EC 3.1.2.6: hydroxyacylglutathione hydrolase

HydrolasesOpen in Browse

CatLog read 60 records for EC 3.1.2.6 from 7 papers, for 6 organisms. Names in these papers: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2, glyoxalase II cytosolic form α, glyoxalase II cytosolic form β, glyoxalase II, mitochondrial and 9 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 105 records for EC 3.1.2.6 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.2.6 in Browse.

Papers

Papers with records for EC 3.1.2.6
Paper	Organisms	Records
Demonstration of glyoxalase II in rat liver mitochondria. Partial purification and occurrence in multiple forms	Rattus norvegicus	21
Specific interaction of cytosolic and mitochondrial glyoxalase II with acidic phospholipids in form of liposomes results in the inhibition of the cytosolic enzyme only	Bos taurus, Homo sapiens	10
Isolation of glyoxalase II from two different compartments of rat liver mitochondria. Kinetic and immunochemical characterization of the enzymes	Rattus norvegicus	8
Arabidopsis glyoxalase II contains a zinc/iron binuclear metal center that is essential for substrate binding and catalysis	Arabidopsis thaliana	7
Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts	Homo sapiens, Plasmodium falciparum	6
Biochemical and structural characterization of Salmonella typhimurium glyoxalase II: new insights into metal ion selectivity	Salmonella typhimurium	4
Purification and characterisation of glyoxalase II from human red blood cells	Homo sapiens	4

