CatLogenzyme kinetics catalog

EC 2.3.2.12: peptidyltransferase

TransferasesOpen in Browse

CatLog read 8 records for EC 2.3.2.12 from 1 paper, for 1 organism. Names in these papers: ribosomal peptidyltransferase (70S ribosome, 23S rRNA).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 5 records for EC 2.3.2.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.2.12 in Browse.

Papers

PaperOrganismsRecords
Catalytic properties of mutant 23 S ribosomes resistant to oxazolidinonesEscherichia coli8

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)Escherichia coliN-formylmethionyl-tRNAiMet (initiator tRNA)—5.4 × 10⁻⁵—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)Escherichia colipuromycin—0.0169—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant A2058GEscherichia coliN-formylmethionyl-tRNAiMet (initiator tRNA)—1.8 × 10⁻⁴—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant A2058GEscherichia colipuromycin—0.0127—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant G2032AEscherichia coliN-formylmethionyl-tRNAiMet (initiator tRNA)—6.2 × 10⁻⁵—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant G2032AEscherichia colipuromycin—0.0209—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant G2447AEscherichia coliN-formylmethionyl-tRNAiMet (initiator tRNA)—2.47 × 10⁻⁴—pH 7.4PMID 12645571Open
ribosomal peptidyltransferase (70S ribosome, 23S rRNA)variant G2447AEscherichia colipuromycin—0.0351—pH 7.4PMID 12645571Open