EC 2.7.8.7: holo-[acyl-carrier-protein] synthase

TransferasesOpen in Browse

CatLog read 90 records for EC 2.7.8.7 from 6 papers, for 9 organisms. Names in these papers: acyl carrier protein synthase (AcpS), AcpS (acyl carrier protein synthase), Sfp, phosphopantetheinyl transferase and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 31 records for EC 2.7.8.7 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.8.7 in Browse.

Papers

Papers with records for EC 2.7.8.7
PaperOrganismsRecords
Acyl carrier protein synthases from gram-negative, gram-positive, and atypical bacterial species: Biochemical and structural properties and physiological implicationsEscherichia coli, Mycoplasma pneumoniae and 1 more28
Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognitionBacillus subtilis19
Rapid and flexible biochemical assays for evaluating 4'-phosphopantetheinyl transferase activityBacillus subtilis subsp. spizizenii, Pseudomonas aeruginosa and 1 more18
Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferasesBacillus subtilis, Escherichia coli13
Mechanism and substrate recognition of human holo ACP synthaseHomo sapiens10
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5Saccharomyces cerevisiae2

Records

Records for EC 2.7.8.7 read from the paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaperOpen record
AcpSEscherichia colisynthetic 11-residue peptide DSLEFIASKLA0.01350.2420.055PMID 17465518Open record: AcpS, synthetic 11-residue peptide DSLEFIASKLA
AcpSEscherichia colisynthetic 12-residue peptide GDSLDMLEWSLM0.030.1170.25PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLDMLEWSLM
AcpSEscherichia colisynthetic 12-residue peptide GDSLSWLLRCLN9.8 × 10⁻⁴0.1080.0092PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLSWLLRCLN
AcpSEscherichia colisynthetic 12-residue peptide GDSLSWLLRLLN5.5 × 10⁻⁴0.0760.0072PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLSWLLRLLN
AcpSEscherichia colisynthetic 12-residue peptide GDSLSWLLRSLN0.001420.2540.0055PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLSWLLRSLN
AcpSEscherichia colisynthetic 12-residue peptide GDSLSWLVRCLN7 × 10⁻⁴0.07720.009PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLSWLVRCLN
AcpSEscherichia colisynthetic 12-residue peptide GDSLSWLVRLLN5.7 × 10⁻⁴0.1050.0053PMID 17465518Open record: AcpS, synthetic 12-residue peptide GDSLSWLVRLLN
AcpS (acyl carrier protein synthase)Bacillus subtilisACPapo-ACP varied over 2-8 µM0.372 × 10⁻⁴2.15 × 10³pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), ACP
AcpS (acyl carrier protein synthase)Bacillus subtilisACPapo-ACP varied over 20-200 µM2.080.06830pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), ACP
AcpS (acyl carrier protein synthase)Bacillus subtilisPCP-K47A0.0330.0980.33pH 8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), PCP-K47A
AcpS (acyl carrier protein synthase)Bacillus subtilisPCP-K47D0.0830.0851pH 8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), PCP-K47D
AcpS (acyl carrier protein synthase)Bacillus subtilisProCAT-V10.120.07811.537 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), ProCAT-V1
AcpS (acyl carrier protein synthase)Bacillus subtilisProCAT-V30.250.0554.537 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase), ProCAT-V3
AcpS (acyl carrier protein synthase)variant K44ABacillus subtilisACP0.52230.12054.3pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant K44A, ACP
AcpS (acyl carrier protein synthase)variant K44DBacillus subtilisACP0.2090.022669.2pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant K44D, ACP
AcpS (acyl carrier protein synthase)variant R14ABacillus subtilisACP0.3570.0211716.8pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant R14A, ACP
AcpS (acyl carrier protein synthase)variant R14KBacillus subtilisACPapo-ACP varied over 2-34 µM1.6080.00643250pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant R14K, ACP
AcpS (acyl carrier protein synthase)variant R14KBacillus subtilisACPapo-ACP varied over 17.4-173 µM2.5580.0257799.3pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant R14K, ACP
AcpS (acyl carrier protein synthase)variant R14K/K44DBacillus subtilisACP1.4560.0294149.5pH 8.8, 37 °CPMID 15248752Open record: AcpS (acyl carrier protein synthase) variant R14K/K44D, ACP
acyl carrier protein synthase (AcpS)Escherichia coliAcetoacetyl-CoA0.20.008823 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetoacetyl-CoA
acyl carrier protein synthase (AcpS)Escherichia coliAcetyl-CoA0.40.007752 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetyl-CoA
acyl carrier protein synthase (AcpS)Escherichia coliapo-acyl carrier protein (E. coli apo-ACP)0.70.0013540 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), apo-acyl carrier protein (E. coli apo-ACP)
acyl carrier protein synthase (AcpS)Escherichia coliButyryl-CoA0.20.008125 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Butyryl-CoA
acyl carrier protein synthase (AcpS)Escherichia colicoenzyme A10.0093110 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), coenzyme A
