EC 2.7.1.169: pantoate kinase
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CatLog read 12 records for EC 2.7.1.169 from 2 papers, for 2 organisms. Names in these papers: pantoate kinase (PoK), pantoate kinase (PoK, TK2141 protein).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biochemical characterization of pantoate kinase, a novel enzyme necessary for coenzyme A biosynthesis in the Archaea | Thermococcus kodakarensis | 10 |
| Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea | Thermococcus kodakaraensis | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| pantoate kinase (PoK) | Thermococcus kodakarensis | (R)-2,4-dihydroxy-3,3-dimethylbutanoate | 2.82 | 2.92 | 0.966 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), (R)-2,4-dihydroxy-3,3-dimethylbutanoate |
| pantoate kinase (PoK) | Thermococcus kodakarensis | adenosine 5'-triphosphateNaCl added to equalize Na+; 5 mM KCl | 0.99 | 0.45 | 2.2 | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), adenosine 5'-triphosphate |
| pantoate kinase (PoK) | Thermococcus kodakarensis | adenosine 5'-triphosphate | 1.48 | 0.32 | 4.6 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), adenosine 5'-triphosphate |
| pantoate kinase (PoK) | Thermococcus kodakarensis | cytidine 5'-triphosphate | 0.47 | 0.34 | 1.4 | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), cytidine 5'-triphosphate |
| pantoate kinase (PoK) | Thermococcus kodakarensis | guanosine 5'-triphosphate | 0.32 | 0.43 | 0.74 | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), guanosine 5'-triphosphate |
| pantoate kinase (PoK) | Thermococcus kodakarensis | uridine 5'-triphosphate | 1.11 | 0.17 | 6.5 | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK), uridine 5'-triphosphate |
| pantoate kinase (PoK)variant H131A | Thermococcus kodakarensis | adenosine 5'-triphosphate | 1.45 | 0.13 | 11 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK) variant H131A, adenosine 5'-triphosphate |
| pantoate kinase (PoK)variant R155A | Thermococcus kodakarensis | adenosine 5'-triphosphate | 0.59 | 2.82 | 0.21 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK) variant R155A, adenosine 5'-triphosphate |
| pantoate kinase (PoK)variant S28A | Thermococcus kodakarensis | adenosine 5'-triphosphate | 1.81 | 0.22 | 8.2 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK) variant S28A, adenosine 5'-triphosphate |
| pantoate kinase (PoK)variant T186A | Thermococcus kodakarensis | adenosine 5'-triphosphate | 0.21 | 0.27 | 0.78 calc. | pH 7.5, 42 °C | PMID 22865846 | Open record: pantoate kinase (PoK) variant T186A, adenosine 5'-triphosphate |
| pantoate kinase (PoK, TK2141 protein) | Thermococcus kodakaraensis | ATP | 1.48 | 0.47 | 3.1 | pH 8, 42 °C | PMID 19666462 | Open record: pantoate kinase (PoK, TK2141 protein), ATP |
| pantoate kinase (PoK, TK2141 protein) | Thermococcus kodakaraensis | D-pantoate | 1.56 | 1.2 | 1.3 | pH 8, 42 °C | PMID 19666462 | Open record: pantoate kinase (PoK, TK2141 protein), D-pantoate |