EC 2.3.1.137: carnitine O-octanoyltransferase
TransferasesOpen in Browse
CatLog read 43 records for EC 2.3.1.137 from 3 papers, for 3 organisms. Names in these papers: carnitine acetyltransferase (CrAT), human peroxisomal carnitine O-acetyltransferase (hpCAT).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 12 records for EC 2.3.1.137 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.137 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Redesign of carnitine acetyltransferase specificity by protein engineering | Rattus norvegicus (rat) | 20 |
| Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase | Homo sapiens | 14 |
| Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates | Mus musculus | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| carnitine acetyltransferase (CrAT) | Mus musculus | acetyl-coenzyme A | 97.6 | 0.021 | 4.7 × 10³ | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT), acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT) | Mus musculus | hexanoyl-coenzyme A | 30.4 | 0.1034 | 290 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT), hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant H343E | Mus musculus | acetyl-coenzyme A | 15.4 | 0.0324 | 480 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant H343E, acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Mus musculus | acetyl-coenzyme A | 28.4 | 0.0746 | 380 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant M564G, acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Mus musculus | hexanoyl-coenzyme A | 204.7 | 0.0224 | 9.1 × 10³ | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant M564G, hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant S554A | Mus musculus | acetyl-coenzyme A | 4 | 0.0921 | 43 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant S554A, acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant S554A | Mus musculus | hexanoyl-coenzyme A | 1.42 | 0.0415 | 34 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant S554A, hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant S554A/M564G | Mus musculus | acetyl-coenzyme A | 1.4 | 0.0596 | 24 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant S554A/M564G, acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant S554A/M564G | Mus musculus | hexanoyl-coenzyme A | 8.2 | 0.1118 | 73 | pH 7.8 | PMID 16870616 | Open record: carnitine acetyltransferase (CrAT) variant S554A/M564G, hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | acetyl-coenzyme A | — | 0.0228 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | butyryl-coenzyme A | — | 0.0307 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), butyryl-coenzyme A |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | hexanoyl-coenzyme A | — | 0.0332 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | L-carnitinecosubstrate acetyl-CoA | — | 0.203 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), L-carnitine |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | L-carnitinecosubstrate butyryl-CoA | — | 0.22 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), L-carnitine |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | L-carnitinecosubstrate hexanoyl-CoA | — | 0.567 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), L-carnitine |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | L-carnitinecosubstrate octanoyl-CoA | — | 0.964 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), L-carnitine |
| carnitine acetyltransferase (CrAT) | Rattus norvegicus (rat) | octanoyl-coenzyme A | — | 0.0247 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT), octanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | acetyl-coenzyme A | — | 0.0317 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, acetyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | butyryl-coenzyme A | — | 0.0148 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, butyryl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | decanoyl-coenzyme A | — | 0.0108 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, decanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | hexanoyl-coenzyme A | — | 0.0223 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, hexanoyl-coenzyme A |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate acetyl-CoA | — | 0.339 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate butyryl-CoA | — | 0.17 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate hexanoyl-CoA | — | 0.164 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate octanoyl-CoA | — | 0.086 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate decanoyl-CoA | — | 0.0269 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | L-carnitinecosubstrate myristoyl-CoA | — | 0.309 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, L-carnitine |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | myristoyl-coenzyme A (tetradecanoyl-CoA) | — | 0.0127 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, myristoyl-coenzyme A (tetradecanoyl-CoA) |
| carnitine acetyltransferase (CrAT)variant M564G | Rattus norvegicus (rat) | octanoyl-coenzyme A | — | 0.0109 | — | pH 7.8, 30 °C | PMID 15155769 | Open record: carnitine acetyltransferase (CrAT) variant M564G, octanoyl-coenzyme A |
| human peroxisomal carnitine O-acetyltransferase (hpCAT) | Homo sapiens | acetyl-CoA | — | 0.0423 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT), acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT) | Homo sapiens | L-carnitine | 38.5 | 0.11 | 350 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT), L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant F545A | Homo sapiens | acetyl-CoA | — | 0.1779 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant F545A, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant F545A | Homo sapiens | L-carnitine | 8.57 | 2 | 4.3 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant F545A, L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant F545Y | Homo sapiens | acetyl-CoA | — | 0.0637 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant F545Y, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant F545Y | Homo sapiens | L-carnitine | 30.5 | 0.15 | 200 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant F545Y, L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant R497Q | Homo sapiens | acetyl-CoA | — | 0.1202 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant R497Q, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant R497Q | Homo sapiens | L-carnitine | 94.8 | 25.6 | 3.7 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant R497Q, L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant T444A | Homo sapiens | acetyl-CoA | — | 0.1883 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant T444A, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant T444A | Homo sapiens | L-carnitine | 5.76 | 7.5 | 0.77 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant T444A, L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant Y431A | Homo sapiens | acetyl-CoA | — | 0.0871 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant Y431A, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant Y431A | Homo sapiens | L-carnitine | 44.2 | 11.1 | 4 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant Y431A, L-carnitine |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant Y431F | Homo sapiens | acetyl-CoA | — | 0.4979 | — | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant Y431F, acetyl-CoA |
| human peroxisomal carnitine O-acetyltransferase (hpCAT)variant Y431F | Homo sapiens | L-carnitine | 0.78 | 35.9 | 0.022 | pH 8 | PMID 15099582 | Open record: human peroxisomal carnitine O-acetyltransferase (hpCAT) variant Y431F, L-carnitine |