Records

Records for EC 3.1.2.6 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
cGloII (cytosolic glyoxalase II)	Plasmodium falciparum	S-D-lactoylglutathione	119.6	0.1	1.19 × 10³	pH 7.2, 25 °C	PMID 15843146	Open record: cGloII (cytosolic glyoxalase II), S-D-lactoylglutathione
cGloII (cytosolic glyoxalase II)	Plasmodium falciparum	S-D-lactoylglutathione	—	0.19	—	37 °C	PMID 15843146	Open record: cGloII (cytosolic glyoxalase II), S-D-lactoylglutathione
cGloII (cytosolic glyoxalase II)variant Y185F	Plasmodium falciparum	S-D-lactoylglutathione	—	0.463	—	37 °C	PMID 15843146	Open record: cGloII (cytosolic glyoxalase II) variant Y185F, S-D-lactoylglutathione
cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-lactoylglutathioneno liposomes (control)	—	0.201	—	pH 7.2, 25 °C	PMID 10944391	Open record: cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-lactoylglutathionewith DOPA (dioleoyl phosphatidic acid) liposomes (SUV)	—	0.152	—	pH 7.2, 25 °C	PMID 10944391	Open record: cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-lactoylglutathionewith DPPS (dipalmitoyl phosphatidylserine) liposomes (SUV)	—	0.191	—	pH 7.2, 25 °C	PMID 10944391	Open record: cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-lactoylglutathionewith BBPS (bovine brain phosphatidylserine) liposomes (SUV)	—	0.204	—	pH 7.2, 25 °C	PMID 10944391	Open record: cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-lactoylglutathionewith CL (cardiolipin) liposomes (SUV); 4.8 µM phospholipid	—	0.169	—	pH 7.2, 25 °C	PMID 10944391	Open record: cytosolic glyoxalase II (C-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
GloB (glyoxalase II, hydroxyacylglutathione hydrolase)	Salmonella typhimurium	S-D-lactoylglutathioneenzyme from LB (rich) medium	168.8	0.408	350	pH 7.2, 30 °C	PMID 17764159	Open record: GloB (glyoxalase II, hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
GloB (glyoxalase II, hydroxyacylglutathione hydrolase)	Salmonella typhimurium	S-D-lactoylglutathione20 µM Zn added to the assay	209.9	0.295	710	pH 7.2, 30 °C	PMID 17764159	Open record: GloB (glyoxalase II, hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
GloB (glyoxalase II, hydroxyacylglutathione hydrolase)	Salmonella typhimurium	S-D-lactoylglutathione20 µM iron added to the assay	149.9	0.463	320	pH 7.2, 30 °C	PMID 17764159	Open record: GloB (glyoxalase II, hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
GloB (glyoxalase II, hydroxyacylglutathione hydrolase)	Salmonella typhimurium	S-D-lactoylglutathione20 µM Mn added to the assay	394.9	0.241	1.64 × 10³	pH 7.2, 30 °C	PMID 17764159	Open record: GloB (glyoxalase II, hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-Lactoylglutathione	727	0.146	5 × 10³	pH 7.4, 37 °C	PMID 8504817	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), S-D-Lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase)	Homo sapiens	S-D-Mandelylglutathione	183	0.0218	8.4 × 10³	pH 7.4, 37 °C	PMID 8504817	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), S-D-Mandelylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase)	Homo sapiens	S-Glycolylglutathione	1736	0.237	7.3 × 10³	pH 7.4, 37 °C	PMID 8504817	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), S-Glycolylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase)	Homo sapiens	S-L-Glyceroylglutathione	1486	0.0966	1.5 × 10⁴	pH 7.4, 37 °C	PMID 8504817	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), S-L-Glyceroylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2	Arabidopsis thaliana	S-D-lactoylglutathione	3.93 × 10³	0.063	6.2 × 10⁴ calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant C140A	Arabidopsis thaliana	S-D-lactoylglutathione	6.78 × 10³	0.062	1.1 × 10⁵ calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant C140A, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant D58C	Arabidopsis thaliana	S-D-lactoylglutathione	10.6	0.076	140 calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant D58C, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant H54N	Arabidopsis thaliana	S-D-lactoylglutathione	10.9	0.13	84 calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant H54N, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant K142A	Arabidopsis thaliana	S-D-lactoylglutathione	1.76 × 10³	0.17	1.0 × 10⁴ calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant K142A, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant N178A	Arabidopsis thaliana	S-D-lactoylglutathione	1.19 × 10³	0.098	1.2 × 10⁴ calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant N178A, S-D-lactoylglutathione
glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2variant R225A	Arabidopsis thaliana	S-D-lactoylglutathione	600	0.06	1.0 × 10⁴ calc.		PMID 11085979	Open record: glyoxalase II (hydroxyacylglutathione hydrolase), cytoplasmic GLX2-2 variant R225A, S-D-lactoylglutathione
glyoxalase II (mitochondrial intermembrane space enzyme)	Rattus norvegicus	S-acetoacetylglutathione	—	0.413	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial intermembrane space enzyme), S-acetoacetylglutathione
glyoxalase II (mitochondrial intermembrane space enzyme)	Rattus norvegicus	S-acetylglutathione	—	0.603	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial intermembrane space enzyme), S-acetylglutathione
glyoxalase II (mitochondrial intermembrane space enzyme)	Rattus norvegicus	S-propionylglutathione	—	0.792	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial intermembrane space enzyme), S-propionylglutathione
glyoxalase II (mitochondrial intermembrane space enzyme)	Rattus norvegicus	S-succinylglutathione	—	0.186	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial intermembrane space enzyme), S-succinylglutathione
