CatLogenzyme kinetics catalog

EC 2.1.1.77: protein-L-isoaspartate(D-aspartate) O-methyltransferase

TransferasesOpen in Browse

CatLog read 32 records for EC 2.1.1.77 from 3 papers, for 3 organisms. Names in these papers: protein L-isoaspartyl-(D-aspartyl) O-methyltransferase, L-isoaspartyl/D-aspartyl protein methyltransferase isozyme I, protein L-isoaspartyl methyltransferase, protein L-isoaspartyl methyltransferase type II.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 23 records for EC 2.1.1.77 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.77 in Browse.

Papers

PaperOrganismsRecords
Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptidesHomo sapiens, Pyrococcus furiosus16
Identification of isoaspartyl-containing sequences in peptides and proteins that are usually poor substrates for the class II protein carboxyl methyltransferaseHomo sapiens10
Expression, purification, and characterization of the protein repair l-isoaspartyl methyltransferase from Arabidopsis thalianaArabidopsis thaliana6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapienschicken egg white lysozyme containing an L-isoaspartyl linkage at position 101—0.183—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Leu-L-Ser-L-His-L-isoAsp-Gly-L-Tyr-L-Cys-L-Leu—0.0036—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Leu-L-Ser-L-His-L-isoAsp-Gly-L-Tyr-L-cysteic acid-L-Leu—0.017—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Tyr-L-Val-L-Ser-L-isoAsp-Gly-L-Asp-Gly—0.469—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Tyr-L-Val-L-Ser-L-isoAsp-Gly-L-Cys-Gly—0.0046—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Tyr-L-Val-L-Ser-L-isoAsp-Gly-L-cysteic acid-Gly—0.104—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Val-L-Tyr-L-Pro-L-isoAsp-L-Asp-L-Ala—0.0295—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Val-L-Tyr-L-Pro-L-isoAsp-L-Cys-L-Ala—0.0028—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensL-Val-L-Tyr-L-Pro-L-isoAsp-L-cysteic acid-L-Ala—0.175—pH 6, 37 °CPMID 2303443Open
L-isoaspartyl/D-aspartyl protein methyltransferase isozyme IHomo sapiensnative chicken egg white lysozyme—1.081—pH 6, 37 °CPMID 2303443Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaKASA-[L-isoAsp]-LAKY—0.08—pH 7.5, 37 °CPMID 11049748Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaovalbumin—4.95—pH 7.5, 37 °CPMID 11049748Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaovalbumin—1.2—PMID 11049748Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaS-adenosyl-L-methionine—0.006—pH 7.5, 37 °CPMID 11049748Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaVYP-[L-isoAsp]-HA—0.31—pH 7.5, 37 °CPMID 11049748Open
protein L-isoaspartyl methyltransferaseArabidopsis thalianaVYP-L-isoAsp-HA—0.27—PMID 11049748Open
protein L-isoaspartyl methyltransferase type IIHomo sapiensN-Succinyl-AAVA-p-nitroanilide—0.69—pH 7.5, 37 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusKASA-D-Asp-LAKY—0.023—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusKASA-L-isoAsp-LAKY—2.6 × 10⁻⁴—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusKASA-L-isoAsp-LAKY—0.021—pH 4, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusKASA-L-isoAsp-LAKY—5.5 × 10⁻⁴—pH 7.5, 37 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusN-Succinyl-AAVA-p-nitroanilide—0.375—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusN-Succinyl-AAVA-p-nitroanilide—11—pH 4, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusovalbumin (chicken egg, Grade VII)—0.00463—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusovalbumin (chicken egg, Grade VII)—0.166—pH 4, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusovalbumin (chicken egg, Grade VII)—0.0311—pH 7.5, 37 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusS-adenosyl-L-methionine—0.00341—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusS-adenosyl-L-methionine—0.01—pH 4, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusS-adenosyl-L-methionine—9.5 × 10⁻⁴—pH 7.5, 37 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusVYP-L-isoAsp-HA—5.3 × 10⁻⁴—pH 7.5, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusVYP-L-isoAsp-HA—0.008—pH 4, 68 °CPMID 11694513Open
protein L-isoaspartyl-(D-aspartyl) O-methyltransferasePyrococcus furiosusVYP-L-isoAsp-HA—5.9 × 10⁻⁴—pH 7.5, 37 °CPMID 11694513Open