EC 3.1.3.99: IMP-specific 5'-nucleotidase
HydrolasesOpen in Browse
CatLog read 26 records for EC 3.1.3.99 from 2 papers, for 2 organisms. Names in these papers: IMP-specific 5'-nucleotidase 1 (PfISN1), ecto-5'-nucleotidase CD73 (soluble form sCD73).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 5 records for EC 3.1.3.99 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.3.99 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase | Plasmodium falciparum | 18 |
| Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity | Homo sapiens | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | 2'-deoxyadenosine 5'-monophosphate | 174 | 0.114 | 1.5 × 10³ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), 2'-deoxyadenosine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | adenosine 5'-monophosphate | 187 | 0.0038 | 4.88 × 10⁴ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), adenosine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | beta-nicotinamide mononucleotide | 102 | 0.88 | 120 | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), beta-nicotinamide mononucleotide |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | cytidine 5'-monophosphate | 202 | 0.0564 | 3.6 × 10³ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), cytidine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | guanosine 5'-monophosphate | 132 | 0.0065 | 2.03 × 10⁴ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), guanosine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | inosine 5'-monophosphate | 104 | 0.0071 | 1.47 × 10⁴ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), inosine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | thymidine 5'-monophosphate | 40 | 0.008 | 5 × 10³ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), thymidine 5'-monophosphate |
| ecto-5'-nucleotidase CD73 (soluble form sCD73) | Homo sapiens | uridine 5'-monophosphate | 289 | 0.0316 | 9.1 × 10³ | 37 °C | PMID 22997138 | Open record: ecto-5'-nucleotidase CD73 (soluble form sCD73), uridine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | adenosine 5'-monophosphate | 23.2 | 105.5 | 0.22 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), adenosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | adenosine 5'-monophosphate | 12.5 | — | — | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), adenosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | adenosine 5'-monophosphatewith 4 mM ATP (allosteric activator) | 19.4 | — | — | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), adenosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | inosine 5'-monophosphate | 10.3 | 0.34 | 29.8 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | inosine 5'-monophosphate | 13.5 | 66 | 0.21 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | inosine 5'-monophosphatewith 4 mM ATP (allosteric activator) | 21 | 6.8 | 3.1 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | p-nitrophenyl phosphate | 0.0026 | — | — | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), p-nitrophenyl phosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1) | Plasmodium falciparum | p-nitrophenyl phosphatewith 4 mM ATP (allosteric activator) | 0.0037 | — | — | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1), p-nitrophenyl phosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant D172A | Plasmodium falciparum | p-nitrophenyl phosphate | 0.019 | 4.8 | 0.0039 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant D172A, p-nitrophenyl phosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant D172N | Plasmodium falciparum | p-nitrophenyl phosphate | 0.28 | 1.51 | 0.19 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant D172N, p-nitrophenyl phosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant H398V | Plasmodium falciparum | inosine 5'-monophosphate | 32.5 | 1.6 | 20.3 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant H398V, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant H398V | Plasmodium falciparum | inosine 5'-monophosphate | 16.5 | 10.9 | 1.5 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant H398V, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant K41L | Plasmodium falciparum | inosine 5'-monophosphate | 22.5 | 3.2 | 7 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant K41L, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant K41L | Plasmodium falciparum | inosine 5'-monophosphate | 14.5 | 15.6 | 0.93 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant K41L, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant ΔC10 | Plasmodium falciparum | inosine 5'-monophosphate | 55.1 | 1.6 | 34.4 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant ΔC10, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant ΔC10 | Plasmodium falciparum | inosine 5'-monophosphate | 35.5 | 20.7 | 1.71 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant ΔC10, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant ΔN30 | Plasmodium falciparum | inosine 5'-monophosphate | 54.8 | 2.8 | 19.6 | pH 5, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant ΔN30, inosine 5'-monophosphate |
| IMP-specific 5'-nucleotidase 1 (PfISN1)variant ΔN30 | Plasmodium falciparum | inosine 5'-monophosphate | 28.3 | 29.9 | 0.95 | pH 8, 25 °C | PMID 32591529 | Open record: IMP-specific 5'-nucleotidase 1 (PfISN1) variant ΔN30, inosine 5'-monophosphate |