EC 2.3.1.97: glycylpeptide N-tetradecanoyltransferase

TransferasesOpen in Browse

CatLog read 13 records for EC 2.3.1.97 from 2 papers, for 3 organisms. Names in these papers: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1), myristoyl-CoA:protein N-myristoyltransferase (LmNMT), myristoyl-CoA:protein N-myristoyltransferase (TbNMT).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 42 records for EC 2.3.1.97 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.97 in Browse.

Papers

Papers with records for EC 2.3.1.97
Paper	Organisms	Records
High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation	Homo sapiens	9
Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major	Leishmania major, Trypanosoma brucei	4

Records

Records for EC 2.3.1.97 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
myristoyl-CoA:protein N-myristoyltransferase (LmNMT)	Leishmania major	Gly-Gln-Leu-Phe-Thr-Ser-Arg-Arg	24	0.11	219	pH 7.4, 30 °C	PMID 16480339	Open record: myristoyl-CoA:protein N-myristoyltransferase (LmNMT), Gly-Gln-Leu-Phe-Thr-Ser-Arg-Arg
myristoyl-CoA:protein N-myristoyltransferase (LmNMT)	Leishmania major	myristoyl-CoA	23.6	0.00137	1.722 × 10⁴	pH 7.4, 30 °C	PMID 16480339	Open record: myristoyl-CoA:protein N-myristoyltransferase (LmNMT), myristoyl-CoA
myristoyl-CoA:protein N-myristoyltransferase (TbNMT)	Trypanosoma brucei	Gly-Cys-Gly-Gly-Ser-Lys-Val-Lys	18.2	0.0113	1.61 × 10³	pH 7.4, 30 °C	PMID 16480339	Open record: myristoyl-CoA:protein N-myristoyltransferase (TbNMT), Gly-Cys-Gly-Gly-Ser-Lys-Val-Lys
myristoyl-CoA:protein N-myristoyltransferase (TbNMT)	Trypanosoma brucei	myristoyl-CoA	76.8	0.00178	4.32 × 10⁴	pH 7.4, 30 °C	PMID 16480339	Open record: myristoyl-CoA:protein N-myristoyltransferase (TbNMT), myristoyl-CoA
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.41	0.018	23.50	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1), Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant K107E/K252E	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	1.33	0.051	25.85	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant K107E/K252E, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant V181A	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.36	0.02	18.54	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant V181A, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant V181L	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.33	0.054	6.172	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant V181L, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant Y180A	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.16	0.765	0.206	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant Y180A, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant Y180F/N246A	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.68	0.033	20.92	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant Y180F/N246A, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant Y192A	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.93	0.187	4.96	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant Y192A, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant ΔC2	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.34	0.629	0.538	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant ΔC2, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)
N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1)variant ΔC3	Homo sapiens	Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)	0.22	2.14	0.093	pH 8, 30 °C	PMID 32111831	Open record: N-myristoyltransferase 1 (HsNMT1, glycylpeptide N-tetradecanoyltransferase 1) variant ΔC3, Gly-Cys-Ser-Val-Ser-Lys-Lys-Lys (GCSVSKKK)