papers

PaperOrganismsRecords
PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 TrimethyltransferaseHomo sapiens14

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 1–25 peptide ART(Kme1)QTARKSTGGKAPRKQLATKAA-GK-biotin (Lys-4 monomethylated)7.360.0051.5 × 10³ calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 1–25 peptide ART(Kme2)QTARKSTGGKAPRKQLATKAA-GK-biotin (Lys-4 dimethylated)5.420.006900 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 1–25 peptide ARTKQTARKSTGGKAPRKQLATKAA-GK-biotin (unmethylated Lys-4)8.420.0042.1 × 10³ calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGV(Kme1)KPHRYRPG-GK-biotin (Lys-36 monomethylated)27 × 10⁻⁴2.9 × 10³ calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGV(Kme2)KPHRYRPG-GK-biotin (Lys-36 dimethylated)9.70.015650 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGVKKPHRYRPG-GK-biotin (unmethylated Lys-36)4.920.0031.6 × 10³ calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)PRDM9 (7 tail) chimeraHomo sapiensS-adenosylmethionine30.024120 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 1–25 peptide ART(Kme1)QTARKSTGGKAPRKQLATKAA-GK-biotin (Lys-4 monomethylated)1.9 × 10⁻⁴4 × 10⁻⁴0.49 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 1–25 peptide ART(Kme2)QTARKSTGGKAPRKQLATKAA-GK-biotin (Lys-4 dimethylated)2.2 × 10⁻⁴1 × 10⁻⁴2.2 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 1–25 peptide ARTKQTARKSTGGKAPRKQLATKAA-GK-biotin (unmethylated Lys-4)1.7 × 10⁻⁴1 × 10⁻⁴1.7 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGV(Kme1)KPHRYRPG-GK-biotin (Lys-36 monomethylated)1.1 × 10⁻⁴3 × 10⁻⁴0.37 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGV(Kme2)KPHRYRPG-GK-biotin (Lys-36 dimethylated)5.6 × 10⁻⁴0.0030.19 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensbiotinylated histone H3 residues 21–44 peptide ATKAARKSAPATGGVKKPHRYRPG-GK-biotin (unmethylated Lys-36)1.4 × 10⁻⁴5 × 10⁻⁴0.28 calc.pH 9, 23 °CPMID 27129774Open
PRDM9 (PR domain-containing protein 9, histone methyltransferase)variant Y357SHomo sapiensS-adenosylmethionine2.2 × 10⁻⁴0.0080.028 calc.pH 9, 23 °CPMID 27129774Open