EC 2.1.2.11: 3-methyl-2-oxobutanoate hydroxymethyltransferase
TransferasesOpen in Browse
CatLog read 14 records for EC 2.1.2.11 from 3 papers, for 6 organisms. Names in these papers: ketopantoate hydroxymethyltransferase, ketopantoate hydroxymethyltransferase (Tk-KPHMT, TK0363 protein), BsKPHMT, CgKPHMT and 3 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 5 records for EC 2.1.2.11 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.2.11 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties | Escherichia coli | 7 |
| Rational selection of ketopantoate hydroxymethyltransferase with low product feedback inhibition based on binding free energy calculation analysis | Bacillus subtilis, Corynebacterium glutamicum and 3 more | 5 |
| Identification and characterization of an archaeal ketopantoate reductase and its involvement in regulation of coenzyme A biosynthesis | Thermococcus kodakarensis | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| BsKPHMT | Bacillus subtilis | alpha-ketoisovalerate | 9.7 | 3.22 | 3.01 | pH 7, 37 °C | PMID 42429766 | Open record: BsKPHMT, alpha-ketoisovalerate |
| CgKPHMT | Corynebacterium glutamicum | alpha-ketoisovalerate | 3.88 | 4.4 | 0.88 | pH 7, 37 °C | PMID 42429766 | Open record: CgKPHMT, alpha-ketoisovalerate |
| EcKPHMT | Escherichia coli | alpha-ketoisovalerate | 3.76 | 4 | 0.94 | pH 7, 37 °C | PMID 42429766 | Open record: EcKPHMT, alpha-ketoisovalerate |
| EpKPHMT | Enterovibrio pacificus | alpha-ketoisovalerate | 8.7 | 2.92 | 2.97 | pH 7, 37 °C | PMID 42429766 | Open record: EpKPHMT, alpha-ketoisovalerate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | alpha-keto-beta-methylvalerate | — | 5.9 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, alpha-keto-beta-methylvalerate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | alpha-ketobutyrate | — | 2.9 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, alpha-ketobutyrate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | alpha-ketoisovalerateReaction 1f (ketopantoate synthesis) | — | 1.1 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, alpha-ketoisovalerate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | alpha-ketoisovalerateketo acid varied | — | 1 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, alpha-ketoisovalerate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | alpha-ketovalerate | — | 25 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, alpha-ketovalerate |
| ketopantoate hydroxymethyltransferase | Escherichia coli | formaldehyde | — | 5.9 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, formaldehyde |
| ketopantoate hydroxymethyltransferase | Escherichia coli | tetrahydrofolate | — | 0.16 | — | pH 6.8, 37 °C | PMID 6463 | Open record: ketopantoate hydroxymethyltransferase, tetrahydrofolate |
| ketopantoate hydroxymethyltransferase (Tk-KPHMT, TK0363 protein) | Thermococcus kodakarensis | 2-oxoisovalerate | 0.76 | 4.73 | 0.16 calc. | pH 6.5, 85 °C | PMID 23941541 | Open record: ketopantoate hydroxymethyltransferase (Tk-KPHMT, TK0363 protein), 2-oxoisovalerate |
| ketopantoate hydroxymethyltransferase (Tk-KPHMT, TK0363 protein) | Thermococcus kodakarensis | formaldehyde | 1.97 | 4.92 | 0.400 calc. | pH 6.5, 85 °C | PMID 23941541 | Open record: ketopantoate hydroxymethyltransferase (Tk-KPHMT, TK0363 protein), formaldehyde |
| MpKPHMT | Mangrovibacter plantisponsor | alpha-ketoisovalerate | 6.33 | 1.2 | 5.28 | pH 7, 37 °C | PMID 42429766 | Open record: MpKPHMT, alpha-ketoisovalerate |