EC 3.4.24.63: meprin B
HydrolasesOpen in Browse
CatLog read 11 records for EC 3.4.24.63 from 2 papers, for 2 organisms. Names in these papers: meprin B, meprin β.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 7 records for EC 3.4.24.63 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.24.63 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity | Mus musculus | 9 |
| Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis | Homo sapiens | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| meprin B | Mus musculus | Gastrin 17 | 12.4 | 0.0071 | 1.75 × 10³ | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Gastrin 17 |
| meprin B | Mus musculus | gastrin-releasing peptide fragment 14-27 | 12.6 | 0.0481 | 262 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, gastrin-releasing peptide fragment 14-27 |
| meprin B | Mus musculus | Glucagon | 26.8 | 0.22 | 134 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Glucagon |
| meprin B | Mus musculus | human secretin | — | — | 13.3 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, human secretin |
| meprin B | Mus musculus | Kinetensin | — | — | 36.3 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Kinetensin |
| meprin B | Mus musculus | Neuropeptide Y | — | — | 60.9 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Neuropeptide Y |
| meprin B | Mus musculus | Orcokinin | 23.4 | 0.1 | 234 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Orcokinin |
| meprin B | Mus musculus | Peptide YY | — | — | 51.3 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, Peptide YY |
| meprin B | Mus musculus | sulfated cholecystokinin octapeptide amide (DY(SO3H)MGWMDF-NH2) | 13.9 | 0.211 | 65.7 | pH 7.5, 37 °C | PMID 11278902 | Open record: meprin B, sulfated cholecystokinin octapeptide amide (DY(SO3H)MGWMDF-NH2) |
| meprin β | Homo sapiens | Lys-Lys-Gly-Tyr-Val-Ala-Asp-Ala-Pro-7-amido-4-methylcoumarin | 4 | 0.074 | 60 | pH 7.5, 30 °C | PMID 30098994 | Open record: meprin β, Lys-Lys-Gly-Tyr-Val-Ala-Asp-Ala-Pro-7-amido-4-methylcoumarin |
| meprin β | Homo sapiens | Lys-Lys-Gly-Tyr-Val-Ala-Asp-Ala-Pro-p-nitroanilide | 20 | 0.184 | 106 | pH 7.5, 30 °C | PMID 30098994 | Open record: meprin β, Lys-Lys-Gly-Tyr-Val-Ala-Asp-Ala-Pro-p-nitroanilide |