CatLogenzyme kinetics catalog

EC 2.7.6.2: thiamine diphosphokinase

TransferasesOpen in Browse

CatLog read 17 records for EC 2.7.6.2 from 1 paper, for 1 organism. Names in these papers: thiamin pyrophosphokinase (hTPK1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 27 records for EC 2.7.6.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.6.2 in Browse.

Papers

PaperOrganismsRecords
Steady-state kinetics and mutational studies of recombinant human thiamin pyrophosphokinaseHomo sapiens17

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
thiamin pyrophosphokinase (hTPK1)Homo sapiensATP—1.2—pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)Homo sapiensATP——0.059pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)Homo sapiensthiaminTable 30.069—330pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)Homo sapiensthiaminin the text—2.1 × 10⁻⁴—pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant D100NHomo sapiensthiamin2 × 10⁻⁴——pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant D133NHomo sapiensATP—0.650.052pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant D133NHomo sapiensthiamin0.0348.2 × 10⁻⁴41pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant D71NHomo sapiensthiamin5 × 10⁻⁴——pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant D73NHomo sapiensthiamin3 × 10⁻⁴——pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant Q96EHomo sapiensATP—10.044pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant Q96EHomo sapiensthiamin0.0453.9 × 10⁻⁵1.2 × 10³pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant R131GHomo sapiensATP—20.014pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant R131GHomo sapiensthiamin0.0287.6 × 10⁻⁵370pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant S74AHomo sapiensATP—2.40.04pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant S74AHomo sapiensthiamin0.0942.3 × 10⁻⁴410pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant T99AHomo sapiensATP—3.50.0074pH 7.5, 37 °CPMID 12953792Open
thiamin pyrophosphokinase (hTPK1)variant T99AHomo sapiensthiamin0.0261.6 × 10⁻⁴160pH 7.5, 37 °CPMID 12953792Open