EC 3.4.22.40: bleomycin hydrolase
HydrolasesOpen in Browse
CatLog read 7 records for EC 3.4.22.40 from 1 paper, for 1 organism. Names in these papers: recombinant human bleomycin hydrolase (rhBLMH).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 9 records for EC 3.4.22.40 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.22.40 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Activities of recombinant human bleomycin hydrolase on bleomycins and engineered analogues revealing new opportunities to overcome bleomycin-induced pulmonary toxicity | Homo sapiens | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | 6′-deoxy bleomycin A2 | 4.9 | 0.805 | 6.1 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), 6′-deoxy bleomycin A2 |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | 6′-deoxy bleomycin Z | 15 | 0.942 | 16 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), 6′-deoxy bleomycin Z |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | 6′-deoxy tallysomycin H-1 | 2.5 | 0.72 | 3.5 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), 6′-deoxy tallysomycin H-1 |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | bleomycin A2 | 4 | 0.592 | 6.7 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), bleomycin A2 |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | bleomycin B2 | 11 | 0.19 | 58 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), bleomycin B2 |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | bleomycin Z | 9.8 | 0.854 | 11 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), bleomycin Z |
| recombinant human bleomycin hydrolase (rhBLMH) | Homo sapiens | tallysomycin H1 | 2.4 | 0.743 | 3.2 | pH 7.5, 30 °C | PMID 29730026 | Open record: recombinant human bleomycin hydrolase (rhBLMH), tallysomycin H1 |