EC 2.8.1.2: 3-mercaptopyruvate sulfurtransferase
TransferasesOpen in Browse
CatLog read 52 records for EC 2.8.1.2 from 6 papers, for 4 organisms. Names in these papers: 3-mercaptopyruvate sulfurtransferase (MST), mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate sulfurtransferase (Ec3-MST), TUM1-Iso1 and 3 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 27 records for EC 2.8.1.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.8.1.2 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase | Homo sapiens | 14 |
| doi:10.1021/acscatal.7b02432 | Escherichia coli, Homo sapiens | 14 |
| Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. CDNA cloning, overexpression, and site-directed mutagenesis | Rattus norvegicus | 12 |
| Characterization and interaction studies of two isoforms of the dual localized 3-mercaptopyruvate sulfurtransferase TUM1 from humans | Homo sapiens | 8 |
| Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana | Arabidopsis thaliana | 2 |
| Cytosolic mercaptopyruvate sulfurtransferase is evolutionarily related to mitochondrial rhodanese. Striking similarity in active site amino acid sequence and the increase in the mercaptopyruvate… | Rattus norvegicus | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST) | Escherichia coli | 3-mercaptopyruvate | 112 | 1 | 110 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant D53A | Escherichia coli | 3-mercaptopyruvate | 1 | 2.4 | 0.42 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant D53A, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant H66A | Escherichia coli | 3-mercaptopyruvate | 20 | 0.43 | 47 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant H66A, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant H66A/R102L | Escherichia coli | 3-mercaptopyruvate | 3.9 | 1 | 3.9 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant H66A/R102L, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant H66N | Escherichia coli | 3-mercaptopyruvate | 75 | 1.4 | 54 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant H66N, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant R102K | Escherichia coli | 3-mercaptopyruvate | 59 | 1 | 59 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant R102K, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant R102L | Escherichia coli | 3-mercaptopyruvate | 49 | 0.9 | 54 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant R102L, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant R178L | Escherichia coli | 3-mercaptopyruvate | 0.05 | 15 | 0.0033 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant R178L, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant R178L/R187L | Escherichia coli | 3-mercaptopyruvate | 0.068 | — | — | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant R178L/R187L, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant R187L | Escherichia coli | 3-mercaptopyruvate | 0.16 | 4 | 0.040 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant R187L, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (Ec3-MST)variant S239A | Escherichia coli | 3-mercaptopyruvate | 2.5 | — | — | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (Ec3-MST) variant S239A, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (h3-MST) | Homo sapiens | 3-mercaptopyruvate | 0.47 | — | — | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (h3-MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (h3-MST)variant H66A | Homo sapiens | 3-mercaptopyruvate | 0.48 | 0.79 | 0.61 calc. | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (h3-MST) variant H66A, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (h3-MST)variant S239A | Homo sapiens | 3-mercaptopyruvate | 0.11 | — | — | pH 8, 30 °C | doi:10.1021/acscatal.7b02432 | Open record: 3-mercaptopyruvate sulfurtransferase (h3-MST) variant S239A, 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 2-mercaptoethanol | 229 | — | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 2-mercaptoethanol |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvate0.4 mM lead nitrate; cosubstrate DTT | — | 0.026 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvate25 mM KCN; cosubstrate potassium cyanide | — | 0.35 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvate0.4 mM lead nitrate; cosubstrate Dihydrolipoic acid | — | 0.025 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvateNADPH oxidation at 340 nm; 200 mM HEPES; 20 µM thioredoxin | — | 0.35 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvate0.4 mM lead nitrate; cosubstrate 2-Mercaptoethanol | — | 0.13 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | 3-mercaptopyruvate0.4 mM lead nitrate; cosubstrate Glutathione | — | 0.02 | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | dihydrolipoic acid | 1.7 | 4.4 | 0.39 | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), dihydrolipoic acid |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | dithiothreitol | 6.1 | 4.6 | 1.3 | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), dithiothreitol |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | glutathione (reduced, GSH) | 0.3 | — | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), glutathione (reduced, GSH) |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | human thioredoxin (cytoplasmic) | 1.3 | 0.0025 | 520 | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), human thioredoxin (cytoplasmic) |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | L-cysteine | 1.1 | — | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), L-cysteine |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | L-homocysteine | 0.8 | — | — | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), L-homocysteine |
