EC 2.3.1.50: serine C-palmitoyltransferase
TransferasesOpen in Browse
CatLog read 33 records for EC 2.3.1.50 from 3 papers, for 1 organism. Names in these papers: serine palmitoyltransferase (SPT), serine palmitoyltransferase (SpSPTase), serine palmitoyltransferase (Sp SPT).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 25 records for EC 2.3.1.50 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.50 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics | Sphingomonas paucimobilis | 17 |
| Semi-rational approach to expand the Acyl-CoA Chain length tolerance of Sphingomonas paucimobilis serine palmitoyltransferase | Sphingomonas paucimobilis | 10 |
| The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations | Sphingomonas paucimobilis | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| serine palmitoyltransferase (Sp SPT) | Sphingomonas paucimobilis | L-serine | 1.14 | 1.6 | 0.712 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT), L-serine | |
| serine palmitoyltransferase (Sp SPT) | Sphingomonas paucimobilis | palmitoyl coenzyme A | — | 0.0356 | 32.02 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT), palmitoyl coenzyme A | |
| serine palmitoyltransferase (Sp SPT)variant G385F | Sphingomonas paucimobilis | L-serine | 0.41 | 3 | 0.136 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT) variant G385F, L-serine | |
| serine palmitoyltransferase (Sp SPT)variant G385F | Sphingomonas paucimobilis | palmitoyl coenzyme A | — | 0.0522 | 7.854 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT) variant G385F, palmitoyl coenzyme A | |
| serine palmitoyltransferase (Sp SPT)variant V246M | Sphingomonas paucimobilis | L-serine | 0.44 | 2.5 | 0.176 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT) variant V246M, L-serine | |
| serine palmitoyltransferase (Sp SPT)variant V246M | Sphingomonas paucimobilis | palmitoyl coenzyme A | — | 0.128 | 3.437 | PMID 24175284 | Open record: serine palmitoyltransferase (Sp SPT) variant V246M, palmitoyl coenzyme A | |
| serine palmitoyltransferase (SpSPTase) | Sphingomonas paucimobilis | dodecanoyl-CoA | 0.11 | 0.25 | 0.44 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase), dodecanoyl-CoA |
| serine palmitoyltransferase (SpSPTase) | Sphingomonas paucimobilis | L-serine | — | 7.2 | — | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase), L-serine |
| serine palmitoyltransferase (SpSPTase) | Sphingomonas paucimobilis | n-C10-CoA | 0.034 | 0.68 | 0.05 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase), n-C10-CoA |
| serine palmitoyltransferase (SpSPTase) | Sphingomonas paucimobilis | n-C14-CoA | 0.76 | 0.08 | 9.5 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase), n-C14-CoA |
| serine palmitoyltransferase (SpSPTase) | Sphingomonas paucimobilis | palmitoyl-CoA | 0.85 | 0.041 | 21 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase), palmitoyl-CoA |
| serine palmitoyltransferase (SpSPTase)variant R378K | Sphingomonas paucimobilis | dodecanoyl-CoA | 0.35 | 0.56 | 0.625 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase) variant R378K, dodecanoyl-CoA |
| serine palmitoyltransferase (SpSPTase)variant R378K | Sphingomonas paucimobilis | L-serine | — | 5.6 | — | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase) variant R378K, L-serine |
| serine palmitoyltransferase (SpSPTase)variant R378K | Sphingomonas paucimobilis | n-C10-CoA | 0.13 | 0.9 | 0.14 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase) variant R378K, n-C10-CoA |
| serine palmitoyltransferase (SpSPTase)variant R378K | Sphingomonas paucimobilis | n-C14-CoA | 0.19 | 0.097 | 2 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase) variant R378K, n-C14-CoA |
| serine palmitoyltransferase (SpSPTase)variant R378K | Sphingomonas paucimobilis | palmitoyl-CoA | 0.12 | 0.024 | 5 | pH 7.5, 25 °C | PMID 32423667 | Open record: serine palmitoyltransferase (SpSPTase) variant R378K, palmitoyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | arachidoyl-CoA | 0.327 | — | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), arachidoyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | decanoyl-CoA | 0.045 | 2.325 | 0.0194 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), decanoyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | L-serine | 1.15 | 1.4 | 0.8214 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), L-serine |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | lauroyl-CoA | 0.262 | 0.8222 | 0.3187 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), lauroyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | myristoyl-CoA | 0.601 | 0.0971 | 6.189 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), myristoyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | palmitoyl-CoA | 1.15 | 0.0354 | 32.49 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), palmitoyl-CoA |
| serine palmitoyltransferase (SPT) | Sphingomonas paucimobilis | stearoyl-CoA | 0.898 | 0.0137 | 65.55 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT), stearoyl-CoA |
| serine palmitoyltransferase (SPT)variant N100C | Sphingomonas paucimobilis | L-serine | 0.25 | 7 | 0.0357 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100C, L-serine |
| serine palmitoyltransferase (SPT)variant N100C | Sphingomonas paucimobilis | palmitoyl-CoA | — | 0.06 | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100C, palmitoyl-CoA |
| serine palmitoyltransferase (SPT)variant N100W | Sphingomonas paucimobilis | L-serine | 0.009 | 1.6 | 0.0056 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100W, L-serine |
| serine palmitoyltransferase (SPT)variant N100W | Sphingomonas paucimobilis | palmitoyl-CoA | — | 0.0193 | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100W, palmitoyl-CoA |
| serine palmitoyltransferase (SPT)variant N100Y | Sphingomonas paucimobilis | L-serine | 0.005 | 2.5 | 0.002 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100Y, L-serine |
| serine palmitoyltransferase (SPT)variant N100Y | Sphingomonas paucimobilis | palmitoyl-CoA | — | 0.0314 | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant N100Y, palmitoyl-CoA |
| serine palmitoyltransferase (SPT)variant R378A | Sphingomonas paucimobilis | L-serine | 0.0783 | 3.8 | 0.0205 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant R378A, L-serine |
| serine palmitoyltransferase (SPT)variant R378A | Sphingomonas paucimobilis | palmitoyl-CoA | — | 0.0392 | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant R378A, palmitoyl-CoA |
| serine palmitoyltransferase (SPT)variant R378N | Sphingomonas paucimobilis | L-serine | 0.033 | 2.4 | 0.0138 | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant R378N, L-serine |
| serine palmitoyltransferase (SPT)variant R378N | Sphingomonas paucimobilis | palmitoyl-CoA | — | 0.031 | — | pH 7.5 | PMID 19376777 | Open record: serine palmitoyltransferase (SPT) variant R378N, palmitoyl-CoA |