CatLogenzyme kinetics catalog

EC 3.4.22.46: L-peptidase

HydrolasesOpen in Browse

CatLog read 5 records for EC 3.4.22.46 from 1 paper, for 1 organism. Names in these papers: papain-like protease (PLpro).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 2 records for EC 3.4.22.46 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.22.46 in Browse.

Papers

PaperOrganismsRecords
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirussevere acute respiratory syndrome coronavirus5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
papain-like protease (PLpro)severe acute respiratory syndrome coronavirusDabcyl-FRLKGGAPIKGV-Edans0.130.02275.7pH 6.2, 30 °CPMID 18313035Open
papain-like protease (PLpro)severe acute respiratory syndrome coronavirusDabcyl-FRLKGGAPIKGV-Edans0.110.02524.4pH 6.8, 30 °CPMID 18313035Open
papain-like protease (PLpro)severe acute respiratory syndrome coronavirusDabcyl-FRLKGGAPIKGV-Edans0.060.01743.4pH 8, 30 °CPMID 18313035Open
papain-like protease (PLpro)severe acute respiratory syndrome coronavirusDabcyl-FRLKGGAPIKGV-Edans6-mercaptopurine (6MP)0.130.02325.630 °CPMID 18313035Open
papain-like protease (PLpro)severe acute respiratory syndrome coronavirusDabcyl-FRLKGGAPIKGV-Edans6-thioguanine (6TG)0.140.02156.530 °CPMID 18313035Open