EC 3.4.24.36: leishmanolysin
HydrolasesOpen in Browse
CatLog read 9 records for EC 3.4.24.36 from 1 paper, for 1 organism. Names in these papers: GP63 surface metalloproteinase (leishmanolysin, LdGP63).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 3 records for EC 3.4.24.36 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.24.36 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The effect of C-terminal domain deletion on the catalytic activity of Leishmania donovani surface proteinase GP63: Role of Ser446 in proteolysis | Leishmania donovani | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| GP63 surface metalloproteinase (leishmanolysin, LdGP63) | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 12 | 0.0037 | 3.2 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63), dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant F448V | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 12.7 | 0.005 | 2.5 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant F448V, dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant F448Y | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 11.8 | 0.0052 | 2.2 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant F448Y, dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant S446A | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 3.1 | 0.0098 | 300 | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant S446A, dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant S446T | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 11.9 | 0.0054 | 2.2 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant S446T, dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant Δ389 (residues 1-388) | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 3.5 | 0.0104 | 300 | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant Δ389 (residues 1-388), dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant Δ420 (residues 1-419) | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 3.7 | 0.011 | 300 | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant Δ420 (residues 1-419), dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant Δ484 (residues 1-483) | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 11.1 | 0.0055 | 2 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant Δ484 (residues 1-483), dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |
| GP63 surface metalloproteinase (leishmanolysin, LdGP63)variant Δ542 (residues 1-541) | Leishmania donovani | dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 | 11.8 | 0.0053 | 2.2 × 10³ | 25 °C | PMID 20678540 | Open record: GP63 surface metalloproteinase (leishmanolysin, LdGP63) variant Δ542 (residues 1-541), dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 |