CatLogenzyme kinetics catalog

EC 2.4.1.41: polypeptide N-acetylgalactosaminyltransferase

TransferasesOpen in Browse

CatLog read 61 records for EC 2.4.1.41 from 4 papers, for 2 organisms. Names in these papers: ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2), ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10), pp-GalNAc-T13, GalNAc-T1 and 10 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 65 records for EC 2.4.1.41 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.1.41 in Browse.

Papers

PaperOrganismsRecords
The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selectionHomo sapiens22
UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family treeHomo sapiens17
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and…Homo sapiens12
Polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) isozyme surface charge governs charge substrate preferences to modulate mucin type O-glycosylationHomo sapiens, Taeniopygia guttata10

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
GalNAc-T1Homo sapiensEA2 peptide PTTDSTTPAPTTK—0.075—37 °CPMID 22186971Open
GalNAc-T1Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-13—0.46—37 °CPMID 22186971Open
GalNAc-T1Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-3—0.332—37 °CPMID 22186971Open
GalNAc-T1Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-3 and Thr-13—0.206—37 °CPMID 22186971Open
GalNAc-T1Homo sapiensMUC5AC peptide GTTPSPVPTTSTTSAP—0.171—37 °CPMID 22186971Open
GalNAc-T12 (polypeptide N-acetylgalactosaminyltransferase 12)Homo sapiensGAGADDDYAVTPGPGAGAGAG0.6020.5761.04 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T12 (polypeptide N-acetylgalactosaminyltransferase 12)Homo sapiensGAGADDDYAVTPGPRRRAGAG0.5680.41.4 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T12 (polypeptide N-acetylgalactosaminyltransferase 12)Homo sapiensGAGAGAGYAVTPGPRRRAGAG0.2080.1561.34 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T13Homo sapiensEA2 peptide PTTDSTTPAPTTK—0.124—37 °CPMID 22186971Open
GalNAc-T13Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-13—0.353—37 °CPMID 22186971Open
GalNAc-T13Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-3—0.263—37 °CPMID 22186971Open
GalNAc-T13Homo sapiensMUC5AC peptide GTTPSPVPTTSTTSAP—0.111—37 °CPMID 22186971Open
GalNAc-T13-V1Homo sapiensEA2 peptide PTTDSTTPAPTTK—0.108—37 °CPMID 22186971Open
GalNAc-T13-V1Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-13—0.13—37 °CPMID 22186971Open
GalNAc-T13-V1Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-3—0.035—37 °CPMID 22186971Open
GalNAc-T13-V1Homo sapiensMUC5AC peptide GTTPSPVPTTSTTSAP—0.067—37 °CPMID 22186971Open
GalNAc-T16Homo sapiensEA2 peptide PTTDSTTPAPTTK—0.172—37 °CPMID 22186971Open
GalNAc-T16Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-13—0.115—37 °CPMID 22186971Open
GalNAc-T16Homo sapiensMUC5AC glycopeptide GTTPSPVPTTSTTSAP carrying α-GalNAc at Thr-3—0.299—37 °CPMID 22186971Open
GalNAc-T16Homo sapiensMUC5AC peptide GTTPSPVPTTSTTSAP—0.344—37 °CPMID 22186971Open
GalNAc-T2 (polypeptide N-acetylgalactosaminyltransferase 2)Homo sapiensGAGADDDYAVTPGPDDDAGAG0.8922.590.344 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T2 (polypeptide N-acetylgalactosaminyltransferase 2)Homo sapiensGAGAGAGYAVTPGPGAGAGAG1.3025.420.240 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T5 (polypeptide N-acetylgalactosaminyltransferase 5)Homo sapiensGAGAGAGYAVTPGPRRRAGAG4.421.522.91 calc.pH 6.8, 37 °CPMID 37555669Open
GalNAc-T5 (polypeptide N-acetylgalactosaminyltransferase 5)Homo sapiensGAGARRRYAVTPGPRRRAGAG20.6293.2 calc.pH 6.8, 37 °CPMID 37555669Open
