CatLogenzyme kinetics catalog

EC 3.1.3.25: inositol-phosphate phosphatase

HydrolasesOpen in Browse

CatLog read 57 records for EC 3.1.3.25 from 5 papers, for 5 organisms. Names in these papers: myo-inositol monophosphatase, SuhB inositol monophosphatase (IMPase), inositol monophosphatase (IMPase/FBPase), inositol monophosphatase SuhB (IMPase) and 6 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 47 records for EC 3.1.3.25 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.3.25 in Browse.

Papers

PaperOrganismsRecords
The contribution of lysine-36 to catalysis by human myo-inositol monophosphataseHomo sapiens16
Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPaseArchaeoglobus fulgidus, Escherichia coli12
The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coliEscherichia coli12
MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphataseArchaeoglobus fulgidus, Escherichia coli and 2 more9
NADP(H) phosphatase activities of archaeal inositol monophosphatase and eubacterial 3'-phosphoadenosine 5'-phosphate phosphataseArchaeoglobus fulgidus, Methanococcus jannaschii8

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
AF2372 inositol monophosphatase/fructose-1,6-bisphosphataseArchaeoglobus fulgidusD-fructose 1,6-bisphosphate2.7——85 °CPMID 11062561Open
AF2372 inositol monophosphatase/fructose-1,6-bisphosphataseArchaeoglobus fulgidusDL-myo-inositol 1-phosphate2.50.1123 calc.85 °CPMID 11062561Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidus1-deoxy-D-myo-inositol 3-phosphate3.22.31.4 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidus3,5-dideoxy-D-myo-inositol 1-phosphate2.50.1616 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidus3,5-dideoxy-L-myo-inositol 1-phosphate5.84.91.2 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidus3-deoxy-D-myo-inositol 1-phosphate3.90.2317 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidusD-myo-inositol 1-phosphate3.30.1130 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase (IMPase/FBPase)Archaeoglobus fulgidusD-myo-inositol 3-phosphate3.61.72.1 calc.pH 8, 85 °CPMID 15563150Open
inositol monophosphatase AF2372 (archaeal IMPase/FBPase homologue)Archaeoglobus fulgidusD-myo-inositol monophosphate28.70.18160pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase AF2372 (archaeal IMPase/FBPase homologue)Archaeoglobus fulgidusfructose-1,6-bisphosphate23.80.09259pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase AF2372 (archaeal IMPase/FBPase homologue)Archaeoglobus fulgidusNADP+26.30.14188pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase AF2372 (archaeal IMPase/FBPase homologue)Archaeoglobus fulgidusNADPH40.30.36113pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase MJ0109 (archaeal IMPase/FBPase homologue)Methanococcus jannaschiiD-myo-inositol monophosphate4.11.024pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase MJ0109 (archaeal IMPase/FBPase homologue)Methanococcus jannaschiifructose-1,6-bisphosphate8.40.7311.6pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase MJ0109 (archaeal IMPase/FBPase homologue)Methanococcus jannaschiiNADP+50.549.2pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase MJ0109 (archaeal IMPase/FBPase homologue)Methanococcus jannaschiiNADPH6.90.778.9pH 8.5, 85 °CPMID 17616624Open
inositol monophosphatase SuhB (IMPase)Escherichia coli1-deoxy-D-myo-inositol 3-phosphate5.60.228 calc.pH 8, 37 °CPMID 15563150Open
inositol monophosphatase SuhB (IMPase)Escherichia coli3,5-dideoxy-D-myo-inositol 1-phosphate40.05178 calc.pH 8, 37 °CPMID 15563150Open
inositol monophosphatase SuhB (IMPase)Escherichia coli3,5-dideoxy-L-myo-inositol 1-phosphate4.40.144 calc.pH 8, 37 °CPMID 15563150Open
inositol monophosphatase SuhB (IMPase)Escherichia coli3-deoxy-D-myo-inositol 1-phosphate4.40.04794 calc.pH 8, 37 °CPMID 15563150Open
inositol monophosphatase SuhB (IMPase)Escherichia coliD-myo-inositol 1-phosphate4.40.06865 calc.pH 8, 37 °CPMID 15563150Open
inositol monophosphatase SuhB (IMPase)Escherichia coliD-myo-inositol 3-phosphate1.40.06123 calc.pH 8, 37 °CPMID 15563150Open
