EC 3.4.17.12: carboxypeptidase M
HydrolasesOpen in Browse
CatLog read 44 records for EC 3.4.17.12 from 2 papers, for 1 organism. Names in these papers: carboxypeptidase M.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 6 records for EC 3.4.17.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.17.12 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over | Homo sapiens | 40 |
| Human carboxypeptidase M. Purification and characterization of a membrane-bound carboxypeptidase that cleaves peptide hormones | Homo sapiens | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| carboxypeptidase M | Homo sapiens | Ala-Ser-His-Leu-Gly-Leu-Ala-Arg | 7.4 | 0.033 | 224 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Ala-Ser-His-Leu-Gly-Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | 2.45 | 0.016 | 153 | pH 7, 37 °C | PMID 2914904 | Open record: carboxypeptidase M, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| carboxypeptidase M | Homo sapiens | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | 30 | 0.0277 | 1076 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Ala-Argnative; purified from human seminal plasma prostasomes | 88 | 0.18 | 487 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Ala-Argsecreted from Pichia pastoris X-33 | 107 | 0.162 | 661 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Ala-Arg | 77 | 0.115 | 675 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Asn-Arg | 35 | 0.343 | 103 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Asn-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Gln-Arg | 22 | 0.127 | 173 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gln-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Gly-Argnative; purified from human seminal plasma prostasomes | 6.07 | 0.29 | 21 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gly-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Gly-Argsecreted from Pichia pastoris X-33 | 5.7 | 0.255 | 22 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gly-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Gly-Arg | 3.9 | 0.289 | 13 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gly-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Gly-Lysnative; purified from human seminal plasma prostasomes | 9.6 | 10.14 | 0.9 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gly-Lys |
| carboxypeptidase M | Homo sapiens | benzoyl-Gly-Lyssecreted from Pichia pastoris X-33 | 11 | 10.65 | 1 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Gly-Lys |
| carboxypeptidase M | Homo sapiens | benzoyl-His-Arg | 14 | 0.239 | 58 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-His-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Ile-Arg | 1 | 0.205 | 5 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Ile-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Leu-Arg | 19 | 0.168 | 111 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Leu-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Met-Argnative; purified from human seminal plasma prostasomes | 112 | 0.137 | 817 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Met-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Met-Argsecreted from Pichia pastoris X-33 | 130 | 0.13 | 1001 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Met-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Met-Arg | 87 | 0.138 | 632 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Met-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Phe-Arg | 33 | 0.0584 | 561 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Phe-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Ser-Arg | 60 | 0.219 | 274 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Ser-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Thr-Arg | 22.9 | 0.192 | 119 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Thr-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Trp-Arg | 23 | 0.069 | 329 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Trp-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Tyr-Arg | 27 | 0.048 | 560 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Tyr-Arg |
| carboxypeptidase M | Homo sapiens | benzoyl-Val-Arg | 7.7 | 0.264 | 29 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, benzoyl-Val-Arg |
| carboxypeptidase M | Homo sapiens | dansyl-Ala-Argnative; purified from human seminal plasma prostasomes | 17.6 | 0.073 | 242 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, dansyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | dansyl-Ala-Argsecreted from Pichia pastoris X-33 | 17 | 0.083 | 205 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, dansyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | furylacryloyl-Ala-Argnative; purified from human seminal plasma prostasomes | 32 | 0.068 | 465 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, furylacryloyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | furylacryloyl-Ala-Argsecreted from Pichia pastoris X-33 | 40 | 0.09 | 442 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, furylacryloyl-Ala-Arg |
| carboxypeptidase M | Homo sapiens | furylacryloyl-Ala-Lys | 11 | 1.152 | 9 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, furylacryloyl-Ala-Lys |
| carboxypeptidase M | Homo sapiens | Gly-Gly-Arg | 1.9 | 1.181 | 1.6 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Gly-Gly-Arg |
| carboxypeptidase M | Homo sapiens | Gly-Leu-Ala-Arg | 8.2 | 0.05 | 164 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Gly-Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | hippuryl-argininic acid (benzoylglycyl ester of argininic acid)native; purified from human seminal plasma prostasomes | 273 | 0.049 | 5573 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, hippuryl-argininic acid (benzoylglycyl ester of argininic acid) |
| carboxypeptidase M | Homo sapiens | hippuryl-argininic acid (benzoylglycyl ester of argininic acid)secreted from Pichia pastoris X-33 | 316 | 0.046 | 6876 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, hippuryl-argininic acid (benzoylglycyl ester of argininic acid) |
| carboxypeptidase M | Homo sapiens | His-Leu-Gly-Leu-Ala-Arg | 6.6 | 0.028 | 235 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, His-Leu-Gly-Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | Leu-Ala-Arg | 4.2 | 0.027 | 155 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | Leu-Gly-Leu-Ala-Arg | 6.1 | 0.041 | 148 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Leu-Gly-Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | p-hydroxybenzoyl-Gly-Argnative; purified from human seminal plasma prostasomes | 5.7 | 0.241 | 24 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, p-hydroxybenzoyl-Gly-Arg |
| carboxypeptidase M | Homo sapiens | p-hydroxybenzoyl-Gly-Argsecreted from Pichia pastoris X-33 | 4.9 | 0.206 | 24 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, p-hydroxybenzoyl-Gly-Arg |
| carboxypeptidase M | Homo sapiens | Pro-Gly-Lys-Ala-Arg | 11 | 0.035 | 313 | pH 7.2, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Pro-Gly-Lys-Ala-Arg |
| carboxypeptidase M | Homo sapiens | Ser-His-Leu-Gly-Leu-Ala-Arg | 6.7 | 0.051 | 131 | pH 7.4, 37 °C | PMID 17208058 | Open record: carboxypeptidase M, Ser-His-Leu-Gly-Leu-Ala-Arg |
| carboxypeptidase M | Homo sapiens | Tyr-Gly-Gly-Phe-Leu-Arg | 1.77 | 0.063 | 28 | pH 7, 37 °C | PMID 2914904 | Open record: carboxypeptidase M, Tyr-Gly-Gly-Phe-Leu-Arg |
| carboxypeptidase M | Homo sapiens | Tyr-Gly-Gly-Phe-Met-Arg | 15.57 | 0.046 | 338 | pH 7, 37 °C | PMID 2914904 | Open record: carboxypeptidase M, Tyr-Gly-Gly-Phe-Met-Arg |
| carboxypeptidase M | Homo sapiens | Tyr-Gly-Gly-Phe-Met-Lys | 11.05 | 0.375 | 30 | pH 7, 37 °C | PMID 2914904 | Open record: carboxypeptidase M, Tyr-Gly-Gly-Phe-Met-Lys |