acyl carrier protein synthase (AcpS)Escherichia coliMalonyl-CoA0.10.007114 calc.pH 8, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Malonyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeAcetoacetyl-CoA0.0010.0510.020 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetoacetyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeAcetyl-CoA0.0090.0430.21 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeapo-acyl carrier protein (M. pneumoniae apo-ACP)0.0028 × 10⁻⁴2.5 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), apo-acyl carrier protein (M. pneumoniae apo-ACP)
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeButyryl-CoA0.0040.0350.11 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Butyryl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaecoenzyme A0.0020.040.050 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), coenzyme A
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeCrotonyl-CoA0.0050.00520.96 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Crotonyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeDecanoyl-CoA0.0040.00142.9 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Decanoyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeMalonyl-CoA4 × 10⁻⁴0.0940.0043 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Malonyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaeMyristoyl-CoA0.0030.00181.7 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Myristoyl-CoA
acyl carrier protein synthase (AcpS)Mycoplasma pneumoniaePalmitoleoyl-CoA0.0039 × 10⁻⁴3.3 calc.pH 7.2, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Palmitoleoyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeAcetoacetyl-CoA0.20.01911 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetoacetyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeAcetyl-CoA0.20.01118 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Acetyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeapo-acyl carrier protein (S. pneumoniae apo-ACP)0.60.0018330 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), apo-acyl carrier protein (S. pneumoniae apo-ACP)
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeButyryl-CoA0.30.00743 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Butyryl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaecoenzyme A0.30.00475 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), coenzyme A
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeCrotonyl-CoA0.20.01811 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Crotonyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeDecanoyl-CoA0.50.0015330 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Decanoyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeMalonyl-CoA0.10.0156.7 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Malonyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeMyristoleoyl-CoA0.50.0025200 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Myristoleoyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaeMyristoyl-CoA0.50.001500 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Myristoyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaePalmitoleoyl-CoA0.40.0016250 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Palmitoleoyl-CoA
acyl carrier protein synthase (AcpS)Streptococcus pneumoniaePalmitoyl-CoA0.40.0012330 calc.pH 7, 37 °CPMID 16788183Open record: acyl carrier protein synthase (AcpS), Palmitoyl-CoA
Lys5 phosphopantetheinyl transferaseSaccharomyces cerevisiaeapo-peptidyl carrier protein (PCP) domain of Lys2, residues 809-924 (C-terminal His6 fusion)0.050.00150 calc.pH 5.5, 37 °CPMID 10320345Open record: Lys5 phosphopantetheinyl transferase, apo-peptidyl carrier protein (PCP) domain of Lys2, residues 809-924 (C-terminal His6 fusion)
Lys5 phosphopantetheinyl transferaseSaccharomyces cerevisiaecoenzyme A0.050.00150 calc.pH 5.5, 37 °CPMID 10320345Open record: Lys5 phosphopantetheinyl transferase, coenzyme A
PcpSPseudomonas aeruginosaapo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)0.680.0065107pH 8PMID 21466506Open record: PcpS, apo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)
PcpSPseudomonas aeruginosaaryl carrier protein from the Nostoc punctiforme protein HetM——10.8pH 8, 30 °CPMID 21466506Open record: PcpS, aryl carrier protein from the Nostoc punctiforme protein HetM
PcpSPseudomonas aeruginosaBpsA peptidyl carrier protein domain——130pH 8, 30 °CPMID 21466506Open record: PcpS, BpsA peptidyl carrier protein domain
PcpSPseudomonas aeruginosacoenzyme A0.0750.003820pH 7.8PMID 21466506Open record: PcpS, coenzyme A
PcpSPseudomonas aeruginosaPCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD——163pH 8, 30 °CPMID 21466506Open record: PcpS, PCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD
PcpSPseudomonas aeruginosapeptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG——93pH 8, 30 °CPMID 21466506Open record: PcpS, peptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG
phosphopantetheinyl transferaseHomo sapiensacetyl-CoA0.240.02499.63pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase, acetyl-CoA
phosphopantetheinyl transferasevariant D129AHomo sapiensacetyl-CoA9.8 × 10⁻⁵0.1426.7 × 10⁻⁴pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant D129A, acetyl-CoA
phosphopantetheinyl transferasevariant E181AHomo sapiensacetyl-CoA7.2 × 10⁻⁴0.04540.015pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant E181A, acetyl-CoA