MJ0109 inositol monophosphatase/fructose-1,6-bisphosphataseMethanococcus jannaschiiD-fructose 1,6-bisphosphate70.038180 calc.85 °CPMID 11062561Open
MJ0109 inositol monophosphatase/fructose-1,6-bisphosphataseMethanococcus jannaschiiD-fructose 1,6-bisphosphate2.7——50 °CPMID 11062561Open
MJ0109 inositol monophosphatase/fructose-1,6-bisphosphataseMethanococcus jannaschiiDL-myo-inositol 1-phosphate4.20.09146 calc.85 °CPMID 11062561Open
MJ0109 inositol monophosphatase/fructose-1,6-bisphosphataseMethanococcus jannaschiiDL-myo-inositol 1-phosphate1.5——50 °CPMID 11062561Open
myo-inositol monophosphataseHomo sapiens4-nitrophenyl phosphate0.6——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphataseHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied over a wide range at 0.5 mM Ins(1)P22——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphataseHomo sapiensD,L-myo-inositol 1-phosphateIns(1)P varied at 0.5 mM Mg2+ (Table 2 footnote b)—0.07—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphataseHomo sapiensD,L-myo-inositol 1-phosphate0.5 mM Mg2+; Ca2+ inhibition series; UNCOMP fit (Figure 5A)—0.09—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphataseHomo sapiensD,L-myo-inositol 1-phosphate0.5 mM Mg2+; Li+ inhibition series; UNCOMP fit (Figure 5C)—0.095—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphataseHomo sapiensD-glucose 6-phosphate1.6——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiens4-nitrophenyl phosphate0.6——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied over a wide range at 0.5 mM Ins(1)P; Table 20.3——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateIns(1)P varied at 1 mM Mg2+ (Table 2 footnote b); Table 2—0.02—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied at fixed Ins(1)P levels; Table 30.25——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied at fixed Ins(1)P levels; expt 2 (Figure 4 inset)0.29——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied at fixed Ins(1)P levels; Table 30.25——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphateMg2+ varied at fixed Ins(1)P levels; expt 2 (Figure 4 inset)0.27——pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphate1 mM Mg2+; Ca2+ inhibition series; UNCOMP fit (Figure 5B)—0.029—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD,L-myo-inositol 1-phosphate1 mM Mg2+; Li+ inhibition series; NONCOMP fit (Figure 5D)—0.024—pH 7.5, 37 °CPMID 8718889Open
myo-inositol monophosphatasevariant K36QHomo sapiensD-glucose 6-phosphate0.2——pH 7.5, 37 °CPMID 8718889Open
SuhB inositol monophosphataseEscherichia coliDL-myo-inositol 1-phosphate6.50.0793 calc.37 °CPMID 11062561Open
SuhB inositol monophosphatase (IMPase)Escherichia coliD-inositol 1-phosphate0.490.114.5 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant G173VEscherichia coliD-inositol 1-phosphate0.295——pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant H98FEscherichia coliD-inositol 1-phosphate0.5040.173.0 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant K251AEscherichia coliD-inositol 1-phosphate0.165——pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R121AEscherichia coliD-inositol 1-phosphate0.3690.132.8 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R183AEscherichia coliD-inositol 1-phosphate0.7470.164.7 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R184AEscherichia coliD-inositol 1-phosphate1.1830.294.1 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R184IEscherichia coliD-inositol 1-phosphate0.357——pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R184I/L96FEscherichia coliD-inositol 1-phosphate0.324——pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R199AEscherichia coliD-inositol 1-phosphate0.199——pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant R248AEscherichia coliD-inositol 1-phosphate0.2670.132.1 calc.pH 8, 37 °CPMID 17652087Open
SuhB inositol monophosphatase (IMPase)variant V249AEscherichia coliD-inositol 1-phosphate0.1750.062.9 calc.pH 8, 37 °CPMID 17652087Open
TM1415 inositol monophosphataseThermotoga maritimaD-fructose 1,6-bisphosphate268——95 °CPMID 11062561Open
TM1415 inositol monophosphataseThermotoga maritimaDL-myo-inositol 1-phosphate2070.131.6 × 10³ calc.95 °CPMID 11062561Open