EC 3.4.11.9: Xaa-Pro aminopeptidase
HydrolasesOpen in Browse
CatLog read 68 records for EC 3.4.11.9 from 5 papers, for 10 organisms. Names in these papers: membrane-bound aminopeptidase P, small aminopeptidase-P (Dr-smAPP), aminopeptidase P (rPfAPP), Icp55ag (intermediate-cleavage peptidase from A. gossypii) and 7 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 38 records for EC 3.4.11.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.11.9 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes | Ashbya gossypii, Fusarium graminearum and 2 more | 24 |
| Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases | Deinococcus radiodurans, Escherichia coli and 2 more | 19 |
| Purification and properties of membrane-bound aminopeptidase P from rat lung | Rattus norvegicus | 12 |
| Evidence for catalytic roles for Plasmodium falciparum aminopeptidase P in the food vacuole and cytosol | Plasmodium falciparum | 7 |
| Investigation of the proton relay system operative in human cystosolic aminopeptidase P | Homo sapiens | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | 16 | 0.14 | 110 | pH 7.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | 88 | 0.97 | 91 | pH 6.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | 160 | 6.7 | 23 | pH 5.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Phe-Pro-His-Phe-Asp | 8.6 | 0.51 | 17 | pH 7.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Phe-Pro-His-Phe-Asp |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Phe-Pro-His-Phe-Asp | 5.4 | 0.86 | 6.3 | pH 5.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Phe-Pro-His-Phe-Asp |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Tyr-Pro-Trp-Thr-Gln | 150 | 1.4 | 110 | pH 7.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Tyr-Pro-Trp-Thr-Gln |
| aminopeptidase P (rPfAPP) | Plasmodium falciparum | Tyr-Pro-Trp-Thr-Gln | 12 | 1.8 | 6.5 | pH 5.5, 37 °C | PMID 19574214 | Open record: aminopeptidase P (rPfAPP), Tyr-Pro-Trp-Thr-Gln |
| aminopeptidase-P (Pf-peptidase) | Pyrococcus furiosus | Met-Ala-Ala | 27 | 0.91 | 30 | pH 7, 97 °C | PMID 30536999 | Open record: aminopeptidase-P (Pf-peptidase), Met-Ala-Ala |
| aminopeptidase-P (Pf-peptidase) | Pyrococcus furiosus | Met-Pro | 102 | 0.8 | 127 | pH 7, 97 °C | PMID 30536999 | Open record: aminopeptidase-P (Pf-peptidase), Met-Pro |
| aminopeptidase-P (Pf-peptidase) | Pyrococcus furiosus | Met-Pro-Ala | 192 | 1.8 | 107 | pH 7, 97 °C | PMID 30536999 | Open record: aminopeptidase-P (Pf-peptidase), Met-Pro-Ala |
| AMPPxc (aminopeptidase P from X. campestris) | Xanthomonas campestris | Met-Ala-Ala | 6.47 | 4.6 | 1.4 calc. | PMID 28476889 | Open record: AMPPxc (aminopeptidase P from X. campestris), Met-Ala-Ala | |
| AMPPxc (aminopeptidase P from X. campestris) | Xanthomonas campestris | Met-Pro-Ala | 29.31 | 0.23 | 130 calc. | PMID 28476889 | Open record: AMPPxc (aminopeptidase P from X. campestris), Met-Pro-Ala | |
| AMPPxc (aminopeptidase P from X. campestris) | Xanthomonas campestris | Tyr-Ala-Ala | 1.14 | 3.85 | 0.296 calc. | PMID 28476889 | Open record: AMPPxc (aminopeptidase P from X. campestris), Tyr-Ala-Ala | |
| human cytosolic aminopeptidase P (hcAMPP) | Homo sapiens | bradykinin | 11 | 0.17 | 65 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP), bradykinin |
| human cytosolic aminopeptidase P (hcAMPP)variant R535A | Homo sapiens | bradykininbradykinin varied 20-1200 µM; 15 min | 0.9 | 0.35 | 2.6 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP) variant R535A, bradykinin |
| human cytosolic aminopeptidase P (hcAMPP)variant R535A | Homo sapiens | bradykinin0.1 mM guanidine hydrochloride (chemical rescue agent) | 2 | 0.327 | 6.1 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP) variant R535A, bradykinin |
| human cytosolic aminopeptidase P (hcAMPP)variant R535A | Homo sapiens | bradykinin1 mM guanidine hydrochloride (chemical rescue agent) | 3.2 | 0.144 | 22 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP) variant R535A, bradykinin |
| human cytosolic aminopeptidase P (hcAMPP)variant R535A | Homo sapiens | bradykinin10 mM guanidine hydrochloride (chemical rescue agent) | 8.3 | 0.163 | 51 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP) variant R535A, bradykinin |
