CatLogenzyme kinetics catalog

EC 2.7.6.1: ribose-phosphate diphosphokinase

TransferasesOpen in Browse

CatLog read 20 records for EC 2.7.6.1 from 2 papers, for 2 organisms. Names in these papers: phosphoribosyl diphosphate synthase (PRibPP synthase), phosphoribosylpyrophosphate synthase (MtPRS).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 99 records for EC 2.7.6.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.6.1 in Browse.

Papers

PaperOrganismsRecords
Catalytic residues Lys197 and Arg199 of Bacillus subtilis phosphoribosyl diphosphate synthase. Alanine-scanning mutagenesis of the flexible catalytic loopBacillus subtilis15
Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?Mycobacterium tuberculosis5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
phosphoribosyl diphosphate synthase (PRibPP synthase)Bacillus subtilisATP—0.191—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)Bacillus subtilisD-ribose 5-phosphate—0.23—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant E206ABacillus subtilisATP—0.48—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant K197ABacillus subtilisATP—0.12—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant K197ABacillus subtilisD-ribose 5-phosphate—0.217—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant M208ABacillus subtilisATP—0.23—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant N203ABacillus subtilisATP—0.87—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant P200ABacillus subtilisATP—0.13—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant P202ABacillus subtilisATP—0.29—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant R198ABacillus subtilisATP—0.19—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant R199ABacillus subtilisATP—0.057—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant R199ABacillus subtilisD-ribose 5-phosphate—0.106—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant R201ABacillus subtilisATP—0.56—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant V204ABacillus subtilisATP—0.19—pH 8, 37 °CPMID 16008562Open
phosphoribosyl diphosphate synthase (PRibPP synthase)variant V207ABacillus subtilisATP—0.16—pH 8, 37 °CPMID 16008562Open
phosphoribosylpyrophosphate synthase (MtPRS)Mycobacterium tuberculosisadenosine 5'-triphosphate0.660.02526pH 8, 25 °CPMID 22745722Open
phosphoribosylpyrophosphate synthase (MtPRS)Mycobacterium tuberculosisalpha-D-ribose 5-phosphate0.830.01459pH 8, 25 °CPMID 22745722Open
phosphoribosylpyrophosphate synthase (MtPRS)Mycobacterium tuberculosiscytidine 5'-triphosphate0.0650.0262.5pH 8, 25 °CPMID 22745722Open
phosphoribosylpyrophosphate synthase (MtPRS)Mycobacterium tuberculosisguanosine 5'-triphosphate0.140.0373.8pH 8, 25 °CPMID 22745722Open
phosphoribosylpyrophosphate synthase (MtPRS)Mycobacterium tuberculosisuridine 5'-triphosphate0.1550.0523pH 8, 25 °CPMID 22745722Open