CatLogenzyme kinetics catalog

EC 3.4.13.9: Xaa-Pro dipeptidase

HydrolasesOpen in Browse

CatLog read 33 records for EC 3.4.13.9 from 3 papers, for 3 organisms. Names in these papers: prolidase (proline dipeptidase), prolidase I (PD I), prolidase Ph1prol, patient's prolidase (defective prolidase) and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 46 records for EC 3.4.13.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.13.9 in Browse.

Papers

PaperOrganismsRecords
Characterization of prolidase activity in erythrocytes from a patient with prolidase deficiency: comparison with prolidase I and II purified from normal human erythrocytesHomo sapiens16
Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperaturesPyrococcus furiosus12
Improving the catalytic activity of hyperthermophilic Pyrococcus horikoshii prolidase for detoxification of organophosphorus nerve agents over a broad range of temperaturesPyrococcus horikoshii5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
patient's prolidase (defective prolidase)variant prolidase-deficient patient (mutation not stated)Homo sapiensmethionylprolineno added amino acid (control)—9.89—pH 7.8, 37 °CPMID 16009141Open
patient's prolidase (defective prolidase)variant prolidase-deficient patient (mutation not stated)Homo sapiensmethionylprolinewith 20 mM glycine—4.43—pH 7.8, 37 °CPMID 16009141Open
patient's prolidase (defective prolidase)variant prolidase-deficient patient (mutation not stated)Homo sapiensmethionylprolinewith 20 mM L-valine—5.48—pH 7.8, 37 °CPMID 16009141Open
patient's prolidase (defective prolidase)variant prolidase-deficient patient (mutation not stated)Homo sapiensmethionylprolinewith 20 mM D-valine—6.16—pH 7.8, 37 °CPMID 16009141Open
prolidase (proline dipeptidase)Pyrococcus furiosusL-methionyl-L-proline1236.419pH 7, 35 °CPMID 20422176Open
prolidase (proline dipeptidase)Pyrococcus furiosusL-methionyl-L-proline7675.7135pH 7, 70 °CPMID 20422176Open
prolidase (proline dipeptidase)Pyrococcus furiosusL-methionyl-L-proline21047.95266pH 7, 100 °CPMID 20422176Open
prolidase (proline dipeptidase)variant G39EPyrococcus furiosusL-methionyl-L-proline1671313pH 7, 35 °CPMID 20422176Open
prolidase (proline dipeptidase)variant G39EPyrococcus furiosusL-methionyl-L-proline10176.8150pH 7, 70 °CPMID 20422176Open
prolidase (proline dipeptidase)variant G39EPyrococcus furiosusL-methionyl-L-proline459414.5317pH 7, 100 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/G39E/K71E/S229TPyrococcus furiosusL-methionyl-L-proline1737.922pH 7, 35 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/G39E/K71E/S229TPyrococcus furiosusL-methionyl-L-proline24167.5322pH 7, 70 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/G39E/K71E/S229TPyrococcus furiosusL-methionyl-L-proline748111.1674pH 7, 100 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/K71E/S229TPyrococcus furiosusL-methionyl-L-proline17111.315pH 7, 35 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/K71E/S229TPyrococcus furiosusL-methionyl-L-proline12179.2132pH 7, 70 °CPMID 20422176Open
prolidase (proline dipeptidase)variant R19G/K71E/S229TPyrococcus furiosusL-methionyl-L-proline639613.7467pH 7, 100 °CPMID 20422176Open
prolidase I (PD I)Homo sapiensglycylprolineno added amino acid (control)—2.59—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensglycylprolinewith 20 mM glycine—1.64—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensglycylprolinewith 20 mM L-valine—2.63—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensglycylprolinewith 20 mM D-valine—2.3—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensmethionylprolineno added amino acid (control)—9.2—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensmethionylprolinewith 20 mM glycine—4.11—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensmethionylprolinewith 20 mM L-valine—8.83—pH 7.8, 37 °CPMID 16009141Open
prolidase I (PD I)Homo sapiensmethionylprolinewith 20 mM D-valine—4.65—pH 7.8, 37 °CPMID 16009141Open
prolidase II (PD II)Homo sapiensmethionylprolineno added amino acid (control)—9.64—pH 7.8, 37 °CPMID 16009141Open
prolidase II (PD II)Homo sapiensmethionylprolinewith 20 mM glycine—5.39—pH 7.8, 37 °CPMID 16009141Open
prolidase II (PD II)Homo sapiensmethionylprolinewith 20 mM L-valine—5.65—pH 7.8, 37 °CPMID 16009141Open
prolidase II (PD II)Homo sapiensmethionylprolinewith 20 mM D-valine—6.33—pH 7.8, 37 °CPMID 16009141Open
prolidase Ph1prolPyrococcus horikoshiiLeu-Pro10790.921172pH 7, 70 °CPMID 22162664Open
prolidase Ph1prolvariant A195T/G306SPyrococcus horikoshiiLeu-Pro1.66 × 10³0.812049pH 7, 70 °CPMID 22162664Open
prolidase Ph1prolvariant E127G/E252DPyrococcus horikoshiiLeu-Pro14920.981522pH 7, 70 °CPMID 22162664Open
prolidase Ph1prolvariant E36VPyrococcus horikoshiiLeu-Pro21291.61331pH 7, 70 °CPMID 22162664Open
prolidase Ph1prolvariant Y301C/K342NPyrococcus horikoshiiLeu-Pro28612.92980pH 7, 70 °CPMID 22162664Open