phosphopantetheinyl transferasevariant E181QHomo sapiensacetyl-CoA7.3 × 10⁻⁴0.0810.0083pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant E181Q, acetyl-CoA
phosphopantetheinyl transferasevariant E181Q/Q112EHomo sapiensacetyl-CoA4 × 10⁻⁴0.0930.0033pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant E181Q/Q112E, acetyl-CoA
phosphopantetheinyl transferasevariant H111AHomo sapiensacetyl-CoA0.1020.0951.07pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant H111A, acetyl-CoA
phosphopantetheinyl transferasevariant K185AHomo sapiensacetyl-CoA2.5 × 10⁻⁴0.02470.01pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant K185A, acetyl-CoA
phosphopantetheinyl transferasevariant Q112EHomo sapiensacetyl-CoA0.0370.0470.78pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant Q112E, acetyl-CoA
phosphopantetheinyl transferasevariant R47AHomo sapiensacetyl-CoA0.5670.0767.45pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant R47A, acetyl-CoA
phosphopantetheinyl transferasevariant R86AHomo sapiensacetyl-CoA0.9730.3992.43pH 7, 37 °CPMID 18022563Open record: phosphopantetheinyl transferase variant R86A, acetyl-CoA
PP1183Pseudomonas putidaapo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)0.180.008622pH 8PMID 21466506Open record: PP1183, apo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)
PP1183Pseudomonas putidaaryl carrier protein from the Nostoc punctiforme protein HetM——3.2pH 8, 30 °CPMID 21466506Open record: PP1183, aryl carrier protein from the Nostoc punctiforme protein HetM
PP1183Pseudomonas putidaBpsA peptidyl carrier protein domain——65pH 8, 30 °CPMID 21466506Open record: PP1183, BpsA peptidyl carrier protein domain
PP1183Pseudomonas putidacoenzyme A0.0370.0113.3pH 7.8PMID 21466506Open record: PP1183, coenzyme A
PP1183Pseudomonas putidaPCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD——68pH 8, 30 °CPMID 21466506Open record: PP1183, PCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD
PP1183Pseudomonas putidapeptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG——105pH 8, 30 °CPMID 21466506Open record: PP1183, peptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG
SfpBacillus subtilissynthetic 12-residue peptide GDSLDMLEWSLM0.00430.5340.0082PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLDMLEWSLM
SfpBacillus subtilissynthetic 12-residue peptide GDSLSWLLRCLN0.170.121.38PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLSWLLRCLN
SfpBacillus subtilissynthetic 12-residue peptide GDSLSWLLRLLN0.170.05153.2PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLSWLLRLLN
SfpBacillus subtilissynthetic 12-residue peptide GDSLSWLLRSLN0.140.2210.63PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLSWLLRSLN
SfpBacillus subtilissynthetic 12-residue peptide GDSLSWLVRCLN0.0680.1390.48PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLSWLVRCLN
SfpBacillus subtilissynthetic 12-residue peptide GDSLSWLVRLLN0.0520.06180.83PMID 17465518Open record: Sfp, synthetic 12-residue peptide GDSLSWLVRLLN
SfpBacillus subtilis subsp. spizizeniiapo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)0.0350.003310.8pH 8PMID 21466506Open record: Sfp, apo-BpsA (carrier protein substrate; non-ribosomal peptide synthetase BpsA in apo form)
SfpBacillus subtilis subsp. spizizeniiaryl carrier protein from the Nostoc punctiforme protein HetM——58pH 8, 30 °CPMID 21466506Open record: Sfp, aryl carrier protein from the Nostoc punctiforme protein HetM
SfpBacillus subtilis subsp. spizizeniiBpsA peptidyl carrier protein domain——11.5pH 8, 30 °CPMID 21466506Open record: Sfp, BpsA peptidyl carrier protein domain
SfpBacillus subtilis subsp. spizizeniicoenzyme A0.00226.2 × 10⁻⁴3.5pH 7.8PMID 21466506Open record: Sfp, coenzyme A
SfpBacillus subtilis subsp. spizizeniiPCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD——18pH 8, 30 °CPMID 21466506Open record: Sfp, PCP domain of the first module of the Pseudomonas aeruginosa NRPS PvdD
SfpBacillus subtilis subsp. spizizeniipeptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG——55pH 8, 30 °CPMID 21466506Open record: Sfp, peptidyl carrier protein domain of Microcystis aeruginosa non-ribosomal peptide synthetase/polyketide synthetase MycG
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisACPapo-ACP varied over 2-8 µM0.0280.00142037 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), ACP
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisACPapo-ACP varied over 20-200 µM0.2080.038537 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), ACP
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisPCP-K47A1.630.0038430pH 6, 37 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), PCP-K47A
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisPCP-K47D1.530.0058265pH 6, 37 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), PCP-K47D
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisProCAT0.920.0021436.5pH 6, 37 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), ProCAT
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisProCAT-V10.830.0032260.3pH 6, 37 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), ProCAT-V1
Sfp (4'-phosphopantetheinyl transferase)Bacillus subtilisProCAT-V30.80.0065123pH 6, 37 °CPMID 15248752Open record: Sfp (4'-phosphopantetheinyl transferase), ProCAT-V3