EC 2.1.1.41: sterol 24-C-methyltransferase
TransferasesOpen in Browse
CatLog read 35 records for EC 2.1.1.41 from 3 papers, for 2 organisms. Names in these papers: sterol C24-methyltransferase (Erg6p), sterol methyltransferase (SMT1), sterol methyltransferase (SMT).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 28 records for EC 2.1.1.41 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.41 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis | Saccharomyces cerevisiae | 14 |
| Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols | Glycine max (soybean) | 12 |
| Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis | Saccharomyces cerevisiae | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| sterol C24-methyltransferase (Erg6p) | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 6.7 × 10⁻⁴ | 0.022 | 0.033 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p), 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p) | Saccharomyces cerevisiae | zymosterol | 0.0108 | 0.017 | 0.63 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p), zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81A | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 1.2 × 10⁻⁴ | 0.023 | 0.005 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81A, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81A | Saccharomyces cerevisiae | zymosterol | 8.3 × 10⁻⁴ | 0.018 | 0.05 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81A, zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81F | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 0.0025 | 0.026 | 0.1 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81F, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81F | Saccharomyces cerevisiae | zymosterol | 0.01 | 0.017 | 0.58 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81F, zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81I | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 2.5 × 10⁻⁴ | 0.027 | 0.0083 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81I, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81I | Saccharomyces cerevisiae | zymosterol | 0.0043 | 0.021 | 0.207 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81I, zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81L | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 3.3 × 10⁻⁴ | 0.024 | 0.013 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81L, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81L | Saccharomyces cerevisiae | zymosterol | 0.0042 | 0.018 | 0.23 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81L, zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81V | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 1.2 × 10⁻⁴ | 0.024 | 0.005 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81V, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81V | Saccharomyces cerevisiae | zymosterol | 0.0012 | 0.026 | 0.05 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81V, zymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81W | Saccharomyces cerevisiae | 26,27-dehydrozymosterol | 0.0033 | 0.023 | 0.15 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81W, 26,27-dehydrozymosterol |
| sterol C24-methyltransferase (Erg6p)variant Y81W | Saccharomyces cerevisiae | zymosterol | 0.0133 | 0.017 | 0.78 | pH 7.5, 35 °C | PMID 18555004 | Open record: sterol C24-methyltransferase (Erg6p) variant Y81W, zymosterol |
| sterol methyltransferase (SMT) | Saccharomyces cerevisiae | zymosterol | 0.011 | 0.017 | 0.647 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT), zymosterol |
| sterol methyltransferase (SMT)variant D189L | Saccharomyces cerevisiae | zymosterol | 0.008 | 0.017 | 0.471 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant D189L, zymosterol |
| sterol methyltransferase (SMT)variant E108L | Saccharomyces cerevisiae | zymosterol | 0.002 | 0.034 | 0.059 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant E108L, zymosterol |
| sterol methyltransferase (SMT)variant E209L | Saccharomyces cerevisiae | zymosterol | 0.009 | 0.034 | 0.265 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant E209L, zymosterol |
| sterol methyltransferase (SMT)variant E224L | Saccharomyces cerevisiae | zymosterol | 0.008 | 0.017 | 0.471 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant E224L, zymosterol |
| sterol methyltransferase (SMT)variant E246L | Saccharomyces cerevisiae | zymosterol | 0.002 | 0.042 | 0.048 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant E246L, zymosterol |
| sterol methyltransferase (SMT)variant H107L | Saccharomyces cerevisiae | zymosterol | 0.003 | 0.011 | 0.273 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant H107L, zymosterol |
| sterol methyltransferase (SMT)variant H199L | Saccharomyces cerevisiae | zymosterol | 1 × 10⁻⁴ | 0.024 | 0.004 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant H199L, zymosterol |
| sterol methyltransferase (SMT)variant H238L | Saccharomyces cerevisiae | zymosterol | 0.008 | 0.02 | 0.4 | pH 7.5, 32 °C | PMID 14717613 | Open record: sterol methyltransferase (SMT) variant H238L, zymosterol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 24(28)-Methylenecycloartanol | — | 0.022 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 24(28)-Methylenecycloartanol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 24(28)-Methylenelanosterol | — | 0.02 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 24(28)-Methylenelanosterol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 24(28)-Methylenelophenol | — | 0.03 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 24(28)-Methylenelophenol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 24(28)-methylenelophenol | 0.001 | — | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 24(28)-methylenelophenol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 24-Dehydropollinstanol | — | 0.045 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 24-Dehydropollinstanol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | 31-Norcycloartenol | — | 0.032 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), 31-Norcycloartenol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | Cycloartenol | — | 0.03 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), Cycloartenol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | cycloartenol | 0.01 | — | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), cycloartenol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | Lanosterol | — | 0.027 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), Lanosterol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | Parkeol | — | 0.043 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), Parkeol |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | S-adenosyl-L-methionine | 0.02 | 0.032 | 0.62 calc. | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), S-adenosyl-L-methionine |
| sterol methyltransferase (SMT1) | Glycine max (soybean) | Zymosterol | — | 0.035 | — | pH 7.5, 35 °C | PMID 12807886 | Open record: sterol methyltransferase (SMT1), Zymosterol |