EC 2.6.1.39: 2-aminoadipate transaminase
TransferasesOpen in Browse
CatLog read 53 records for EC 2.6.1.39 from 2 papers, for 2 organisms. Names in these papers: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-aminoadipate aminotransferase (AAA-AT).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 9 records for EC 2.6.1.39 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.6.1.39 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II | Homo sapiens | 28 |
| Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus | Thermus thermophilus | 25 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | 3-hydroxy-kynurenine | 1.702 | 3.8 | 0.447 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), 3-hydroxy-kynurenine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Alanine | 2.893 | 19.4 | 0.15 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Alanine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Aminobutyrate | 2.62 | 17.8 | 0.147 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Aminobutyrate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Glutamate | 3.083 | 1.6 | 1.978 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Glutamate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Glutamine | 1.592 | 8.1 | 0.197 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Glutamine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Glyoxylate | 3.64 | 18 | 0.202 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Glyoxylate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Hydroxyphenylpyruvate | 0.393 | 1.5 | 0.27 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Hydroxyphenylpyruvate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | indole-3-pyruvate | 1.485 | 1.4 | 1.077 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), indole-3-pyruvate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | L-kynurenine | 9.755 | 4.7 | 2.098 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), L-kynurenine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Leucine | 4.75 | 5.1 | 0.935 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Leucine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Mercaptopyruvate | 3.592 | 2.8 | 1.295 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Mercaptopyruvate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Methionine | 3.44 | 1.7 | 2.063 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Methionine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Oxaloacetate | 1.565 | 16.8 | 0.093 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Oxaloacetate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Phenylalanine | 5.452 | 5.2 | 1.057 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Phenylalanine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Phenylpyruvate | 4.733 | 1.8 | 2.615 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Phenylpyruvate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Pyruvate | 0.363 | 9.7 | 0.038 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Pyruvate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Tryptophan | 4.233 | 4.3 | 0.978 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Tryptophan |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | Tyrosine | 2.192 | 1.8 | 1.24 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), Tyrosine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-aminoadipate | 2.99 | 0.9 | 3.27 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-aminoadipate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-oxo-γ-methiol-butyric acid | 4.27 | 2.4 | 1.753 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-oxo-γ-methiol-butyric acid |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxoadipate | 4.838 | 20.9 | 0.232 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxoadipate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxobutyrate | 3.482 | 12.7 | 0.273 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxobutyrate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxocaproic acid | 4.828 | 1.5 | 3.133 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxocaproic acid |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxoglutarate | 7.668 | 1.2 | 6.242 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxoglutarate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxoisoleucine | 0.92 | 14.2 | 0.065 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxoisoleucine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxoleucine | 2.508 | 3.3 | 0.757 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxoleucine |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxovalerate | 2.655 | 3.4 | 0.783 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxovalerate |
| kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT) | Homo sapiens | α-Oxovaline | 0.918 | 12.9 | 0.072 | pH 7.4, 37 °C | PMID 18620547 | Open record: kynurenine aminotransferase II / aminoadipate aminotransferase (hKAT II/AADAT), α-Oxovaline |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | 2-oxoglutaratecosubstrate AAA | — | 0.3 | 22 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | 2-oxoglutaratecosubstrate Leu | — | 0.27 | 19 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | 2-oxoisocaproate | — | 0.43 | 34 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), 2-oxoisocaproate |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | L-aspartate | 0.046 | 381 | 1.2 × 10⁻⁴ calc. | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), L-aspartate |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | L-glutamate | 16 | 0.46 | 37 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), L-glutamate |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | L-leucine | 5.1 | 0.95 | 5.4 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), L-leucine |
| α-aminoadipate aminotransferase (AAA-AT) | Thermus thermophilus | α-aminoadipate | 6.7 | 0.81 | 8.2 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT), α-aminoadipate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | 2-oxoglutaratecosubstrate AAA | — | 0.54 | 0.021 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | 2-oxoglutaratecosubstrate Leu | — | 0.61 | 0.015 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | 2-oxoisocaproate | — | 0.048 | 4.8 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, 2-oxoisocaproate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | L-glutamate | 0.23 | 250 | 9 × 10⁻⁴ | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, L-glutamate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | L-leucine | 0.009 | 0.39 | 0.023 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, L-leucine |
| α-aminoadipate aminotransferase (AAA-AT)variant R23A | Thermus thermophilus | α-aminoadipate | 0.011 | 3.3 | 0.0033 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23A, α-aminoadipate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | 2-oxoglutaratecosubstrate AAA | — | 0.42 | 0.2 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | 2-oxoglutaratecosubstrate Leu | — | 0.55 | 0.091 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | 2-oxoisocaproate | — | 0.091 | 5.5 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, 2-oxoisocaproate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | L-glutamate | 0.5 | 62 | 0.0081 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, L-glutamate |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | L-leucine | 0.05 | 0.88 | 0.057 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, L-leucine |
| α-aminoadipate aminotransferase (AAA-AT)variant R23Q | Thermus thermophilus | α-aminoadipate | 0.083 | 11 | 0.0075 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant R23Q, α-aminoadipate |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | 2-oxoglutaratecosubstrate AAA | — | 0.41 | 0.097 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | 2-oxoglutaratecosubstrate Leu | — | 0.4 | 0.06 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, 2-oxoglutarate |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | 2-oxoisocaproate | — | 0.05 | 24 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, 2-oxoisocaproate |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | L-glutamate | 1.2 | 82 | 0.014 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, L-glutamate |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | L-leucine | 0.023 | 0.2 | 0.12 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, L-leucine |
| α-aminoadipate aminotransferase (AAA-AT)variant S20E | Thermus thermophilus | α-aminoadipate | 0.04 | 7 | 0.0057 | pH 8, 45 °C | PMID 19632206 | Open record: α-aminoadipate aminotransferase (AAA-AT) variant S20E, α-aminoadipate |