EC 2.4.1.288: galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase
TransferasesOpen in Browse
CatLog read 27 records for EC 2.4.1.288 from 4 papers, for 2 organisms. Names in these papers: GlfT2 (bifunctional galactofuranosyltransferase), GlfT2, GlfT2 (galactofuranosyltransferase), LPG1L and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 2 records for EC 2.4.1.288 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.1.288 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan | Mycobacterium tuberculosis | 8 |
| Synthetic UDP-galactofuranose analogs reveal critical enzyme-substrate interactions in GlfT2-catalyzed mycobacterial galactan assembly | — | 7 |
| The LPG1x family from Leishmania major is constituted of rare eukaryotic galactofuranosyltransferases with unprecedented catalytic properties | Leishmania major | 7 |
| Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase | Mycobacterium tuberculosis | 5 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| GlfT2 | — | dTDP-galactofuranose | 1.62 | 1.9 | 0.33 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, dTDP-galactofuranose |
| GlfT2 | — | UDP-5-deoxy-galactofuranose | 0.17 | 0.9 | 0.2 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, UDP-5-deoxy-galactofuranose |
| GlfT2 | — | UDP-6-deoxy-galactofuranose | 1.32 | 1 | 1.2 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, UDP-6-deoxy-galactofuranose |
| GlfT2 | — | UDP-galactofuranose2 fixed; β-Galf-(1→5)-β-Galf-(1→6)-β-Galf-octyl (acceptor 2) | 2.18 | 0.25 | 8.3 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, UDP-galactofuranose |
| GlfT2 | — | UDP-galactofuranose3 fixed; β-Galf-(1→6)-β-Galf-(1→5)-β-Galf-octyl (acceptor 3) | 0.33 | — | — | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, UDP-galactofuranose |
| GlfT2 | — | UDP-L-arabinofuranose | 0.245 | 0.9 | 0.25 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, UDP-L-arabinofuranose |
| GlfT2 | — | uridine 5'-diphospho-3''-deoxy-alpha-D-xylo-hexofuranose | 0.02 | 0.5 | 0.037 | pH 7.6, 37 °C | PMID 22499274 | Open record: GlfT2, uridine 5'-diphospho-3''-deoxy-alpha-D-xylo-hexofuranose |
| GlfT2 (bifunctional galactofuranosyltransferase) | Mycobacterium tuberculosis | octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) | 7.17 | 0.6 | 12 calc. | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase), octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) |
| GlfT2 (bifunctional galactofuranosyltransferase) | Mycobacterium tuberculosis | UDP-alpha-D-galactofuranose | — | 0.38 | — | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase), UDP-alpha-D-galactofuranose |
| GlfT2 (bifunctional galactofuranosyltransferase)variant E300S | Mycobacterium tuberculosis | octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) | 0.005 | 1.78 | 0.0028 calc. | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant E300S, octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) |
| GlfT2 (bifunctional galactofuranosyltransferase)variant E300S | Mycobacterium tuberculosis | UDP-alpha-D-galactofuranose | — | 0.42 | — | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant E300S, UDP-alpha-D-galactofuranose |
| GlfT2 (bifunctional galactofuranosyltransferase)variant H413S | Mycobacterium tuberculosis | octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) | 0.0042 | 1.54 | 0.0027 calc. | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant H413S, octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) |
| GlfT2 (bifunctional galactofuranosyltransferase)variant H413S | Mycobacterium tuberculosis | UDP-alpha-D-galactofuranose | — | 0.43 | — | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant H413S, UDP-alpha-D-galactofuranose |
| GlfT2 (bifunctional galactofuranosyltransferase)variant W399S | Mycobacterium tuberculosis | octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) | 0.0058 | 1.78 | 0.0033 calc. | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant W399S, octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside (acceptor 1) |
| GlfT2 (bifunctional galactofuranosyltransferase)variant W399S | Mycobacterium tuberculosis | UDP-alpha-D-galactofuranose | — | 0.41 | — | pH 7.6, 37 °C | PMID 22707726 | Open record: GlfT2 (bifunctional galactofuranosyltransferase) variant W399S, UDP-alpha-D-galactofuranose |
| GlfT2 (galactofuranosyltransferase) | Mycobacterium tuberculosis | 4 Galf(1–5)Galf(1–6)Galf | 3.7 | 0.013 | 280 | PMID 27302377 | Open record: GlfT2 (galactofuranosyltransferase), 4 Galf(1–5)Galf(1–6)Galf | |
| GlfT2 (galactofuranosyltransferase) | Mycobacterium tuberculosis | 5 Galf(1–6)Galf(1–5)Galf | 0.72 | 0.19 | 3.8 | PMID 27302377 | Open record: GlfT2 (galactofuranosyltransferase), 5 Galf(1–6)Galf(1–5)Galf | |
| GlfT2 (galactofuranosyltransferase) | Mycobacterium tuberculosis | 6 Galf(1–6)Galf(1–6)Galf | 5.3 | 0.034 | 160 | PMID 27302377 | Open record: GlfT2 (galactofuranosyltransferase), 6 Galf(1–6)Galf(1–6)Galf | |
| GlfT2 (galactofuranosyltransferase) | Mycobacterium tuberculosis | 7 Galf(1–5)Galf(1–5)Galf | 0.87 | 0.029 | 30 | PMID 27302377 | Open record: GlfT2 (galactofuranosyltransferase), 7 Galf(1–5)Galf(1–5)Galf | |
| GlfT2 (galactofuranosyltransferase) | Mycobacterium tuberculosis | 8 Tetrasaccharide | 2.9 | 0.013 | 220 | PMID 27302377 | Open record: GlfT2 (galactofuranosyltransferase), 8 Tetrasaccharide | |
| LPG1 | Leishmania major | uridine 5'-diphospho-α-D-galactofuranose | 512.5 | 0.07 | 6.8 × 10³ | PMID 30514885 | Open record: LPG1, uridine 5'-diphospho-α-D-galactofuranose | |
| LPG1 | Leishmania major | uridine 5'-diphospho-α-D-galactopyranose | 5.33 | 0.23 | 23 | PMID 30514885 | Open record: LPG1, uridine 5'-diphospho-α-D-galactopyranose | |
| LPG1L | Leishmania major | guanosine 5'-diphospho-α-D-glucopyranose | 0.4 | 0.043 | 8.3 | PMID 30514885 | Open record: LPG1L, guanosine 5'-diphospho-α-D-glucopyranose | |
| LPG1L | Leishmania major | guanosine 5'-diphospho-α-D-mannopyranose | 1.43 | 0.032 | 47.7 | PMID 30514885 | Open record: LPG1L, guanosine 5'-diphospho-α-D-mannopyranose | |
| LPG1L | Leishmania major | uridine 5'-diphospho-α-D-galactofuranose | 88.27 | 0.02 | 4847 | PMID 30514885 | Open record: LPG1L, uridine 5'-diphospho-α-D-galactofuranose | |
| LPG1L | Leishmania major | uridine 5'-diphospho-α-D-galactopyranose | 7.8 | 0.05 | 165 | PMID 30514885 | Open record: LPG1L, uridine 5'-diphospho-α-D-galactopyranose | |
| LPG1L | Leishmania major | uridine 5'-diphospho-α-D-glucopyranose | 3.42 | 0.006 | 578 | PMID 30514885 | Open record: LPG1L, uridine 5'-diphospho-α-D-glucopyranose |