| human cytosolic aminopeptidase P (hcAMPP)variant Y527F | Homo sapiens | bradykinin | 1.8 | 0.2 | 9.2 | pH 7.5, 37 °C | PMID 29351301 | Open record: human cytosolic aminopeptidase P (hcAMPP) variant Y527F, bradykinin |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Leu-Pro-Ala | 173.3 | 3.93 | 44.1 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Leu-Pro-Ala | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Met-Pro-Ala | 294.1 | 2.24 | 131 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Met-Pro-Ala | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Phe-Pro-Ala | 82.01 | 2.57 | 31.9 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Phe-Pro-Ala | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Tyr-Ala-Ala | 2.24 | 0.65 | 3.4 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Tyr-Ala-Ala | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Tyr-Pro-Ala | 14 | 0.24 | 58 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Tyr-Pro-Ala | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Tyr-Ser-Ser | 1.51 | 0.7 | 2.2 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Tyr-Ser-Ser | |
| Icp55ag (intermediate-cleavage peptidase from A. gossypii) | Ashbya gossypii | Tyr-Ser-Ser-Ala-Ala-Ala-Ala | 1.51 | 0.28 | 5.4 calc. | PMID 28476889 | Open record: Icp55ag (intermediate-cleavage peptidase from A. gossypii), Tyr-Ser-Ser-Ala-Ala-Ala-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Leu-Pro-Ala | 93.79 | 1.53 | 61.3 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Leu-Pro-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Met-Pro-Ala | 177.3 | 1.74 | 102 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Met-Pro-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Phe-Pro-Ala | 218.4 | 3.33 | 65.6 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Phe-Pro-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Tyr-Ala-Ala | 6.28 | 1.63 | 3.85 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Tyr-Ala-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Tyr-Pro-Ala | 7.61 | 0.1 | 76 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Tyr-Pro-Ala | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Tyr-Ser-Ser | 1.51 | 0.48 | 3.1 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Tyr-Ser-Ser | |
| Icp55fg (intermediate-cleavage peptidase from F. graminearum) | Fusarium graminearum | Tyr-Ser-Ser-Ala-Ala-Ala-Ala | 1.48 | 0.16 | 9.2 calc. | PMID 28476889 | Open record: Icp55fg (intermediate-cleavage peptidase from F. graminearum), Tyr-Ser-Ser-Ala-Ala-Ala-Ala | |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-homoPro-Pro-Ala-NH2 | 140 | 0.15 | 930 | pH 8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-homoPro-Pro-Ala-NH2 |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Prono MnCl2 | 230 | 0.35 | 660 | pH 8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro4 mM MnCl2 | 180 | 0.36 | 500 | pH 8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro | 150 | 1 | 150 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro-Gly | 17 | 0.03 | 570 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro-Gly |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro-Gly-Phe | 15 | 0.048 | 310 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro-Gly-Phe |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro-Gly-Phe-Ser | 11 | 0.032 | 340 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro-Gly-Phe-Ser |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro-Gly-Phe-Ser-Pro | 16 | 0.051 | 310 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro-Gly-Phe-Ser-Pro |
| membrane-bound aminopeptidase P | Rattus norvegicus | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe | 13 | 0.039 | 330 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe |
| membrane-bound aminopeptidase P | Rattus norvegicus | bradykinin | 12 | 0.021 | 570 | pH 6.8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, bradykinin |
| membrane-bound aminopeptidase P | Rattus norvegicus | Gly-Pro-Hypno MnCl2 | 4.8 | 0.32 | 15 | pH 8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Gly-Pro-Hyp |
