CatLogenzyme kinetics catalog

EC 2.1.1.366: [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase

TransferasesOpen in Browse

CatLog read 12 records for EC 2.1.1.366 from 1 paper, for 1 organism. Names in these papers: SETDB1, SETDB1:ATF7IP complex (1:1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 1 record for EC 2.1.1.366 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.366 in Browse.

Papers

PaperOrganismsRecords
Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IPHomo sapiens12

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
SETDB1Homo sapienshistone H3 residues 1-15 peptide, K9 dimethylated, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARK(Me2)STGGKA[K-Ahx-biotin])—4.3 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1Homo sapienshistone H3 residues 1-15 peptide, K9 monomethylated, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARK(Me1)STGGKA[K-Ahx-biotin])—5.9 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1Homo sapienshistone H3 residues 1-15 peptide, K9 unmodified, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARKSTGGKA[K-Ahx-biotin])—4.1 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1Homo sapiensS-adenosyl-L-methionineH3K9me0 peptide fixed at its KM; H3K9me0 peptide—6.8 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1Homo sapiensS-adenosyl-L-methionineH3K9me1 peptide fixed at its KM; H3K9me1 peptide—5.6 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1Homo sapiensS-adenosyl-L-methionineH3K9me2 peptide fixed at its KM; H3K9me2 peptide—6.6 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapienshistone H3 residues 1-15 peptide, K9 dimethylated, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARK(Me2)STGGKA[K-Ahx-biotin])—3.9 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapienshistone H3 residues 1-15 peptide, K9 monomethylated, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARK(Me1)STGGKA[K-Ahx-biotin])—4.1 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapienshistone H3 residues 1-15 peptide, K9 unmodified, amide-capped C-terminus, Ahx-biotin on C-terminal lysine (ARTKQTARKSTGGKA[K-Ahx-biotin])—2.8 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapiensS-adenosyl-L-methionineH3K9me0 peptide fixed at its KM; H3K9me0 peptide—5.3 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapiensS-adenosyl-L-methionineH3K9me1 peptide fixed at its KM; H3K9me1 peptide—5.4 × 10⁻⁴—pH 7.6PMID 26813693Open
SETDB1:ATF7IP complex (1:1)Homo sapiensS-adenosyl-L-methionineH3K9me2 peptide fixed at its KM; H3K9me2 peptide—5.2 × 10⁻⁴—pH 7.6PMID 26813693Open