pp-GalNAc-T1Homo sapiensFAM-AHGVTSAPDTR (5-carboxyfluorescein-labeled peptide)—0.23—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T1Homo sapiensGPTEVAQTPTPETFLTTIK-FAM (5-carboxyfluorescein-labeled peptide)—0.19—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T1Homo sapiensPTPSATTPAPPSSSAPPETTAAK-FAM (5-carboxyfluorescein-labeled peptide)—0.054—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensATTAATSTGDPTVAK-FAM (5-carboxyfluorescein-labeled peptide)—0.38—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensATTVSTTMAK-FAM (5-carboxyfluorescein-labeled peptide)—0.63—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensAVSTTPAVLK-FAM (5-carboxyfluorescein-labeled peptide)—1.33—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensFAM-AHGVTSAPDTR (5-carboxyfluorescein-labeled peptide)—0.11—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensGPTEVAQTPTPETFLTTIK-FAM (5-carboxyfluorescein-labeled peptide)—0.07—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T13Homo sapiensPTPSATTPAPPSSSAPPETTAAK-FAM (5-carboxyfluorescein-labeled peptide)—0.046—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T9Homo sapiensFAM-AHGVTSAPDTR (5-carboxyfluorescein-labeled peptide)—0.07—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T9Homo sapiensGPTEVAQTPTPETFLTTIK-FAM (5-carboxyfluorescein-labeled peptide)—0.96—pH 7.4, 37 °CPMID 12407114Open
pp-GalNAc-T9Homo sapiensPTPSATTPAPPSSSAPPETTAAK-FAM (5-carboxyfluorescein-labeled peptide)—0.02—pH 7.4, 37 °CPMID 12407114Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-130.40.530.76 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-13catalytic domain of ppGalNAcT-100.310.770.40 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-30.330.0963.4 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-3catalytic domain of ppGalNAcT-100.240.054.8 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-3,131.40.443.2 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-3,13catalytic domain of ppGalNAcT-100.7610.76 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 10)Homo sapiensMUC5AC-9—2.4—pH 6.6PMID 18562306Open
ppGalNAcT-10 catalytic domain / ppGalNAcT-2 lectin domain chimera (hT10CD-hT2LD)chimera hT10CD-hT2LD (hT10 catalytic domain + hT2 lectin domain)Homo sapiensMUC5AC-130.290.640.45 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 catalytic domain / ppGalNAcT-2 lectin domain chimera (hT10CD-hT2LD)chimera hT10CD-hT2LD (hT10 catalytic domain + hT2 lectin domain)Homo sapiensMUC5AC-30.150.1071.4 calc.pH 6.6PMID 18562306Open
ppGalNAcT-10 catalytic domain / ppGalNAcT-2 lectin domain chimera (hT10CD-hT2LD)chimera hT10CD-hT2LD (hT10 catalytic domain + hT2 lectin domain)Homo sapiensMUC5AC-3,130.520.570.91 calc.pH 6.6PMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC peptide0.0520.022.6 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC peptidecatalytic domain of ppGalNAcT-20.050.0182.8 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC peptide0.04——25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC peptidecatalytic domain of ppGalNAcT-20.053——25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-130.1030.0185.7 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-13Thr-9; catalytic domain of ppGalNAcT-20.0670.170.39 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-13glycosylation site Thr-30.108——25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-13glycosylation site Thr-9; catalytic domain of ppGalNAcT-20.075——25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-3glycosylation site Thr-130.2180.0336.6 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-3glycosylation site Thr-9; catalytic domain of ppGalNAcT-20.0580.0361.6 calc.pH 6.6, 25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-3glycosylation site Thr-130.22——25 °CPMID 18562306Open
ppGalNAcT-2 (UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase 2)Homo sapiensMUC5AC-3glycosylation site Thr-9; catalytic domain of ppGalNAcT-20.04——25 °CPMID 18562306Open
tgGalNAc-T3 (zebra finch polypeptide N-acetylgalactosaminyltransferase 3)Taeniopygia guttataGAGADDDYAVTPGPDDDAGAG32.170.77241.7 calc.pH 6.8, 37 °CPMID 37555669Open
tgGalNAc-T3 (zebra finch polypeptide N-acetylgalactosaminyltransferase 3)Taeniopygia guttataGAGAGAGYAVTPGPGAGAGAG44.170.149296 calc.pH 6.8, 37 °CPMID 37555669Open
tgGalNAc-T3 (zebra finch polypeptide N-acetylgalactosaminyltransferase 3)Taeniopygia guttataGAGARRRYAVTPGPRRRAGAG47.670.0585815 calc.pH 6.8, 37 °CPMID 37555669Open