| membrane-bound aminopeptidase P | Rattus norvegicus | Gly-Pro-Hyp4 mM MnCl2 | 69 | 2 | 35 | pH 8, 37 °C | PMID 7669781 | Open record: membrane-bound aminopeptidase P, Gly-Pro-Hyp |
| small aminopeptidase-P (Dr-smAPP) | Deinococcus radiodurans | Arg-Pro-Ala | 240 | 2.1 | 114 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP), Arg-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP) | Deinococcus radiodurans | Met-Ala-Ala | 10.5 | 0.15 | 70 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP), Met-Ala-Ala |
| small aminopeptidase-P (Dr-smAPP) | Deinococcus radiodurans | Met-Pro | 97 | 11.9 | 8.15 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP), Met-Pro |
| small aminopeptidase-P (Dr-smAPP) | Deinococcus radiodurans | Met-Pro-Ala | 242 | 1.9 | 127 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP), Met-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant D53A | Deinococcus radiodurans | Arg-Pro-Ala | 29 | 6 | 4.8 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant D53A, Arg-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant D53A | Deinococcus radiodurans | Met-Pro-Ala | 35 | 4 | 8.8 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant D53A, Met-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant R55A | Deinococcus radiodurans | Arg-Pro-Ala | 101 | 3.5 | 29 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant R55A, Arg-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant R55A | Deinococcus radiodurans | Met-Pro-Ala | 144 | 6.1 | 24 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant R55A, Met-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant Y56A | Deinococcus radiodurans | Arg-Pro-Ala | 152 | 8.4 | 18 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant Y56A, Arg-Pro-Ala |
| small aminopeptidase-P (Dr-smAPP)variant Y56A | Deinococcus radiodurans | Met-Pro-Ala | 140 | 3.9 | 36 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Dr-smAPP) variant Y56A, Met-Pro-Ala |
| small aminopeptidase-P (Ec-smAPP) | Escherichia coli | Met-Ala-Ala | 1.5 | 0.23 | 6.5 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Ec-smAPP), Met-Ala-Ala |
| small aminopeptidase-P (Ec-smAPP) | Escherichia coli | Met-Pro | 33 | 7.9 | 4.17 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Ec-smAPP), Met-Pro |
| small aminopeptidase-P (Ec-smAPP) | Escherichia coli | Met-Pro-Ala | 28 | 3 | 9.3 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Ec-smAPP), Met-Pro-Ala |
| small aminopeptidase-P (Mt-smAPP) | Mycobacterium tuberculosis | Met-Ala-Ala | 5 | 0.46 | 11 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Mt-smAPP), Met-Ala-Ala |
| small aminopeptidase-P (Mt-smAPP) | Mycobacterium tuberculosis | Met-Pro | 18 | 6.3 | 2.85 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Mt-smAPP), Met-Pro |
| small aminopeptidase-P (Mt-smAPP) | Mycobacterium tuberculosis | Met-Pro-Ala | 126 | 9 | 14 | pH 8, 55 °C | PMID 30536999 | Open record: small aminopeptidase-P (Mt-smAPP), Met-Pro-Ala |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Leu-Pro-Ala | 302.4 | 2.45 | 123 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Leu-Pro-Ala | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Met-Pro-Ala | 179.4 | 1.62 | 111 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Met-Pro-Ala | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Phe-Pro-Ala | 322 | 3.06 | 105 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Phe-Pro-Ala | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Tyr-Ala-Ala | 29.7 | 4.2 | 7.1 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Tyr-Ala-Ala | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Tyr-Pro-Ala | 41.7 | 0.55 | 76 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Tyr-Pro-Ala | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Tyr-Ser-Ser | 8.2 | 4.91 | 1.7 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Tyr-Ser-Ser | |
| XPNPEP3 (human Xaa-Pro aminopeptidase 3) | Homo sapiens | Tyr-Ser-Ser-Ala-Ala-Ala-Ala | 17.12 | 3.74 | 4.58 calc. | PMID 28476889 | Open record: XPNPEP3 (human Xaa-Pro aminopeptidase 3), Tyr-Ser-Ser-Ala-Ala-Ala-Ala |