EC 3.4.21.70: Pancreatic endopeptidase E

HydrolasesOpen in Browse

CatLog read 15 records for EC 3.4.21.70 from 2 papers, for 1 organism. Names in these papers: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), elastase 3B (ELA3B), elastase 3A (ELA3A).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 3.4.21.70 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.21.70 in Browse.

Papers

Papers with records for EC 3.4.21.70
Paper	Organisms	Records
Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes	Homo sapiens	12
Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen	Homo sapiens	3

Records

Records for EC 3.4.21.70 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide	22.9	1.089	21	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-isoleucine 4-nitroanilide	0.99	1.06	0.93	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-isoleucine 4-nitroanilide
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-leucine 4-nitroanilide	1.16	0.722	1.6	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-leucine 4-nitroanilide
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-methionine 4-nitroanilide	0.24	0.452	0.53	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-methionine 4-nitroanilide
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-serine 4-nitroanilide	0.14	1.447	0.099	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-serine 4-nitroanilide
chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide	2.44	1.178	2.1	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3A (CELA3A, human pancreatic elastase 3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide	24.8	0.374	66	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-isoleucine 4-nitroanilide	1.25	0.484	2.6	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-isoleucine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-leucine 4-nitroanilide	1.01	0.259	3.9	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-leucine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-methionine 4-nitroanilide	0.24	0.288	0.83	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-methionine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-serine 4-nitroanilide	0.26	0.984	0.26	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-serine 4-nitroanilide
chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide	3.66	0.43	8.5	pH 8, 22 °C	PMID 28062577	Open record: chymotrypsin-like elastase 3B (CELA3B, human pancreatic elastase 3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide
elastase 3A (ELA3A)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide	5.5	2.435	2.3	pH 8	PMID 23035638	Open record: elastase 3A (ELA3A), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide
elastase 3B (ELA3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide	18.9	0.7851	24	pH 8	PMID 23035638	Open record: elastase 3B (ELA3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide
elastase 3B (ELA3B)	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide	4.9	2.979	1.6	pH 8	PMID 23035638	Open record: elastase 3B (ELA3B), N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide