EC 3.4.22.15: cathepsin L
HydrolasesOpen in Browse
CatLog read 110 records for EC 3.4.22.15 from 3 papers, for 4 organisms. Names in these papers: cathepsin L, cathepsin L protease FhCatL5, cathepsin L protease FgCatL1G, brucipain (TbbCATL, cathepsin L-like cysteine protease).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 27 records for EC 3.4.22.15 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.22.15 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L | Homo sapiens | 71 |
| Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles | Fasciola gigantica, Fasciola hepatica | 31 |
| Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L | Trypanosoma brucei brucei | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin | 0.52 | 4.6 × 10⁻⁴ | 1187 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin | 1.01 | 3.3 × 10⁻⁴ | 3148 | pH 6.5, 37 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin1 μg/mL heparan | 0.52 | 4.4 × 10⁻⁴ | 1119 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin5 μg/mL heparan | 0.46 | 4.1 × 10⁻⁴ | 1121 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin10 μg/mL heparan | 0.39 | 3.7 × 10⁻⁴ | 1088 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin20 μg/mL heparan | 0.43 | 4.7 × 10⁻⁴ | 999.8 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-valine-leucine-arginine-7-amino-4-methylcoumarin | 0.89 | 0.01242 | 71.9 | pH 6.5, 25 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-valine-leucine-arginine-7-amino-4-methylcoumarin |
| brucipain (TbbCATL, cathepsin L-like cysteine protease) | Trypanosoma brucei brucei | benzyloxycarbonyl-valine-leucine-arginine-7-amino-4-methylcoumarin | 1.07 | 0.00695 | 155.3 | pH 6.5, 37 °C | PMID 22234330 | Open record: brucipain (TbbCATL, cathepsin L-like cysteine protease), benzyloxycarbonyl-valine-leucine-arginine-7-amino-4-methylcoumarin |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Ala-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 5.3 | 4.5 × 10⁻⁴ | 11,778 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Ala-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Arg-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.8 | 1.6 × 10⁻⁴ | 2.375 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Arg-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Asn-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.5 | 7.1 × 10⁻⁴ | 4.93 × 10³ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Asn-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Gln-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.8 | 7.5 × 10⁻⁴ | 5067 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Gln-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Glu-Glu-epsilon-aminocaproyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 0.0025 | 160 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Glu-Glu-epsilon-aminocaproyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Glu-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4 | 0.0022 | 1818 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Glu-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.2 | 0.0011 | 1091 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Gly-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.1 | 0.0023 | 43 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Gly-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 2.41 × 10³ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-His-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 5.9 | 3.5 × 10⁻⁴ | 16,857 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-His-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Ile-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.3 | 2.3 × 10⁻⁴ | 1 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Ile-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Leu-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 5385 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Leu-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Arg-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.2 | 0.0026 | 1231 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Arg-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Asn-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 0.005 | 80 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Asn-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Asp-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 0.035 | 11 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Asp-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Gln-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.7 | 0.0085 | 200 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Gln-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Glu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 0.0097 | 52 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Glu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Gly-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.5 | 0.0096 | 52 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Gly-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-His-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.3 | 0.0034 | 382 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-His-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Ile-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.3 | 1.7 × 10⁻⁴ | 13,529 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Ile-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Ala-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.1 | 9.5 × 10⁻⁴ | 1158 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Ala-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Arg-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.7 | 1.8 × 10⁻⁴ | 20,556 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Arg-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Asn-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 6.3 | 2 × 10⁻⁴ | 3.15 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Asn-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Gln-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 5.8 | 2.7 × 10⁻⁴ | 21,481 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Gln-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Glu-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.9 | 0.0017 | 2882 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Glu-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Gly-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.4 | 1.7 × 10⁻⁴ | 2 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Gly-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-His-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 7.3 | 2 × 10⁻⁴ | 3.65 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-His-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ile-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.9 | 4 × 10⁻⁴ | 9.75 × 10³ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ile-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Leu-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 16,923 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Leu-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Phe-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 4.9 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Phe-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ala-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.1 | 2.3 × 10⁻⁴ | 17,826 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ala-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Arg-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.6 | 1.7 × 10⁻⁴ | 21,176 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Arg-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Asn-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.3 | 1.9 × 10⁻⁴ | 12,105 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Asn-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Gln-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.2 | 1.9 × 10⁻⁴ | 22,105 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Gln-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Glu-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.1 | 7.2 × 10⁻⁴ | 5694 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Glu-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Gly-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.8 | 2.4 × 10⁻⁴ | 2 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Gly-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-His-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.7 | 1.4 × 10⁻⁴ | 26,429 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-His-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ile-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.4 | 1.3 × 10⁻⁴ | 18,461 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ile-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Leu-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 2.647 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Leu-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Phe-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 2.5 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Phe-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Pro-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 6 | 3.5 × 10⁻⁴ | 17,143 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Pro-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4.6 | 1.5 × 10⁻⁴ | 30,667 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Val-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.2 | 1.3 × 10⁻⁴ | 24,615 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Ser-Val-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Arg-Val-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 5.5 | 2.3 × 10⁻⁴ | 23,913 