| 3-mercaptopyruvate sulfurtransferase (MST) | Homo sapiens | potassium cyanide | 2.4 | 6 | 0.4 | pH 7.4, 37 °C | PMID 23698001 | Open record: 3-mercaptopyruvate sulfurtransferase (MST), potassium cyanide |
| mercaptopyruvate sulfurtransferase (MST) | Rattus norvegicus | 3-mercaptopyruvate | 3.8 × 10³ | 1.2 | 3.2 × 10³ | pH 9.55 | PMID 7608189 | Open record: mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate |
| mercaptopyruvate sulfurtransferase (MST) | Rattus norvegicus | 3-mercaptopyruvate | 6.7 × 10³ | 1.2 | 4 × 10³ | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST), 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST) | Rattus norvegicus | thiosulfate | 9 | 73 | 0.125 | pH 5, 25 °C | PMID 7608189 | Open record: mercaptopyruvate sulfurtransferase (MST), thiosulfate |
| mercaptopyruvate sulfurtransferase (MST) | Rattus norvegicus | thiosulfate | 9.3 | 62 | 0.15 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST), thiosulfate | |
| mercaptopyruvate sulfurtransferase (MST)variant G248R | Rattus norvegicus | 3-mercaptopyruvate | 5.5 | 2.1 | 2.7 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant G248R, 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST)variant G248R | Rattus norvegicus | thiosulfate | 0.55 | 14 | 0.04 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant G248R, thiosulfate | |
| mercaptopyruvate sulfurtransferase (MST)variant R187G | Rattus norvegicus | 3-mercaptopyruvate | 7.7 | 70 | 0.11 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant R187G, 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST)variant R187G | Rattus norvegicus | thiosulfate | 1.8 | 340 | 0.0053 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant R187G, thiosulfate | |
| mercaptopyruvate sulfurtransferase (MST)variant R196G | Rattus norvegicus | 3-mercaptopyruvate | 1.7 × 10³ | 11 | 152 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant R196G, 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST)variant R196G | Rattus norvegicus | thiosulfate | 30 | 64 | 0.47 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant R196G, thiosulfate | |
| mercaptopyruvate sulfurtransferase (MST)variant S249A | Rattus norvegicus | 3-mercaptopyruvate | 550 | 0.49 | 1.12 × 10³ | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant S249A, 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST)variant S249A | Rattus norvegicus | thiosulfate | 4 | 55 | 0.073 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant S249A, thiosulfate | |
| mercaptopyruvate sulfurtransferase (MST)variant S249K | Rattus norvegicus | 3-mercaptopyruvate | 420 | 1.1 | 400 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant S249K, 3-mercaptopyruvate | |
| mercaptopyruvate sulfurtransferase (MST)variant S249K | Rattus norvegicus | thiosulfate | 6.8 | 4.7 | 1.48 | PMID 8910318 | Open record: mercaptopyruvate sulfurtransferase (MST) variant S249K, thiosulfate | |
| sulfurtransferase ST1 | Arabidopsis thaliana | 3-mercaptopyruvate | 54 | 3.7 | 14.6 | pH 9 | PMID 12482606 | Open record: sulfurtransferase ST1, 3-mercaptopyruvate |
| sulfurtransferase ST1 | Arabidopsis thaliana | thiosulfate | 2.8 | 0.7 | 4.3 | pH 9 | PMID 12482606 | Open record: sulfurtransferase ST1, thiosulfate |
| TUM1-Iso1 | Homo sapiens | 3-mercaptopyruvate3-mercaptopyruvate:dithiothreitol sulfurtransferase activity | 20.87 | 0.55 | 38.15 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso1, 3-mercaptopyruvate |
| TUM1-Iso1 | Homo sapiens | 3-mercaptopyruvate3-mercaptopyruvate:cyanide sulfurtransferase activity | 8.8 | 1.33 | 6.63 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso1, 3-mercaptopyruvate |
| TUM1-Iso1 | Homo sapiens | dithiothreitol | — | 2.69 | 7.77 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso1, dithiothreitol |
| TUM1-Iso1 | Homo sapiens | potassium cyanide | — | 4.45 | 1.97 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso1, potassium cyanide |
| TUM1-Iso2 | Homo sapiens | 3-mercaptopyruvate3-mercaptopyruvate:dithiothreitol sulfurtransferase activity | 20.18 | 0.54 | 38.18 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso2, 3-mercaptopyruvate |
| TUM1-Iso2 | Homo sapiens | 3-mercaptopyruvate3-mercaptopyruvate:cyanide sulfurtransferase activity | 8.62 | 1.29 | 6.7 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso2, 3-mercaptopyruvate |
| TUM1-Iso2 | Homo sapiens | dithiothreitol | — | 2.59 | 7.7 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso2, dithiothreitol |
| TUM1-Iso2 | Homo sapiens | potassium cyanide | — | 4.5 | 1.92 | pH 10.5, 37 °C | PMID 25336638 | Open record: TUM1-Iso2, potassium cyanide |