CatLogenzyme kinetics catalog

EC 2.1.1.5: betaine-homocysteine S-methyltransferase

TransferasesOpen in Browse

CatLog read 31 records for EC 2.1.1.5 from 3 papers, for 2 organisms. Names in these papers: betaine-homocysteine S-methyltransferase (BHMT), betaine-homocysteine methyltransferase (BHMT).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 13 records for EC 2.1.1.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.5 in Browse.

Papers

PaperOrganismsRecords
Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferaseRattus norvegicus24
Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferaseHomo sapiens6
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferaseHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
betaine-homocysteine methyltransferase (BHMT)Homo sapiensS-methylmethionine0.006730.0022pH 7.5, 37 °CPMID 18230605Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensbetaine (N,N,N-trimethylglycine)without KCl0.02970.0750.397pH 7.5PMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensbetaine (N,N,N-trimethylglycine)with 150 mM KCl0.04220.05940.711pH 7.5PMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensDL-homocysteinewithout KCl0.03670.3380.108pH 7.5PMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensDL-homocysteinewith 150 mM KCl0.03780.01522.486pH 7.5PMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensDL-homocysteine3.3 × 10⁻⁴2.31.44 × 10⁻⁴pH 7.5, 37 °CPMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Homo sapiensS-methyl-L-methionine0.00443.40.0013pH 7.5, 37 °CPMID 24895213Open
betaine-homocysteine S-methyltransferase (BHMT)Rattus norvegicusglycine betaine—0.3333—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)Rattus norvegicushomocysteine0.0140.10640.13 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant A119GRattus norvegicusglycine betaine—0.3056—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant A119GRattus norvegicushomocysteine0.00750.067980.11 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant C186ARattus norvegicusglycine betaine—0.1852—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant C186ARattus norvegicushomocysteine0.00760.024730.31 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant C186SRattus norvegicusglycine betaine—0.2065—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant C186SRattus norvegicushomocysteine0.0060.074450.081 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant D26ARattus norvegicusglycine betaine—1.174—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant D26ARattus norvegicushomocysteine0.00510.062930.081 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant D26IRattus norvegicushomocysteine0.0021——37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E159GRattus norvegicushomocysteine2.3 × 10⁻⁴——37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E159KRattus norvegicushomocysteine8.2 × 10⁻⁵——37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E21ARattus norvegicusglycine betaine—0.1385—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E21ARattus norvegicushomocysteine0.0060.017470.34 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E21KRattus norvegicusglycine betaine—0.1951—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant E21KRattus norvegicushomocysteine0.0090.072660.12 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant F74ARattus norvegicusglycine betaine—0.9686—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant F74ARattus norvegicushomocysteine0.00720.057440.13 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant T184GRattus norvegicusglycine betaine—0.5481—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant T184GRattus norvegicushomocysteine0.00580.034460.17 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant T73GRattus norvegicusglycine betaine—0.2584—37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant T73GRattus norvegicushomocysteine0.00450.049250.091 calc.37 °CPMID 12487625Open
betaine-homocysteine S-methyltransferase (BHMT)variant Y77ARattus norvegicushomocysteine0.001——37 °CPMID 12487625Open