CatLogenzyme kinetics catalog

EC 3.4.17.21: glutamate carboxypeptidase II

HydrolasesOpen in Browse

CatLog read 4 records for EC 3.4.17.21 from 1 paper, for 2 organisms. Names in these papers: glutamate carboxypeptidase II (GCPII), human (Avi-hGCPII), glutamate carboxypeptidase II (GCPII), mouse (Avi-mGCPII).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 18 records for EC 3.4.17.21 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.17.21 in Browse.

Papers

PaperOrganismsRecords
Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPIIHomo sapiens, Mus musculus4

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
glutamate carboxypeptidase II (GCPII), human (Avi-hGCPII)Homo sapiensN-acetyl-L-aspartyl-L-glutamate1.455.5 × 10⁻⁴2.65 × 10³pH 7.4PMID 28904865Open
glutamate carboxypeptidase II (GCPII), human (Avi-hGCPII)Homo sapienspteroyl-di-L-glutamate5.093.9 × 10⁻⁵1.32 × 10⁵pH 7.4, 37 °CPMID 28904865Open
glutamate carboxypeptidase II (GCPII), mouse (Avi-mGCPII)Mus musculusN-acetyl-L-aspartyl-L-glutamate1.440.0019770pH 7.4PMID 28904865Open
glutamate carboxypeptidase II (GCPII), mouse (Avi-mGCPII)Mus musculuspteroyl-di-L-glutamate3.632.9 × 10⁻⁴1.26 × 10⁴pH 7.4, 37 °CPMID 28904865Open