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Arg-Val-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Asn-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.1 | 0.0015 | 733 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Asn-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Asp-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.2 | 0.0038 | 53 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Asp-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Gln-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.9 | 5.6 × 10⁻⁴ | 1607 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Gln-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Glu-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.6 | 0.0055 | 473 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Glu-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Gly-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 2.6 × 10⁻⁴ | 1538 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Gly-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-His-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.3 | 2.1 × 10⁻⁴ | 6.19 × 10³ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-His-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Ile-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 1.7 × 10⁻⁴ | 2353 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Ile-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Leu-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 2 × 10³ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Leu-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Lys-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 3.1 | 1.7 × 10⁻⁴ | 18,235 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Lys-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Met-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 4.7 × 10⁻⁴ | 851 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Met-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Phe-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 6176 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Phe-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Pro-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.1 | 0.006 | 17 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Pro-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Ser-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.5 | 0.0011 | 1364 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Ser-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Thr-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.3 | 5.5 × 10⁻⁴ | 2364 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Thr-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Leu-Val-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.5 | 2.8 × 10⁻⁴ | 1786 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Leu-Val-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Lys-epsilon-aminocaproyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.9 | 6 × 10⁻⁴ | 3167 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Lys-epsilon-aminocaproyl-Glu-Leu-Lys-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Met-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 4 | 0.0028 | 1429 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Met-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Phe-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 13.5 | 2.6 × 10⁻⁴ | 51,923 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Phe-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Pro-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.2 | 0.0067 | 179 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Pro-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Ser-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.9 | 0.012 | 158 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Ser-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Thr-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.4 | 0.0049 | 82 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Thr-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Trp-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 1.9 | 0.0038 | 500 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Trp-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Tyr-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 7.8 | 4.2 × 10⁻⁴ | 18,571 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Tyr-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Lys-Val-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 6.4 | 5.9 × 10⁻⁴ | 10,847 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Lys-Val-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Met-Ile-Ser-Leu-Met-Lys-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 1015 | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Met-Ile-Ser-Leu-Met-Lys-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Phe-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 1 × 10⁴ | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Phe-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L | Homo sapiens | ortho-aminobenzoyl-Val-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 2.1 | — | — | pH 5.5, 37 °C | PMID 15369827 | Open record: cathepsin L, ortho-aminobenzoyl-Val-Leu-Arg-Ser-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Boc-Ala-Gly-Pro-Arg-AMC | — | — | 33.8 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Boc-Ala-Gly-Pro-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Boc-Asp-Pro-Arg-AMC | — | — | 11.3 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Boc-Asp-Pro-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Boc-Val-Leu-Lys-AMC | — | — | 6.75 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Boc-Val-Leu-Lys-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Boc-Val-Pro-Arg-AMC | — | — | 5.01 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Boc-Val-Pro-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Bz-Phe-Val-Arg-AMC | — | — | 18.1 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Bz-Phe-Val-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | D-Val-Leu-Arg-AMC | — | — | 38.3 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, D-Val-Leu-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Tosyl-Gly-Pro-Arg-AMCvaried substrate | 1.87 | 0.08953 | 20.9 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Tosyl-Gly-Pro-Arg-AMC4% DMSO | — | — | 38.5 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FgCatL1G | Fasciola gigantica | Z-Phe-Arg-AMC | 0.51 | 0.07469 | 6.78 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FgCatL1G, Z-Phe-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Boc-Ala-Gly-Pro-Arg-AMC | — | — | 16.6 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Boc-Ala-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Boc-Asp-Pro-Arg-AMC | — | — | 10.1 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Boc-Asp-Pro-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Boc-Val-Leu-Lys-AMC | — | — | 7.22 × 10³ | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Boc-Val-Leu-Lys-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Boc-Val-Pro-Arg-AMC | — | — | 22.4 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Boc-Val-Pro-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Bz-Phe-Val-Arg-AMC | — | — | 781 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Bz-Phe-Val-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | D-Val-Leu-Arg-AMC | — | — | 5.42 × 10³ | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, D-Val-Leu-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Pro-Phe-Arg-AMC | — | — | 149 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Pro-Phe-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMCvaried substrate | 0.84 | 0.05392 | 15.5 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC4% DMSO | — | — | 24.4 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Z-Phe-Arg-AMCvaried substrate | 17.89 | 0.02481 | 721 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Z-Phe-Arg-AMC |
| cathepsin L protease FhCatL5 | Fasciola hepatica | Z-Phe-Arg-AMC4% DMSO | — | — | 474 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5, Z-Phe-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Boc-Ala-Gly-Pro-Arg-AMC | — | — | 119 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Boc-Ala-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Boc-Asp-Pro-Arg-AMC | — | — | 75.2 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Boc-Asp-Pro-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Boc-Val-Leu-Lys-AMC | — | — | 1.39 × 10³ | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Boc-Val-Leu-Lys-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Boc-Val-Pro-Arg-AMC | — | — | 52.7 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Boc-Val-Pro-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Bz-Phe-Val-Arg-AMC | — | — | 182 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Bz-Phe-Val-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | D-Val-Leu-Arg-AMC | — | — | 308 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, D-Val-Leu-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Pro-Phe-Arg-AMC | — | — | 211 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Pro-Phe-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMCvaried substrate | 1.34 | 0.0786 | 17 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC4% DMSO | — | — | 84.3 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Z-Phe-Arg-AMCvaried substrate | 11.05 | 0.1373 | 80.5 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Z-Phe-Arg-AMC |
| cathepsin L protease FhCatL5variant L69W | Fasciola hepatica | Z-Phe-Arg-AMC4% DMSO | — | — | 152 | pH 5.5, 37 °C | PMID 21167899 | Open record: cathepsin L protease FhCatL5 variant L69W, Z-Phe-Arg-AMC |