glyoxalase II (mitochondrial matrix enzyme)	Rattus norvegicus	S-acetoacetylglutathione	—	0.634	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial matrix enzyme), S-acetoacetylglutathione
glyoxalase II (mitochondrial matrix enzyme)	Rattus norvegicus	S-acetylglutathione	—	0.6	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial matrix enzyme), S-acetylglutathione
glyoxalase II (mitochondrial matrix enzyme)	Rattus norvegicus	S-propionylglutathione	—	1.2	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial matrix enzyme), S-propionylglutathione
glyoxalase II (mitochondrial matrix enzyme)	Rattus norvegicus	S-succinylglutathione	—	0.535	—	20 °C	PMID 2804125	Open record: glyoxalase II (mitochondrial matrix enzyme), S-succinylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-(β-ethoxy-α-D-hydroxybutyryl)glutathione	—	0.044	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-(β-ethoxy-α-D-hydroxybutyryl)glutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-acetoacetylglutathione	—	0.841	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-acetoacetylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-acetylglutathione	—	0.568	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-acetylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-D-lactoylglutathione	—	0.433	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-D-lactoylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-formylglutathione	—	0.213	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-formylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-propionylglutathione	—	0.214	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-propionylglutathione
glyoxalase II cytosolic form α	Rattus norvegicus	S-succinylglutathione	—	0.325	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form α, S-succinylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-(β-ethoxy-α-D-hydroxybutyryl)glutathione	—	0.048	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-(β-ethoxy-α-D-hydroxybutyryl)glutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-acetoacetylglutathione	—	0.376	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-acetoacetylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-acetylglutathione	—	0.662	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-acetylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-D-lactoylglutathione	—	0.464	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-D-lactoylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-formylglutathione	—	0.22	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-formylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-propionylglutathione	—	0.225	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-propionylglutathione
glyoxalase II cytosolic form β	Rattus norvegicus	S-succinylglutathione	—	0.373	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II cytosolic form β, S-succinylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-(β-ethoxy-α-D-hydroxybutyryl)glutathione	—	0.05	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-(β-ethoxy-α-D-hydroxybutyryl)glutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-acetoacetylglutathione	—	0.703	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-acetoacetylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-acetylglutathione	—	0.662	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-acetylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-D-lactoylglutathione	—	0.44	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-D-lactoylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-formylglutathione	—	0.242	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-formylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-propionylglutathione	—	0.378	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-propionylglutathione
glyoxalase II, mitochondrial	Rattus norvegicus	S-succinylglutathione	—	0.16	—	pH 7.2, 20 °C	PMID 3382669	Open record: glyoxalase II, mitochondrial, S-succinylglutathione
human glyoxalase II (Human GloII)	Homo sapiens	S-D-lactoylglutathione	46.37	0.248	190	pH 7.2, 25 °C	PMID 15843146	Open record: human glyoxalase II (Human GloII), S-D-lactoylglutathione
human glyoxalase II (Human GloII)	Homo sapiens	S-D-lactoylglutathione	—	0.208	—	37 °C	PMID 15843146	Open record: human glyoxalase II (Human GloII), S-D-lactoylglutathione
mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase)	Bos taurus	S-D-lactoylglutathioneno liposomes (control)	—	0.152	—	pH 7.2, 25 °C	PMID 10944391	Open record: mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase)	Bos taurus	S-D-lactoylglutathionewith DOPA (dioleoyl phosphatidic acid) liposomes (SUV)	—	0.162	—	pH 7.2, 25 °C	PMID 10944391	Open record: mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase)	Bos taurus	S-D-lactoylglutathionewith DPPS (dipalmitoyl phosphatidylserine) liposomes (SUV)	—	0.283	—	pH 7.2, 25 °C	PMID 10944391	Open record: mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase)	Bos taurus	S-D-lactoylglutathionewith BBPS (bovine brain phosphatidylserine) liposomes (SUV)	—	0.255	—	pH 7.2, 25 °C	PMID 10944391	Open record: mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase)	Bos taurus	S-D-lactoylglutathionewith CL (cardiolipin) liposomes (SUV); 4.8 µM phospholipid	—	0.191	—	pH 7.2, 25 °C	PMID 10944391	Open record: mitochondrial glyoxalase II (M-GII; hydroxyacylglutathione hydrolase), S-D-lactoylglutathione
tGloII (targeted glyoxalase II)	Plasmodium falciparum	S-D-lactoylglutathione	64.3	0.225	290	pH 7.2, 25 °C	PMID 15843146	Open record: tGloII (targeted glyoxalase II), S-D-lactoylglutathione