EC 3.4.17.22: metallocarboxypeptidase D
HydrolasesOpen in Browse
CatLog read 9 records for EC 3.4.17.22 from 2 papers, for 2 organisms. Names in these papers: carboxypeptidase D (rhCPD), gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170, gp180 (duck metallocarboxypeptidase D homolog), truncated form gp120, gp180 (duck metallocarboxypeptidase D homolog), truncated form gp60-120 and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 5 records for EC 3.4.17.22 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.17.22 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity | duck | 6 |
| Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains | Homo sapiens | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| carboxypeptidase D (rhCPD) | Homo sapiens | Dansyl-Phe-Ala-Arg | 12.5 | 0.153 | 82 | pH 6.5, 37 °C | PMID 29131831 | Open record: carboxypeptidase D (rhCPD), Dansyl-Phe-Ala-Arg |
| carboxypeptidase D (rhCPD)variant E350Q (Active domain II rhCPD) | Homo sapiens | Dansyl-Phe-Ala-Arg | 7 | 0.844 | 8 | pH 6.5, 37 °C | PMID 29131831 | Open record: carboxypeptidase D (rhCPD) variant E350Q (Active domain II rhCPD), Dansyl-Phe-Ala-Arg |
| carboxypeptidase D (rhCPD)variant E762Q (Active domain I rhCPD) | Homo sapiens | Dansyl-Phe-Ala-Arg | 8.5 | 0.319 | 27 | pH 6.5, 37 °C | PMID 29131831 | Open record: carboxypeptidase D (rhCPD) variant E762Q (Active domain I rhCPD), Dansyl-Phe-Ala-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg | 57 | 0.012 | 4.7 × 10³ | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170, 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Phe-Arg | 17 | 0.021 | 800 | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170, 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Phe-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Pro-Ala-Arg | 57 | 0.017 | 3.4 × 10³ | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), soluble form gp170, 5-dimethylaminonaphthalene-1-sulfonyl-Pro-Ala-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), truncated form gp120 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg | 22 | 0.014 | 1.6 × 10³ | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), truncated form gp120, 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), truncated form gp60-120 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg | 22 | 0.026 | 830 | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), truncated form gp60-120, 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg |
| gp180 (duck metallocarboxypeptidase D homolog), truncated form gp75 | duck | 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg | 9.2 | 0.082 | 110 | pH 5.5, 37 °C | PMID 9525948 | Open record: gp180 (duck metallocarboxypeptidase D homolog), truncated form gp75, 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Ala-Arg |