CatLogenzyme kinetics catalog

EC 2.7.4.2: phosphomevalonate kinase

TransferasesOpen in Browse

CatLog read 56 records for EC 2.7.4.2 from 2 papers, for 1 organism. Names in these papers: phosphomevalonate kinase (PMK).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 16 records for EC 2.7.4.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.4.2 in Browse.

Papers

PaperOrganismsRecords
Functional evaluation of conserved basic residues in human phosphomevalonate kinaseHomo sapiens36
Phosphomevalonate kinase: functional investigation of the recombinant human enzymeHomo sapiens20

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
phosphomevalonate kinase (PMK)Homo sapiens(R)-mevalonate 5-diphosphate—0.041—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)Homo sapiens(R)-mevalonate 5-phosphate—0.034—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)Homo sapiensMgADP—0.047—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)Homo sapiensMgATP—0.107—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant D23NHomo sapiens(R)-mevalonate 5-diphosphate—0.138—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant D23NHomo sapiens(R)-mevalonate 5-phosphate—0.116—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant D23NHomo sapiensMgADP—0.079—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant D23NHomo sapiensMgATP—0.815—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K17MHomo sapiens(R)-mevalonate 5-diphosphate—0.187—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K17MHomo sapiens(R)-mevalonate 5-phosphate—0.176—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K17MHomo sapiensMgADP—0.286—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K17MHomo sapiensMgATP—0.556—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K19MHomo sapiens(R)-mevalonate 5-diphosphate—0.079—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K19MHomo sapiens(R)-mevalonate 5-phosphate—0.23—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K19MHomo sapiensMgADP—0.131—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K19MHomo sapiensMgATP—1.312—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant K48MHomo sapiens(R)-mevalonate 5-diphosphate—0.007—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K48MHomo sapiens(R)-mevalonate 5-phosphate—0.131—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K48MHomo sapiensADP—0.06—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K48MHomo sapiensATP—0.236—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K69MHomo sapiens(R)-mevalonate 5-diphosphate—0.044—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K69MHomo sapiens(R)-mevalonate 5-phosphate—0.11—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K69MHomo sapiensADP—0.106—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant K69MHomo sapiensATP—0.268—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R111MHomo sapiens(R)-mevalonate 5-diphosphate—1.25—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R111MHomo sapiens(R)-mevalonate 5-phosphate—2.04—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R111MHomo sapiensADP—0.093—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R111MHomo sapiensATP—0.792—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R130MHomo sapiens(R)-mevalonate 5-diphosphate—0.102—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R130MHomo sapiens(R)-mevalonate 5-phosphate—0.102—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R130MHomo sapiensADP—0.164—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R130MHomo sapiensATP—0.229—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R138MHomo sapiens(R)-mevalonate 5-diphosphate—0.057—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R138MHomo sapiens(R)-mevalonate 5-phosphate—0.047—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R138MHomo sapiensADP—0.451—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R138MHomo sapiensATP—0.518—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R141MHomo sapiens(R)-mevalonate 5-diphosphate—0.139—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R141MHomo sapiens(R)-mevalonate 5-phosphate—0.225—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R141MHomo sapiensADP—5.62—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R141MHomo sapiensATP—5.2—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R18QHomo sapiens(R)-mevalonate 5-diphosphate—0.047—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant R18QHomo sapiens(R)-mevalonate 5-phosphate—0.123—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant R18QHomo sapiensMgADP—0.065—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant R18QHomo sapiensMgATP—0.536—pH 7, 30 °CPMID 16519518Open
phosphomevalonate kinase (PMK)variant R73MHomo sapiens(R)-mevalonate 5-diphosphate—0.041—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R73MHomo sapiens(R)-mevalonate 5-phosphate—0.1—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R73MHomo sapiensADP—0.118—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R73MHomo sapiensATP—0.094—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R84MHomo sapiens(R)-mevalonate 5-diphosphate—1.55—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R84MHomo sapiens(R)-mevalonate 5-phosphate—1.71—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R84MHomo sapiensADP—0.238—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R84MHomo sapiensATP—0.303—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R93MHomo sapiens(R)-mevalonate 5-diphosphate—0.045—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R93MHomo sapiens(R)-mevalonate 5-phosphate—0.048—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R93MHomo sapiensADP—0.091—pH 7, 30 °CPMID 17902708Open
phosphomevalonate kinase (PMK)variant R93MHomo sapiensATP—0.101—pH 7, 30 °CPMID 17902708Open