EC 3.4.13.22: D-Ala-D-Ala dipeptidase
HydrolasesOpen in Browse
CatLog read 7 records for EC 3.4.13.22 from 1 paper, for 1 organism. Names in these papers: VanX (D-,D-dipeptidase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 15 records for EC 3.4.13.22 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.13.22 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147 | Enterococcus faecium | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-alanine50 mM HEPES pH 8.0; 0.3 µM VanX | 4.7 | 1 | 4.5 | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-alanine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-alaninewith 2 mM Co2+ (CoCl2, optimum concentration) | 69 | 1.2 | 58 | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-alanine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-alaninewith 1 mM Ni2+ (NiSO4, optimum concentration) | 788 | — | — | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-alanine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-alaninewith 3 mM Fe2+ (FeCl2, optimum concentration) | 156 | — | — | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-alanine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-alaninewith 0.5 mM Zn2+ (ZnCl2, optimum concentration) | 30 | — | — | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-alanine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-alanyl-D-serine | 1.8 | 2.8 | 0.64 | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-alanyl-D-serine |
| VanX (D-,D-dipeptidase) | Enterococcus faecium | D-seryl-D-alanine | 0.35 | 1.7 | 0.2 | pH 8, 37 °C | PMID 7873524 | Open record: VanX (D-,D-dipeptidase), D-seryl-D-alanine |