EC 2.7.1.36: mevalonate kinase
TransferasesOpen in Browse
CatLog read 50 records for EC 2.7.1.36 from 3 papers, for 4 organisms. Names in these papers: mevalonate kinase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 58 records for EC 2.7.1.36 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.36 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Phosphorothioate analogues of adenosine triphosphate as substrates of the mevalonate kinase reaction | Sus scrofa | 22 |
| Effect of a disulfide bond on mevalonate kinase | Methanococcus jannaschii, Rattus norvegicus | 16 |
| Identification of catalytic residues in human mevalonate kinase | Homo sapiens | 12 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| mevalonate kinase | Homo sapiens | adenosine 5'-triphosphate | — | 0.074 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase, adenosine 5'-triphosphate |
| mevalonate kinase | Homo sapiens | DL-mevalonic acid | — | 0.024 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase, DL-mevalonic acid |
| mevalonate kinasevariant D204A | Homo sapiens | adenosine 5'-triphosphate | — | 0.025 | — | PMID 9325256 | Open record: mevalonate kinase variant D204A, adenosine 5'-triphosphate | |
| mevalonate kinasevariant D204A | Homo sapiens | DL-mevalonic acid | — | 0.02 | — | PMID 9325256 | Open record: mevalonate kinase variant D204A, DL-mevalonic acid | |
| mevalonate kinasevariant D204N | Homo sapiens | adenosine 5'-triphosphate | — | 0.066 | — | PMID 9325256 | Open record: mevalonate kinase variant D204N, adenosine 5'-triphosphate | |
| mevalonate kinasevariant D204N | Homo sapiens | DL-mevalonic acid | — | 0.012 | — | PMID 9325256 | Open record: mevalonate kinase variant D204N, DL-mevalonic acid | |
| mevalonate kinasevariant E193Q | Homo sapiens | adenosine 5'-triphosphate | — | 1.56 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E193Q, adenosine 5'-triphosphate |
| mevalonate kinasevariant E193Q | Homo sapiens | DL-mevalonic acid | — | 1.02 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E193Q, DL-mevalonic acid |
| mevalonate kinasevariant E19D | Homo sapiens | adenosine 5'-triphosphate | — | 0.113 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E19D, adenosine 5'-triphosphate |
| mevalonate kinasevariant E19D | Homo sapiens | DL-mevalonic acid | — | 0.052 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E19D, DL-mevalonic acid |
| mevalonate kinasevariant E296Q | Homo sapiens | adenosine 5'-triphosphate | — | 0.131 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E296Q, adenosine 5'-triphosphate |
| mevalonate kinasevariant E296Q | Homo sapiens | DL-mevalonic acid | — | 0.011 | — | pH 7, 30 °C | PMID 9325256 | Open record: mevalonate kinase variant E296Q, DL-mevalonic acid |
| mevalonate kinase | Methanococcus jannaschii | (RS)-mevalonic acid | 28.5 | 0.106 | 269 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase, (RS)-mevalonic acid |
| mevalonate kinase | Methanococcus jannaschii | ATP | — | 1.18 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase, ATP |
| mevalonate kinasevariant C107A | Methanococcus jannaschii | (RS)-mevalonic acid | 17.1 | 0.07 | 240 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107A, (RS)-mevalonic acid |
| mevalonate kinasevariant C107A | Methanococcus jannaschii | ATP | — | 2.61 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107A, ATP |
| mevalonate kinasevariant C107A/C281A | Methanococcus jannaschii | (RS)-mevalonic acid | 8.6 | 0.071 | 120 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107A/C281A, (RS)-mevalonic acid |
| mevalonate kinasevariant C107A/C281A | Methanococcus jannaschii | ATP | — | 1.58 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107A/C281A, ATP |
| mevalonate kinasevariant C107S | Methanococcus jannaschii | (RS)-mevalonic acid | 10.5 | 0.076 | 140 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107S, (RS)-mevalonic acid |
| mevalonate kinasevariant C107S | Methanococcus jannaschii | ATP | — | 3.11 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107S, ATP |
| mevalonate kinasevariant C107S/C281S | Methanococcus jannaschii | (RS)-mevalonic acid | 3.1 | 0.111 | 28 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107S/C281S, (RS)-mevalonic acid |
| mevalonate kinasevariant C107S/C281S | Methanococcus jannaschii | ATP | — | 3.36 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C107S/C281S, ATP |
| mevalonate kinasevariant C281A | Methanococcus jannaschii | (RS)-mevalonic acid | 23.3 | 0.106 | 220 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C281A, (RS)-mevalonic acid |
| mevalonate kinasevariant C281A | Methanococcus jannaschii | ATP | — | 2.76 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C281A, ATP |
| mevalonate kinasevariant C281S | Methanococcus jannaschii | (RS)-mevalonic acid | 12.7 | 0.061 | 210 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C281S, (RS)-mevalonic acid |
| mevalonate kinasevariant C281S | Methanococcus jannaschii | ATP | — | 2.97 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant C281S, ATP |
| mevalonate kinasevariant A141C | Rattus norvegicus | (RS)-mevalonic acid | 5.2 | 0.186 | 28 calc. | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant A141C, (RS)-mevalonic acid |
| mevalonate kinasevariant A141C | Rattus norvegicus | ATP | — | 0.97 | — | pH 7.5, 34 °C | PMID 17964869 | Open record: mevalonate kinase variant A141C, ATP |
| mevalonate kinase | Sus scrofa | Ca2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.596 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Ca2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Ca2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.139 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Ca2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Cd2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer | — | 0.216 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Cd2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Cd2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer | — | 0.282 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Cd2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Cd2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.059 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Cd2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Cd2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.461 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Cd2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Co2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer | — | 0.088 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Co2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Co2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer | — | 0.198 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Co2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Co2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.05 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Co2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Co2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.1 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Co2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer | — | 2.44 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-O-(1-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer | — | 0.164 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-O-(1-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.59 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.121 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-O-(3-thiotriphosphate) | — | 0.57 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-O-(3-thiotriphosphate) |
| mevalonate kinase | Sus scrofa | Mg2+ complex of adenosine 5'-triphosphate | — | 0.69 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mg2+ complex of adenosine 5'-triphosphate |
| mevalonate kinase | Sus scrofa | Mn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.293 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Mn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.075 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Mn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Ni2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.091 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Ni2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Ni2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.139 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Ni2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |
| mevalonate kinase | Sus scrofa | Zn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer | — | 0.12 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Zn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Rp diastereomer |
| mevalonate kinase | Sus scrofa | Zn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer | — | 0.058 | — | pH 8 | PMID 6329303 | Open record: mevalonate kinase, Zn2+ complex of adenosine 5'-O-(2-thiotriphosphate), Sp diastereomer |