CatLogenzyme kinetics catalog

EC 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase

HydrolasesOpen in Browse

CatLog read 10 records for EC 3.5.1.108 from 1 paper, for 1 organism. Names in these papers: UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 15 records for EC 3.5.1.108 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.108 in Browse.

Papers

PaperOrganismsRecords
Catalytic mechanism and molecular recognition of E. coli UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase probed by mutagenesisEscherichia coli10

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant D197AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine1.50.00111.42 × 10³pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant D197EEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine1.328 × 10⁻⁴1.67 × 10³pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant F192AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.00525 × 10⁻⁴12pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant H19AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.0170.001313pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant H19QEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.130.002457pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant H19YEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.250.01122pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant K143AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine——10pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant K239AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.018 × 10⁻⁴13pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant N162AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine——6.7pH 7.5, 30 °CPMID 17176046Open
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)variant T191AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine0.0530.001633pH 7.5, 30 °CPMID 17176046Open