EC 2.4.2.4: thymidine phosphorylase
TransferasesOpen in Browse
CatLog read 13 records for EC 2.4.2.4 from 2 papers, for 1 organism. Names in these papers: thymidine phosphorylase, thymidine phosphorylase (EcTP).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 30 records for EC 2.4.2.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.2.4 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Substrate specificity of Escherichia coli thymidine phosphorylase | Escherichia coli | 11 |
| Efficient whole-cell biocatalytic synthesis of 2'-deoxy-2'-fluoroadenosine, a key building block for nucleic acid drugs | Escherichia coli | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| thymidine phosphorylase | Escherichia coli | 1-(2,5-dideoxy-β-D-erythro-hexofuranosyl)thymine | 0.6 | 0.3 | 2 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 1-(2,5-dideoxy-β-D-erythro-hexofuranosyl)thymine |
| thymidine phosphorylase | Escherichia coli | 1-(2,6-dideoxy-α-L-lyxo-hexofuranosyl)thymine | 0.45 | 0.35 | 1.3 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 1-(2,6-dideoxy-α-L-lyxo-hexofuranosyl)thymine |
| thymidine phosphorylase | Escherichia coli | 1-(2,6-dideoxy-β-D-ribo-hexofuranosyl)thymine | 0.1 | 0.33 | 0.3 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 1-(2,6-dideoxy-β-D-ribo-hexofuranosyl)thymine |
| thymidine phosphorylase | Escherichia coli | 2′,3′-didehydro-2′,3′-dideoxythymidine | 0.4 | 0.35 | 1.1 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 2′,3′-didehydro-2′,3′-dideoxythymidine |
| thymidine phosphorylase | Escherichia coli | 2′-deoxyuridine | 35 | 0.32 | 180 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 2′-deoxyuridine |
| thymidine phosphorylase | Escherichia coli | 3′-amino-3′-deoxythymidine | 1.1 | 0.4 | 2.7 | pH 8, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 3′-amino-3′-deoxythymidine |
| thymidine phosphorylase | Escherichia coli | 4-thiothymidine | 63 | 0.28 | 250 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 4-thiothymidine |
| thymidine phosphorylase | Escherichia coli | 5′-amino-5′-deoxythymidine | 0.58 | 0.4 | 1.5 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 5′-amino-5′-deoxythymidine |
| thymidine phosphorylase | Escherichia coli | 5′-chloro-5′-deoxythymidine | 1.7 | 0.3 | 6 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 5′-chloro-5′-deoxythymidine |
| thymidine phosphorylase | Escherichia coli | 5′-deoxythymidine | 260 | 0.4 | 640 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, 5′-deoxythymidine |
| thymidine phosphorylase | Escherichia coli | thymidine | 198 | 0.3 | 660 | pH 6.5, 25 °C | PMID 17309433 | Open record: thymidine phosphorylase, thymidine |
| thymidine phosphorylase (EcTP) | Escherichia coli | 2'-deoxy-2'-fluorouridinenon-pretreated cells | 0.3085 | 11.1 | 0.0278 | pH 7 | PMID 42179739 | Open record: thymidine phosphorylase (EcTP), 2'-deoxy-2'-fluorouridine |
| thymidine phosphorylase (EcTP) | Escherichia coli | 2'-deoxy-2'-fluorouridinecells thermally pretreated at 50 °C for 3 h | 0.3195 | 9.95 | 0.0322 | pH 7 | PMID 42179739 | Open record: thymidine phosphorylase (EcTP), 2'-deoxy-2'-fluorouridine |