EC 2.3.1.300: branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase
TransferasesOpen in Browse
CatLog read 15 records for EC 2.3.1.300 from 2 papers, for 2 organisms. Names in these papers: FabH (beta-ketoacyl-acyl carrier protein synthase III), beta-ketoacyl-acyl carrier protein synthase III (FabH).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 4 records for EC 2.3.1.300 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.300 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Streptomyces coelicolor RedP and FabH enzymes, initiating undecylprodiginine and fatty acid biosynthesis, exhibit distinct acyl-CoA and malonyl-acyl carrier protein substrate specificities | Streptomyces coelicolor | 8 |
| FabH selectivity for anteiso branched-chain fatty acid precursors in low-temperature adaptation in Listeria monocytogenes | Listeria monocytogenes | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | 2-methylbutyryl-CoA | 0.458 | 0.011 | 42 | pH 7, 30 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), 2-methylbutyryl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | 2-methylbutyryl-CoA | 0.047 | 0.0063 | 6.7 | pH 7, 10 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), 2-methylbutyryl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | Acetyl-CoA | 6.7 × 10⁻⁴ | 0.0985 | 0.0068 calc. | pH 7, 30 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), Acetyl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | Isobutyryl-CoA | 0.317 | 0.0243 | 13 | pH 7, 30 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), Isobutyryl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | Isobutyryl-CoA | 0.102 | 0.0307 | 3.3 | pH 7, 10 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), Isobutyryl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | Isovaleryl-CoA | 0.12 | 0.0053 | 23 | pH 7, 30 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), Isovaleryl-CoA |
| beta-ketoacyl-acyl carrier protein synthase III (FabH) | Listeria monocytogenes | Isovaleryl-CoA | 0.018 | 0.0169 | 1.7 | pH 7, 10 °C | PMID 19863661 | Open record: beta-ketoacyl-acyl carrier protein synthase III (FabH), Isovaleryl-CoA |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | acetyl-CoAfixed malonyl-FabC 30 µM; cosubstrate malonyl-FabC | 0.0287 | 0.00836 | 3.3 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), acetyl-CoA |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | acetyl-CoAfixed malonyl-RedQ 30 µM; cosubstrate malonyl-RedQ | 0.0012 | 0.00713 | 0.17 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), acetyl-CoA |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | isobutyryl-CoAfixed malonyl-FabC 30 µM; cosubstrate malonyl-FabC | 0.2862 | 0.00174 | 164 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), isobutyryl-CoA |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | isobutyryl-CoAfixed malonyl-RedQ 30 µM; cosubstrate malonyl-RedQ | 0.011 | 0.00166 | 6.7 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), isobutyryl-CoA |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | malonyl-[acyl-carrier protein] (S. coelicolor FabC, the fatty acid synthase ACP)isobutyryl-CoA 10 µM [1-14C]isobutyryl-CoA | 0.3388 | 0.00453 | 80.7 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), malonyl-[acyl-carrier protein] (S. coelicolor FabC, the fatty acid synthase ACP) |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | malonyl-[acyl-carrier protein] (S. coelicolor FabC, the fatty acid synthase ACP)acetyl-CoA 30 µM [1-14C]acetyl-CoA; cosubstrate acetyl-CoA | 0.0428 | 0.00411 | 11 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), malonyl-[acyl-carrier protein] (S. coelicolor FabC, the fatty acid synthase ACP) |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | malonyl-[acyl-carrier protein] (S. coelicolor RedQ, the prodiginine-cluster ACP)isobutyryl-CoA 10 µM [1-14C]isobutyryl-CoA | 0.019 | 0.0078 | 2.3 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), malonyl-[acyl-carrier protein] (S. coelicolor RedQ, the prodiginine-cluster ACP) |
| FabH (beta-ketoacyl-acyl carrier protein synthase III) | Streptomyces coelicolor | malonyl-[acyl-carrier protein] (S. coelicolor RedQ, the prodiginine-cluster ACP)acetyl-CoA 30 µM [1-14C]acetyl-CoA; cosubstrate acetyl-CoA | 0.0022 | 0.00793 | 0.28 | pH 7.2, 30 °C | PMID 22136753 | Open record: FabH (beta-ketoacyl-acyl carrier protein synthase III), malonyl-[acyl-carrier protein] (S. coelicolor RedQ, the prodiginine-cluster ACP) |