EC 3.4.22.38: cathepsin K
HydrolasesOpen in Browse
CatLog read 28 records for EC 3.4.22.38 from 2 papers, for 1 organism. Names in these papers: cathepsin K.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 13 records for EC 3.4.22.38 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.22.38 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Development of Cathepsin B‑Activatable Cell-Penetrating Peptides for Tumor Targeting | Homo sapiens | 16 |
| Structure-activity analysis of cathepsin K/chondroitin 4-sulfate interactions | Homo sapiens | 12 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| cathepsin K | Homo sapiens | Abz-G-F-L-Cit-A-K(Dnp)-Sar-V-CONH2 (compound 56) | — | — | 394 | PMID 41988367 | Open record: cathepsin K, Abz-G-F-L-Cit-A-K(Dnp)-Sar-V-CONH2 (compound 56) | |
| cathepsin K | Homo sapiens | Abz-G-F-L-Cit-A-Lys(Dnp)-Sar-V-CONH2 (compound 56) | — | — | 394 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-F-L-Cit-A-Lys(Dnp)-Sar-V-CONH2 (compound 56) |
| cathepsin K | Homo sapiens | Abz-G-F-L-G-F-K(Dnp)-Sar-V-CONH2 (compound 66) | — | — | 283 | PMID 41988367 | Open record: cathepsin K, Abz-G-F-L-G-F-K(Dnp)-Sar-V-CONH2 (compound 66) | |
| cathepsin K | Homo sapiens | Abz-G-F-L-G-F-Lys(Dnp)-Sar-V-CONH2 (compound 66) | — | — | 283 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-F-L-G-F-Lys(Dnp)-Sar-V-CONH2 (compound 66) |
| cathepsin K | Homo sapiens | Abz-G-I-F(3-Me)-R(ec)-A-K(Dnp)-Sar-V-CONH2 (compound 64) | — | — | 23 | PMID 41988367 | Open record: cathepsin K, Abz-G-I-F(3-Me)-R(ec)-A-K(Dnp)-Sar-V-CONH2 (compound 64) | |
| cathepsin K | Homo sapiens | Abz-G-I-F(3-Me)-R(ec)-A-Lys(Dnp)-Sar-V-CONH2 (compound 64) | — | — | 23 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-I-F(3-Me)-R(ec)-A-Lys(Dnp)-Sar-V-CONH2 (compound 64) |
| cathepsin K | Homo sapiens | Abz-G-I-V-R(ec)-A-K(Dnp)-Sar-V-CONH2 (compound 63) | — | — | 68 | PMID 41988367 | Open record: cathepsin K, Abz-G-I-V-R(ec)-A-K(Dnp)-Sar-V-CONH2 (compound 63) | |
| cathepsin K | Homo sapiens | Abz-G-I-V-R(ec)-A-Lys(Dnp)-Sar-V-CONH2 (compound 63) | — | — | 68 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-I-V-R(ec)-A-Lys(Dnp)-Sar-V-CONH2 (compound 63) |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-I)-G-A-K(Dnp)-Sar-V-CONH2 (compound 55) | — | — | 34 | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-I)-G-A-K(Dnp)-Sar-V-CONH2 (compound 55) | |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-I)-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 55) | — | — | 34 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-I)-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 55) |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-Me)-Cit-A-K(Dnp)-Sar-V-CONH2 (compound 60) | — | — | 395 | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-Me)-Cit-A-K(Dnp)-Sar-V-CONH2 (compound 60) | |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-Me)-Cit-A-Lys(Dnp)-Sar-V-CONH2 (compound 60) | — | — | 395 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-Me)-Cit-A-Lys(Dnp)-Sar-V-CONH2 (compound 60) |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-Me)-G-A-K(Dnp)-Sar-V-CONH2 (compound 54) | — | — | 180 | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-Me)-G-A-K(Dnp)-Sar-V-CONH2 (compound 54) | |
| cathepsin K | Homo sapiens | Abz-G-L-F(3-Me)-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 54) | — | — | 180 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F(3-Me)-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 54) |
| cathepsin K | Homo sapiens | Abz-G-L-F-G-A-K(Dnp)-Sar-V-CONH2 (compound 53) | — | — | 920 | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F-G-A-K(Dnp)-Sar-V-CONH2 (compound 53) | |
| cathepsin K | Homo sapiens | Abz-G-L-F-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 53) | — | — | 920 | pH 6, 37 °C | PMID 41988367 | Open record: cathepsin K, Abz-G-L-F-G-A-Lys(Dnp)-Sar-V-CONH2 (compound 53) |
| cathepsin K | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 2.9 | 0.048 | 60 | pH 5.5 | PMID 21193413 | Open record: cathepsin K, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin K | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 6.2 | 0.0033 | 1.9 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 2 | 0.034 | 59 | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 5.7 | 0.0035 | 1.6 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/I171E/Q172S | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 2.1 | 0.037 | 57 | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/I171E/Q172S, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/I171E/Q172S | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 6.4 | 0.0024 | 2.7 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/I171E/Q172S, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/I171E/Q172S/N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 3.6 | 0.058 | 62 | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/I171E/Q172S/N190M/K191G/L195K, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/I171E/Q172S/N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 5.6 | 0.0037 | 1.5 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/I171E/Q172S/N190M/K191G/L195K, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 1.9 | 0.043 | 44 | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/N190M/K191G/L195K, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant K9E/N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 7.6 | 0.0037 | 2.1 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant K9E/N190M/K191G/L195K, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide | 3.7 | 0.038 | 97 | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant N190M/K191G/L195K, benzyloxycarbonyl-glycyl-L-prolyl-L-arginine 4-methyl-7-coumarylamide |
| cathepsin Kvariant N190M/K191G/L195K | Homo sapiens | benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide | 9.1 | 0.0046 | 2 × 10³ | pH 5.5 | PMID 21193413 | Open record: cathepsin K variant N190M/K191G/L195K, benzyloxycarbonyl-L-leucyl-L-arginine 4-methyl-7-coumarylamide |