EC 3.4.25.1: proteasome endopeptidase complex
HydrolasesOpen in Browse
CatLog read 8 records for EC 3.4.25.1 from 1 paper, for 2 organisms. Names in these papers: 20 S proteasome.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 9 records for EC 3.4.25.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.25.1 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biochemical analysis of the 20 S proteasome of Trypanosoma brucei | Homo sapiens, Trypanosoma brucei | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 20 S proteasome | Homo sapiens | acetyl-Glu-Pro-Phe-Asp-7-amino-4-carbamoylcoumarin | 17.16 | 0.032 | 532.5 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-Glu-Pro-Phe-Asp-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Homo sapiens | acetyl-His-His-Ser-Leu-7-amino-4-carbamoylcoumarin | 36.3 | 0.36 | 98.5 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-His-His-Ser-Leu-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Homo sapiens | acetyl-norleucyl-Arg-norleucyl-Arg-7-amino-4-carbamoylcoumarin | 5.34 | 0.11 | 50.6 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-norleucyl-Arg-norleucyl-Arg-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Homo sapiens | acetyl-Tyr-Trp-Thr-Gln-7-amino-4-carbamoylcoumarin | 0.27 | 0.027 | 9.8 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-Tyr-Trp-Thr-Gln-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Trypanosoma brucei | acetyl-Glu-Pro-Phe-Asp-7-amino-4-carbamoylcoumarin | 2.7 | 0.088 | 31.1 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-Glu-Pro-Phe-Asp-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Trypanosoma brucei | acetyl-His-His-Ser-Leu-7-amino-4-carbamoylcoumarin | — | — | 4.5 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-His-His-Ser-Leu-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Trypanosoma brucei | acetyl-norleucyl-Arg-norleucyl-Arg-7-amino-4-carbamoylcoumarin | 8.15 | 0.67 | 12.2 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-norleucyl-Arg-norleucyl-Arg-7-amino-4-carbamoylcoumarin |
| 20 S proteasome | Trypanosoma brucei | acetyl-Tyr-Trp-Thr-Gln-7-amino-4-carbamoylcoumarin | 4.67 | 0.038 | 120.4 | pH 7.5 | PMID 12600991 | Open record: 20 S proteasome, acetyl-Tyr-Trp-Thr-Gln-7-amino-4-carbamoylcoumarin |